Outputs (75)

Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400,000 children and young people (CYP) aged 0-19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT) (2022)
Journal Article
Stevenson, D. J., Avery, A. J., Coupland, C., Hobbs, F. D. R., Kendrick, D., Moore, M. V., Morris, C., Rubin, G. P., Smith, M. D., Hawkey, C. J., & Dumbleton, J. S. (2022). Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT). Trials, 23(1), Article 140. https://doi.org/10.1186/s13063-022-06054-w

Background: The Helicobacter Eradication Aspirin Trial (HEAT) is a multicentre, double blind, randomised controlled trial investigating whether Helicobacter (H.) pylori eradication reduces hospitalisation for peptic ulcer bleeding. Recruited particip... Read More about Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT).

Development of models of care coordination for rare conditions: A qualitative study (2022)
Journal Article
Walton, H., Simpson, A., Ramsay, A. I., Hunter, A., Jones, J., Ng, P. L., Leeson-Beevers, K., Bloom, L., Kai, J., Kokocinska, M., Sutcliffe, A. G., Morris, S., & Fulop, N. J. (2022). Development of models of care coordination for rare conditions: A qualitative study. Orphanet Journal of Rare Diseases, 17, Article 49. https://doi.org/10.1101/2021.11.16.21266395

Introduction: Improving care coordination for people with rare conditions may help to reduce burden on patients and carers and improve the care that patients receive. We recently developed a taxonomy of different ways of coordinating care for rare co... Read More about Development of models of care coordination for rare conditions: A qualitative study.

‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme (2022)
Journal Article
Gumber, L., Timmons, S., Coupland, C., Gladman, J., Lliffe, S., Kendrick, D., Lafond, N., Logan, P., Masud, T., Skelton, D., Timblin, C., & Orton, E. (2022). ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme. Age and Ageing, 51(2), Article afac023. https://doi.org/10.1093/ageing/afac023

Background: Older adults are at increased risk of falls due to ageing, decreased muscle strength and impaired balance. Clinical trials have demonstrated the efficacy and effectiveness of the Falls Management Exercise (FaME) programme in improving fun... Read More about ‘It is designed for everybody to find their own level and to improve themselves’; views of older people and instructors of the Falls Management Exercise (FaME) programme.

Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study (2022)
Journal Article
Beckett, K., Deave, T., McBride, T., May, A. L., Gabbay, J., Kapoulas, U., Long, A., Warburton, G., Wogan, C., Cox, L., Thompson, J., Spencer, F., & Kendrick, D. (2022). Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study. Evidence and Policy, 18(2), 236-264. https://doi.org/10.1332/174426421X16420902769508

Background: Evidence regarding the impact of psychological problems on recovery from injury has limited influence on practice. Mindlines show effective practice requires diverse knowledge which is generally socially transmitted. Aims and objectives:... Read More about Using Forum Theatre to mobilise knowledge and improve NHS care: the Enhancing Post-injury Psychological Intervention and Care (EPPIC) study.

Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’ (2022)
Journal Article
Perkins, P., Parkinson, A., Hebdon, R., & Akyea, R. K. (2022). Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’. Journal of Pain and Symptom Management, 63(6), e691-697. https://doi.org/10.1016/j.jpainsymman.2022.01.018

Context: Some patients take their strong opioid painkillers as unmeasured sips. Objectives: To investigate how and why patients take their medication in this way. Methods: Patient receiving specialist palliative care who take their strong opioid pain... Read More about Behaviours of Patients Who Take Their Strong Opioids as Unmeasured ‘Sips’.

The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., & Coupland, C. (2022). The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records. BMC Medicine, 20(1), Article 43. https://doi.org/10.1186/s12916-022-02247-x

Background
Studies have reported an increased risk of mortality among people prescribed mirtazapine compared to other antidepressants. The study aimed to compare all-cause and cause-specific mortality between adults prescribed mirtazapine or other s... Read More about The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records.

Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets (2022)
Journal Article
Burchardt, J. M., Mei, X. W., Ranger, T., McDermott, C. J., Radunovic, A., Coupland, C., & Hippisley-Cox, J. (2022). Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23(5-6), 363-371. https://doi.org/10.1080/21678421.2021.2016837

Objective: This study uses three linked datasets to provide an estimate of incidence of motor neuron disease (MND) in England from 1998 to 2019. Comparison is made to previous British studies. It examines age at diagnosis and ethnicity of those affec... Read More about Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets.

Smoking Cessation Support for Pregnant Women Provided by English Stop Smoking Services and National Health Service Trusts: A Survey (2022)
Journal Article
Thomson, R., Cooper, S., Waldron, J., Mamuzo, E., McDaid, L., Emery, J., Phillips, L., Naughton, F., & Coleman, T. (2022). Smoking Cessation Support for Pregnant Women Provided by English Stop Smoking Services and National Health Service Trusts: A Survey. International Journal of Environmental Research and Public Health, 19(3), Article 1634. https://doi.org/10.3390/ijerph19031634

Reducing smoking rates in pregnancy continues to be a public health priority. Given a recent UK government policy change resulting in The National Health Service (NHS) making a significant new contribution to cessation support in pregnancy in England... Read More about Smoking Cessation Support for Pregnant Women Provided by English Stop Smoking Services and National Health Service Trusts: A Survey.

Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021 (2022)
Journal Article
Abhishek, A., Tata, L. J., Mamas, M., & Avery, A. J. (2022). Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021. Annals of the Rheumatic Diseases, 81(6), 898-899. https://doi.org/10.1136/annrheumdis-2021-221989