Outputs (45)

Motivation to Reduce Drinking and Engagement in Alcohol Misuse Treatment in Alcohol-Related Liver Disease: A National Health Survey (2021)
Journal Article
Kann, A. E., Jepsen, P., Madsen, L., Crooks, C., Fleming, K., Christensen, A. I., Lau, C. J., West, J., & Askgaard, G. (2022). Motivation to Reduce Drinking and Engagement in Alcohol Misuse Treatment in Alcohol-Related Liver Disease: A National Health Survey. American Journal of Gastroenterology, 117(6), 918-922. https://doi.org/10.14309/ajg.0000000000001616

INTRODUCTION: The study aim was to identify predictors of motivation to reduce alcohol consumption and whether motivation predicts engagement in alcohol misuse treatment in alcohol-related liver disease (ALD). METHODS: Data from health surveys and he... Read More about Motivation to Reduce Drinking and Engagement in Alcohol Misuse Treatment in Alcohol-Related Liver Disease: A National Health Survey.

Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England (2021)
Journal Article
West, J., Card, T. R., Bishton, M. J., Lanyon, P., Ban, L., Bythell, M., Elliss-Brookes, L., Manson, J. J., Nanduri, V., Rankin, J., Tattersall, R. S., & Crooks, C. J. (2022). Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England. Journal of Internal Medicine, 291(4), 493-504. https://doi.org/10.1111/joim.13432

Background: Haemophagocytic lymphohistiocytosis (HLH) is a rare hyper-inflammatory condition with poor outcomes. Objectives: Few population-based estimates of the incidence and survival in adults exist. We aimed to provide these data for England. Met... Read More about Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England.

Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity (2021)
Journal Article
Innes, H., Crooks, C. J., Aspinall, E., Card, T. R., Hamill, V., Dillon, J., Guha, N. I., Hayes, P. C., Hutchinson, S., West, J., & Morling, J. R. (2022). Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity. Hepatology, 75(2), 369-378. https://doi.org/10.1002/hep.32123

Background and Aims: It is thought that alcohol intake and body mass index (BMI) interact supra-additively to modulate the risk of cirrhosis, but evidence for this phenomenon is limited. We investigated the interrelationship between alcohol and BMI o... Read More about Characterizing the risk interplay between alcohol intake and body mass index on cirrhosis morbidity.

A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data (2021)
Journal Article
Bishton, M. J., Stilwell, P., Card, T. R., Lanyon, P., Ban, L., Elliss-Brookes, L., Manson, J., Nanduri, V., Earp, K., Flower, L., Amarnani, R., Rankin, J., Sen, E. S., Tattersall, R. S., Crooks, C. J., Aston, J., Siskova, V., West, J., & Bythell, M. (2021). A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data. British Journal of Haematology, 194(6), 1039-1044. https://doi.org/10.1111/bjh.17768

We assessed the validity of coded healthcare data to identify cases of haemophagocytic lymphohistiocytosis (HLH). Hospital Episode Statistics (HES) identified 127 cases within five hospital Trusts 2013–2018 using ICD-10 codes D76.1, D76.2 and D76.3.... Read More about A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data.

Socioeconomic inequalities in the incidence of alcohol-related liver disease: A nationwide Danish study (2021)
Journal Article
Askgaard, G., Fleming, K. M., Crooks, C., Kraglund, F., Jensen, C. B., West, J., & Jepsen, P. (2021). Socioeconomic inequalities in the incidence of alcohol-related liver disease: A nationwide Danish study. Lancet Regional Health – Europe, 8, 1-9. https://doi.org/10.1016/j.lanepe.2021.100172

Background: There is socio-economic inequality in total alcohol-related harm, but knowledge of inequality in the incidence of specific alcohol-related diseases would be beneficial for prevention. Registry-based studies with nationwide coverage may re... Read More about Socioeconomic inequalities in the incidence of alcohol-related liver disease: A nationwide Danish study.

External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk (2021)
Journal Article
Ban, L., Abdul Sultan, A., West, J., Tata, L. J., Riley, R. D., Nelson-Piercy, C., & Grainge, M. J. (2021). External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk. Thrombosis Research, 208, 202-210. https://doi.org/10.1016/j.thromres.2021.05.020

Introduction: Venous thromboembolism (VTE) is the leading cause of direct maternal mortality in high-income countries. We previously developed a risk prediction score for postpartum venous thromboembolism (VTE) in women without a previous VTE. In thi... Read More about External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk.

Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study (2021)
Journal Article
Adiamah, A., Ban, L., Otete, H., Crooks, C. J., West, J., & Humes, D. J. (2021). Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study. BJS Open, 5(2), Article zraa073. https://doi.org/10.1093/bjsopen/zraa073

BACKGROUND: The management of perforated diverticular disease has changed in the past 10 years with a move towards less surgical intervention. This population-based cohort study aimed to define the risk of death and readmission following non-operativ... Read More about Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study.

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study (2020)
Journal Article
Manson, J. J., Crooks, C., Naja, M., Ledlie, A., Goulden, B., Liddle, T., Khan, E., Mehta, P., Martin- Gutierrez, L., Waddington, K. E., Robinson, G. A., Ribeiro Santos, L., McLoughlin, E., Snell, A., Adeney, C., Schim van der Loeff, I., Baker, K. F., Duncan, C. J. A., Hanrath, A. T., Lendrem, B. C., …Tattersall, R. (2020). COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study. The Lancet Rheumatology, 2(10), e594-e602. https://doi.org/10.1016/S2665-9913%2820%2930275-7

Background: A subset of patients with severe COVID-19 develop a hyperinflammatory syndrome, which might contribute to morbidity and mortality. This study explores a specific phenotype of COVID-19-associated hyperinflammation (COV-HI), and its associa... Read More about COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.

Health related quality of life in individuals at high risk of chronic liver disease: Impact of a community diagnostic pathway (2020)
Journal Article
Tildesley, Z., Chalmers, J., Harris, R., West, J., Guha, I. N., & Morling, J. R. (2020). Health related quality of life in individuals at high risk of chronic liver disease: Impact of a community diagnostic pathway. Public Health In Practice, 1, Article 100033. https://doi.org/10.1016/j.puhip.2020.100033

Objectives: There is a lack of understanding of health related quality of life (HRQoL) in chronic liver disease (CLD). With the rising prevalence of alcohol and obesity driven CLD, and the increasing ability to screen for fibrosis, it is important to... Read More about Health related quality of life in individuals at high risk of chronic liver disease: Impact of a community diagnostic pathway.

Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis (2020)
Journal Article
Adiamah, A., Ban, L., Hammond, J., Jepsen, P., West, J., & Humes, D. .. (2020). Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis. Alcohol and Alcoholism, 55(5), 497–511. https://doi.org/10.1093/alcalc/agaa043

Aims: This meta-analysis aimed to define the perioperative risk of mortality in patients with alcoholic liver disease (ALD) undergoing extrahepatic gastrointestinal surgery.

Methods: Systematic searches of Embase, Medline and CENTRAL were undertak... Read More about Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis.