Outputs (2)

Generation of Hepatocytes from Pluripotent Stem Cells for Drug Screening and Developmental Modeling. (2014)
Journal Article
GieseckIII, R. L., Vallier, L., & Hannan, N. (2015). Generation of Hepatocytes from Pluripotent Stem Cells for Drug Screening and Developmental Modeling. Methods in Molecular Biology, 1250, 123-142. https://doi.org/10.1007/978-1-4939-2074-7_9

Hepatocytes produced from the differentiation of human pluripotent stem cells can be used to study human development and liver disease, to investigate the toxicological response of novel drug candidates, and as an alternative source of primary cells... Read More about Generation of Hepatocytes from Pluripotent Stem Cells for Drug Screening and Developmental Modeling..

Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture (2014)
Journal Article
Gieseck, R. L., Hannan, N. R., Gieseck III, R., Bort, R., Hanley, N., Drake, R., Cameron, G., Wynn, T., & Vallier, L. (2014). Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PLoS ONE, 9(1), Article e86372. https://doi.org/10.1371/journal.pone.0086372

Induced pluripotent stem cell derived hepatocytes (IPSC-Heps) have the potential to reduce the demand for a dwindling number of primary cells used in applications ranging from therapeutic cell infusions to in vitro toxicology studies. However, curren... Read More about Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture.