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Outputs (547)

Comorbidities in patients with gout prior to and following diagnosis: case-control study (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2016). Comorbidities in patients with gout prior to and following diagnosis: case-control study. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206410

OBJECTIVES: To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis.

METHODS: There were 39 111 patients with incident gout and 39 111 matched controls identified fro... Read More about Comorbidities in patients with gout prior to and following diagnosis: case-control study.

Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women (2015)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Spector, T. D., Hart, D., Cooper, C., Newton, J., & Arden, N. K. (2016). Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women. Annals of the Rheumatic Diseases, 75(10), 1749-1756. https://doi.org/10.1136/annrheumdis-2015-208056

To assess whether joint pain or radiographic osteoarthritis (ROA) of the knee and hand is associated with all-cause and disease-specific mortality in middle-aged women.

Methods: Four subgroups from the prospective community-based Chingford Cohort... Read More about Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women.

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population (2015)
Journal Article
Sekula, P., Goek, O.-N., Quaye, L., Barrios, C., Levey, A. S., Römisch-Margl, W., Menni, C., Yet, I., Gieger, C., Inker, L. A., Adamski, J., Gronwald, W., Illig, T., Dettmer, K., Krumsiek, J., Oefner, P. J., Valdes, A., Meisinger, C., Coresh, J., Spector, T. D., …Köttgen, A. (2015). A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. Journal of the American Society of Nephrology, 27(4), 1175-1188. https://doi.org/10.1681/ASN.2014111099

Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis (2015)
Journal Article
Prieto-Potin, I., Largo, R., Roman-Blas, J. A., Herrero-Beaumont, G., & Walsh, D. A. (2015). Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis. BMC Musculoskeletal Disorders, 16, Article 226. https://doi.org/10.1186/s12891-015-0664-5

Background: Multinucleated giant cells have been noticed in diverse arthritic conditions since their first description in rheumatoid synovium. However, their role in the pathogenesis of osteoarthritis (OA) or rheumatoid arthritis (RA) still remains b... Read More about Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis.

Validity of the disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and the Quickdash when used in Dupuytren’s disease (2015)
Journal Article
Rodrigues, J., Zhang, W., Scammell, B. E., Russell, P., Chakrabarti, I., Fullilove, S., Davidson, D., & Davis, T. (2016). Validity of the disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and the Quickdash when used in Dupuytren’s disease. Journal of Hand Surgery (European Volume), 41(6), https://doi.org/10.1177/1753193415601350

This study investigated aspects of the validity and reliability of the 30-item Disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and its relationship with the shorter 11-item QuickDASH in patients with Dupuytren’s dis... Read More about Validity of the disabilities of the Arm, Shoulder and Hand patient-reported outcome measure (DASH) and the Quickdash when used in Dupuytren’s disease.

Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis (2015)
Journal Article
Williamson, W., Kluzek, S., Roberts, N., Richards, J., Arden, N., Leeson, P., Newton, J., & Foster, C. (2015). Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis. BMJ Open, 5(8), Article e007642. https://doi.org/10.1136/bmjopen-2015-007642

Objective: To assess effectiveness of osteoarthritis interventions to promote long-term physical activity behaviour change.

Design: A systematic review and meta-analysis. Protocol registration PROSPERO CRD4201300444 5 (http://www.crd.york.ac.uk/pr... Read More about Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Valdes, A. M., See, L.-C., Luo, S.-F., Yu, K.-H., Zhang, W., & Doherty, M. (2015). Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families. JAMA Internal Medicine, 175(9), 1518-1526. https://doi.org/10.1001/jamainternmed.2015.3528

IMPORTANCE: Relatives of patients with systemic lupus erythematosus (SLE) appear to be at higher risk of SLE and other autoimmune diseases, but estimates of individual familial risks are largely unavailable or unreliable. Furthermore, relative contri... Read More about Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families.

Causes of death in people with liver cirrhosis in England compared to the general population: a population-based cohort study (2015)
Journal Article
Ratib, S., Fleming, K. M., Crooks, C. J., Walker, A. J., & West, J. (2015). Causes of death in people with liver cirrhosis in England compared to the general population: a population-based cohort study. American Journal of Gastroenterology, 110, https://doi.org/10.1038/ajg.2015.191

Introduction Liver cirrhosis is increasing worldwide and associated with high mortality. Precise estimates of cause-specific mortality compared to the general population, by underlying aetiology, are lacking. Such information may demonstrate areas w... Read More about Causes of death in people with liver cirrhosis in England compared to the general population: a population-based cohort study.