Outputs (127)

Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus (2021)
Journal Article
Nixon, A. L., Chattopadhyay, K., & Leonardi-Bee, J. (2021). Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus. International Journal of Environmental Research and Public Health, 18(24), Article 12868. https://doi.org/10.3390/ijerph182412868

Purpose: Type 2 diabetes mellitus (T2DM) is poorly managed in the Caribbean; therefore, con-ducting an assessment of the content and quality of clinical guidelines will allow guideline de-velopers to detect and address the lacking information. Hence,... Read More about Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus.

Large-scale implementation of stroke early supported discharge: the WISE realist mixed-methods study (2021)
Journal Article
Fisher, R. J., Chouliara, N., Byrne, A., Cameron, T., Lewis, S., Langhorne, P., Robinson, T., Waring, J., Geue, C., Paley, L., Rudd, A., & Walker, M. F. (in press). Large-scale implementation of stroke early supported discharge: the WISE realist mixed-methods study. Health Services and Delivery Research, 9(22), 1-150. https://doi.org/10.3310/hsdr09220

Background
In England, the provision of early supported discharge is recommended as part of an evidence-based stroke care pathway.

Objectives
To investigate the effectiveness of early supported discharge services when implemented at scale in pra... Read More about Large-scale implementation of stroke early supported discharge: the WISE realist mixed-methods study.

Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol (2021)
Journal Article
Knight, S. R., Gupta, R. K., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., Dunning, J., Fairfield, C. J., Gamble, C., Green, C. A., Halpin, S., Hardwick, H. E., Holden, K. A., Horby, P. W., Jackson, C., Mclean, K. A., Merson, L., Nguyen-Van-Tam, J. S., Norman, L., …Harrison, E. M. (2022). Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. Thorax, 77(6), 606-615. https://doi.org/10.1136/thoraxjnl-2021-217629

Purpose: To prospectively validate two risk scores to predict mortality (4C Mortality) and in hospital deterioration (4C Deterioration) among adults hospitalised with coronavirus disease 2019 (covid-19).

Methods: Prospective observational cohort... Read More about Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol.

Ethnicity and suicide risk: A population-based study from England (2021)
Journal Article
Alothman, D., Fogarty, A., Tyrrell, E., Lewis, S., & Card, T. (2022). Ethnicity and suicide risk: A population-based study from England. Journal of Affective Disorders, 298(Part A), 555-557. https://doi.org/10.1016/j.jad.2021.11.044

Using multiple linked electronic health databases, we conducted a large case-control study in England from 2001 through 2019 to examine the association between ethnicity and suicide risk. Asian, Black and Other ethnic groups had a significantly lower... Read More about Ethnicity and suicide risk: A population-based study from England.

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Preprint / Working Paper
Usman, A., Lewis, S., Clarkson, P., & Gordon, A. Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol

Introduction
There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial (2021)
Journal Article
Lazarus, R., Baos, S., Cappel-Porter, H., Carson-Stevens, A., Clout, M., Culliford, L., Emmett, S. R., Garstang, J., Gbadamoshi, L., Hallis, B., Harris, R. A., Hutton, D., Jacobsen, N., Joyce, K., Kaminski, R., Libri, V., Middleditch, A., McCullagh, L., Moran, E., Phillipson, A., …and the ComfluCOV Trial Group. (2021). Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial. Lancet, 398(10318), 2277-2287. https://doi.org/10.1016/s0140-6736%2821%2902329-1

Background: Concomitant administration of COVID-19 and influenza vaccines could reduce burden on health-care systems. We aimed to assess the safety of concomitant administration of ChAdOx1 or BNT162b2 plus an age-appropri... Read More about Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial.

Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? protocol for a feasibility randomised controlled trial (2021)
Journal Article
Subhani, M., Jones, K. A., Sprange, K., Rennick-Egglestone, S., Knight, H., Morling, J. R., Enki, D. G., Wragg, A., & Ryder, S. D. (2021). Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? protocol for a feasibility randomised controlled trial. BMJ Open, 11(11), Article e054954. https://doi.org/10.1136/bmjopen-2021-054954

Introduction Heavy drinkers in contact with alcohol services do not routinely have access to testing to establish the severity of potential liver disease. Transient elastography by FibroScan can provide this information. A recent systematic review su... Read More about Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? protocol for a feasibility randomised controlled trial.

Anti-reflux medication use in preterm infants (2021)
Journal Article
Binti Abdul Hamid, H., Szatkowski, L., Budge, H., & Ojha, S. (2022). Anti-reflux medication use in preterm infants. Pediatric Research, 92, 520-525. https://doi.org/10.1038/s41390-021-01821-y

Background: Current recommendations do not support the use of anti-reflux medications to treat gastro-oesophageal reflux disease (GORD) among preterm infants. Objective: To describe the prevalence of GORD and the use of anti-reflux medications amongs... Read More about Anti-reflux medication use in preterm infants.

Selection of eligible participants for screening for lung cancer using primary care data (2021)
Journal Article
O’Dowd, E. L., Ten Haaf, K., Kaur, J., Duffy, S. W., Hamilton, W., Hubbard, R. B., Field, J. K., Callister, M. E., Janes, S. M., de Koning, H., Rawlinson, J., & Baldwin, D. R. (2022). Selection of eligible participants for screening for lung cancer using primary care data. Thorax, 77(9), 882-890. https://doi.org/10.1136/thoraxjnl-2021-217142

Lung cancer screening is effective if offered to people at increased risk of the disease. Currently, direct contact with potential participants is required for evaluating risk. A way to reduce the number of ineligible people contacted might be to app... Read More about Selection of eligible participants for screening for lung cancer using primary care data.

Barriers and Facilitators to Staying Smoke-Free after Having a Baby, a Qualitative Study: Women’s Views on Support Needed to Prevent Returning to Smoking Postpartum (2021)
Journal Article
Phillips, L., Campbell, K. A., Coleman, T., Ussher, M., Cooper, S., Lewis, S., & Orton, S. (2021). Barriers and Facilitators to Staying Smoke-Free after Having a Baby, a Qualitative Study: Women’s Views on Support Needed to Prevent Returning to Smoking Postpartum. International Journal of Environmental Research and Public Health, 18(21), Article 11358. https://doi.org/10.3390/ijerph182111358

Background: Postpartum return to smoking (PPRS) is a common and important public health problem. Interventions to prevent PPRS have not been shown to be effective. We aimed to qualitatively explore the barriers and facilitators to staying smoke-free... Read More about Barriers and Facilitators to Staying Smoke-Free after Having a Baby, a Qualitative Study: Women’s Views on Support Needed to Prevent Returning to Smoking Postpartum.