Outputs (2)

c-Met inhibition in aHOXA9/Meis1model of CN-AML (2013)
Journal Article
Mulgrew, N. M., Kettyle, L. M., Ramsey, J. M., Cull, S., Smyth, L. J., Mervyn, D. M., Bijl, J. J., & Thompson, A. (2013). c-Met inhibition in aHOXA9/Meis1model of CN-AML. Developmental Dynamics, 243(1), https://doi.org/10.1002/dvdy.24070

Background: Hematopoiesis is a paradigm for developmental processes, hierarchically organized, with stem cells at its origin. Hematopoietic stem cells (HSCs) replenish progenitor and precursor cells of multiple lineages, which normally differentiate... Read More about c-Met inhibition in aHOXA9/Meis1model of CN-AML.

Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression (2013)
Journal Article
Hassawi, M., Shestakova, E. A., Fournier, M., Lebert-Ghali, C.-É., Vaisson, G., Frison, H., Sinnett, D., Vidal, R., Thompson, A., & Bijl, J. J. (2014). Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression. Developmental Dynamics, 243(1), 145-158. https://doi.org/10.1002/dvdy.24056

Background: The fusion protein E2A-PBX1 induces pediatric B cell leukemia in human. Previously, we reported oncogenic interactions between homeobox (Hox) genes and E2A-PBX1 in murine T cell leukemia. A proviral insertional mutagenesis screen with our... Read More about Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression.