Outputs (559)

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article
Alothman, D., Marshall, C. R., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. (2022). Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England. Journal of Neurology, 269, 4436–4439. https://doi.org/10.1007/s00415-022-11085-z

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.

Introducing genetic testing with case finding for familial hypercholesterolaemia in primary care: qualitative study of patient and health professional experience (2022)
Journal Article
Silva, L., Condon, L., Qureshi, N., Dutton, B., Weng, S., & Kai, J. (2022). Introducing genetic testing with case finding for familial hypercholesterolaemia in primary care: qualitative study of patient and health professional experience. British Journal of General Practice, 72(720), e519-e527. https://doi.org/10.3399/BJGP.2021.0558

Background: Familial hypercholesterolaemia (FH) is a common inherited condition causing elevated cholesterol, premature heart disease and early death. Although FH can be effectively treated, over 80% of people with FH remain undetected.

Aim: To e... Read More about Introducing genetic testing with case finding for familial hypercholesterolaemia in primary care: qualitative study of patient and health professional experience.

Diabetic retinopathy for the non-ophthalmologist (2022)
Journal Article
Fung, T. H., Patel, B., Wilmot, E. G., & Amoaku, W. M. (2022). Diabetic retinopathy for the non-ophthalmologist. Clinical Medicine, 22(2), 112-116. https://doi.org/10.7861/clinmed.2021-0792

Diabetic retinopathy is a microangiopathy resulting from the chronic effects of diabetes mellitus. Healthcare professionals often work in isolation to deliver highly specialised care efficiently and effectively for people living with diabetes. It is... Read More about Diabetic retinopathy for the non-ophthalmologist.

Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial (2022)
Journal Article
Hancox, J., Ayling, K., Bedford, L., Vedhara, K., Robertson, J. F. R., Young, B., das Nair, R., Sullivan, F. M., Schembri, S., Mair, F. S., Littleford, R., & Kendrick., D. (2023). Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial. Journal of Public Health, 45(2), e275–e284. https://doi.org/10.1093/pubmed/fdac032

Background: The Early CDT®-Lung antibody blood test plus serial CT-scans for test-positives reduces late-stage lung cancer presentation. This study assessed psychological outcomes of this approach.

Methods: Randomised controlled trial (n=12,208) c... Read More about Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial.

When is Subnational, Supralocal Tobacco Control "just right"? A Qualitative Study in England (2022)
Journal Article
Davies, N., Cheeseman, H., Arnott, D., Pierce, E., Langley, T. E., Murray, R., Bogdanovica, I., & Bains, M. (2022). When is Subnational, Supralocal Tobacco Control "just right"? A Qualitative Study in England. Nicotine and Tobacco Research, 24(8), 1241-1246. https://doi.org/10.1093/ntr/ntac069

Introduction: Subnational, supralocal (or "regional") approaches to tobacco control are often central federal nation tobacco control and can be superfluous for very small nations. However, their relevance to countries with weak intermediate tiers of... Read More about When is Subnational, Supralocal Tobacco Control "just right"? A Qualitative Study in England.

The development and acceptability testing of an app-based smart survey system to record smoking behaviour, use of nicotine replacement therapy (NRT) and e-cigarettes (2022)
Journal Article
Huang, Y., Emery, J., Naughton, F., Cooper, S., McDaid, L., Dickinson, A., Clark, M., Kinahan-Goodwin, D., Thomson, R., Phillips, L., Lewis, S., Orton, S., & Coleman, T. (2022). The development and acceptability testing of an app-based smart survey system to record smoking behaviour, use of nicotine replacement therapy (NRT) and e-cigarettes. BMC Research Notes, 15(1), Article 100. https://doi.org/10.1186/s13104-022-05983-8

Objective: Nicotine replacement therapy (NRT) helps people stop smoking. Monitoring treatment adherence is important as poor adherence to NRT limits its effectiveness. As e-cigarettes contain nicotine, their use (‘vaping’) is likely to affect both NR... Read More about The development and acceptability testing of an app-based smart survey system to record smoking behaviour, use of nicotine replacement therapy (NRT) and e-cigarettes.

The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic (2022)
Journal Article
Jia, R., Ayling, K., Chalder, T., Massey, A., Gasteiger, N., Broadbent, E., Coupland, C., & Vedhara, K. (2022). The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic. BJPsych Open, 8(2), Article e64. https://doi.org/10.1192/bjo.2022.34

Background The COVID-19 pandemic has had profound consequences for population mental health. However, it is less clear for whom these effects are sustained. Aims To investigate the prevalence, incidence, prognosis and risk factors for symptoms of dep... Read More about The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic.

Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., & Coupland, C. (2022). Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records. Evidence-Based Mental Health, 25(4), 169-176. https://doi.org/10.1136/ebmental-2021-300355

BACKGROUND: Studies report an increased risk of self-harm or suicide in people prescribed mirtazapine compared with other antidepressants. OBJECTIVES: To compare the risk of serious self-harm in people prescribed mirtazapine versus other antidepressa... Read More about Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records.

Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group (2022)
Journal Article
Bridger, K., Kellezi, B., Kendrick, D., Kettlewell, J., Holmes, J., Timmons, S., Andrews, I., Fallon, S., & Radford, K. (2022). Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group. British Journal of Occupational Therapy, 85(9), 704-711. https://doi.org/10.1177/03080226211072766

Objective: Injuries can have a long-lasting effect on ability to return to work, but there is little research on which outcomes are most important to patients. This study aims to identify and prioritise return-to-work outcomes important to patients f... Read More about Patients views on which return-to-work outcomes should be prioritised: A nominal group technique focus group.

Development of a Smoke-Free Home Intervention for Families of Babies Admitted to Neonatal Intensive Care (2022)
Journal Article
Notley, C., Brown, T. J., Bauld, L., Boyle, E. M., Clarke, P., Hardeman, W., Holland, R., Hubbard, M., Naughton, F., Nichols, A., Orton, S., Ussher, M., & Ward, E. (2022). Development of a Smoke-Free Home Intervention for Families of Babies Admitted to Neonatal Intensive Care. International Journal of Environmental Research and Public Health, 19(6), Article 3670. https://doi.org/10.3390/ijerph19063670

Neonatal intensive care units (NICUs) have a disproportionately higher number of parents who smoke tobacco compared to the general population. A baby’s NICU admission offers a unique time to prompt behaviour change, and to emphasise the dangerous hea... Read More about Development of a Smoke-Free Home Intervention for Families of Babies Admitted to Neonatal Intensive Care.