Comparision of the DNA binding properties of the E2 proteins from a high-risk and a low-risk HPV
(2001)
Presentation / Conference Contribution
Dell, G., Parish, J., & Gaston, K. (2000, December). Comparision of the DNA binding properties of the E2 proteins from a high-risk and a low-risk HPV
Outputs (6)
Combination of progesterone and mifepristone for cancer therapy (2001)
Other
Gaston, K. (2001). Combination of progesterone and mifepristone for cancer therapy. n/aUse of a steroid hormone or steroid hormone analogue and at least a portioUse of a steroid hormone or steroid hormone analogue and at least a portion of HPV E2 protein in the preparation of a pharmaceutical composition for the treatment of cervical c... Read More about Combination of progesterone and mifepristone for cancer therapy.
Human T-cell responses to HPV 16 E2 generated with monocyte-derived dendritic cells (2001)
Journal Article
Davidson, E. J., Brown, M. D., Burt, D. J., Parish, J. L., Gaston, K., Kitchener, H. C., Stacey, S. N., & Stern, P. L. (2001). Human T-cell responses to HPV 16 E2 generated with monocyte-derived dendritic cells. International Journal of Cancer, 94(6), 807-812. https://doi.org/10.1002/ijc.1558Persistent infection with human papillomavirus (HPV) type 16 has been implicated in the etiology of cervical cancer. The E2 protein is required early in viral infection and therefore may serve as a useful immune target for a vaccine aimed at preventi... Read More about Human T-cell responses to HPV 16 E2 generated with monocyte-derived dendritic cells.
Contributions in the domain of cancer research: Review¶Human papillomaviruses and their role in cervical cancer (2001)
Journal Article
Dell, G., & Gaston, K. (2001). Contributions in the domain of cancer research: Review¶Human papillomaviruses and their role in cervical cancer. Cellular and Molecular Life Sciences, 58(12), 1923-1942. https://doi.org/10.1007/pl00000827Human papillomaviruses (HPVs) have been linked to a variety of human diseases, most notably cancer of the cervix, a disease responsible for at least 200,000 deaths per year worldwide. Over 100 different types of HPV have been identified and these can... Read More about Contributions in the domain of cancer research: Review¶Human papillomaviruses and their role in cervical cancer.
Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins (2001)
Journal Article
Webster, K., Taylor, A., & Gaston, K. (2001). Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins. Journal of General Virology, 82(1), 201-213. https://doi.org/10.1099/0022-1317-82-1-201Human papillomavirus (HPV) type 16 infects the genital tract and is generally acknowledged to be a causative agent of cervical cancer. HPV infection alone is not sufficient to induce cervical cancer and other factors such as steroid hormones are thou... Read More about Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins.
Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer (2001)
Journal Article
Rampaul, R., Miremadi, A., Pinder, S., Lee, A., & Ellis, I. (2001). Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer. Breast Cancer Research, 3(2),In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The consequences of missing sentinel node micrometastasis ca... Read More about Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer.