Outputs (128)

COVID-19 Vaccine Response in People with Multiple Sclerosis (2021)
Journal Article
Tallantyre, E. C., Vickaryous, N., Anderson, V., Asardag, A. N., Baker, D., Bestwick, J., Bramhall, K., Chance, R., Evangelou, N., George, K., Giovannoni, G., Godkin, A., Grant, L., Harding, K. E., Hibbert, A., Ingram, G., Jones, M., Kang, A. S., Loveless, S., Moat, S. J., …Dobson, R. (2022). COVID-19 Vaccine Response in People with Multiple Sclerosis. Annals of Neurology, 91(1), 89-100. https://doi.org/10.1002/ana.26251

Objective: The purpose of this study was to investigate the effect of disease modifying therapies on immune response to severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccines in people with multiple sclerosis (MS). Methods: Four hundre... Read More about COVID-19 Vaccine Response in People with Multiple Sclerosis.

Memory rehabilitation for people with multiple sclerosis (2021)
Journal Article
Taylor, L. A., Mhizha-Murira, J. R., Smith, L., Potter, K.-J., Wong, D., Evangelou, N., Lincoln, N. B., & das Nair, R. (2021). Memory rehabilitation for people with multiple sclerosis. Cochrane Library, 2021(10), Article CD008754. https://doi.org/10.1002/14651858.cd008754.pub4

Background
Problems with cognition, particularly memory, are common in people with multiple sclerosis (MS) and can affect their ability to complete daily activities and can negatively affect quality of life. Over the last few years, there has been c... Read More about Memory rehabilitation for people with multiple sclerosis.

Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials (2021)
Journal Article
Woodhouse, L. J., Montgomery, A. A., Mant, J., Davis, B. R., Algra, A., Mas, J.-L., Staessen, J. A., Thijs, L., Tonkin, A., Kirby, A., Pocock, S. J., Chalmers, J., Hankey, G. J., Spence, J. D., Sandercock, P., Diener, H.-C., Uchiyama, S., Sprigg, N., & Bath, P. M. (2021). Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials. BMC Medical Research Methodology, 21, Article 218. https://doi.org/10.1186/s12874-021-01388-6

Background: Vascular prevention trials typically use dichotomous event outcomes although this may be inefficient statistically and gives no indication of event severity. We assessed whether ordinal outcomes would be more efficient and how to best ana... Read More about Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials.

Sound pressure levels in close proximity to sound-reinforcement speakers (2021)
Presentation / Conference Contribution
Wiggins, I., & Liston, K. (2021, October). Sound pressure levels in close proximity to sound-reinforcement speakers. Presented at ACOUSTICS 2021, Hybrid

Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study (2021)
Journal Article
Maxwell, K., Robinson, J. M., Hoffmann, I., Hou, H. J., Searchfield, G., Baguley, D. M., McMurry, G., Piu, F., & Anderson, J. J. (2021). Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study. Otology and Neurotology, 42(10), e1625-e1633. https://doi.org/10.1097/mao.0000000000003369

Objective:
To evaluate the safety and exploratory efficacy of intratympanic administration of OTO-313 in patients with tinnitus.

Study Design:
Single intratympanic injection of OTO-313 evaluated in a randomized, double-blind, placebo-controlle... Read More about Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study.

User-Operated Audiometry Project (UAud) – Introducing an Automated User-Operated System for Audiometric Testing Into Everyday Clinic Practice (2021)
Journal Article
Sidiras, C., Sanchez-Lopez, R., Pedersen, E. R., Sørensen, C. B., Nielsen, J., & Schmidt, J. H. (2021). User-Operated Audiometry Project (UAud) – Introducing an Automated User-Operated System for Audiometric Testing Into Everyday Clinic Practice. Frontiers in Digital Health, 3, Article 724748. https://doi.org/10.3389/fdgth.2021.724748

Hearing loss is the third leading cause of years lived with disability. It is estimated that 430 million people worldwide are affected, and the number of cases is expected to increase in the future. There is therefore increased pressure on hearing he... Read More about User-Operated Audiometry Project (UAud) – Introducing an Automated User-Operated System for Audiometric Testing Into Everyday Clinic Practice.

COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register (2021)
Journal Article
Middleton, R. M., Craig, E. M., Rodgers, W. J., Tuite-Dalton, K., Garjani, A., Evangelou, N., das Nair, R., Hunter, R., Tallantyre, E. C., Cauchi, M., Cairn, C., Paling, D., Fuller, S., McDonnell, G., Petherham, K., Liu, B., Nock, U., Ingram, G., Brownlee, W., Taylor, J., …UK Multiple Sclerosis Register Research Group. (2021). COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register. Multiple Sclerosis and Related Disorders, 56, Article 103317. https://doi.org/10.1016/j.msard.2021.103317

Background: In March 2020, the United Kingdom Multiple Sclerosis Register (UKMSR) established an electronic case return form, designed collaboratively by MS neurologists, to record data about COVID-19 infections in people with MS (pwMS). Objectives:... Read More about COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register.

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study (2021)
Journal Article
Evans, R. A., McAuley, H., Harrison, E. M., Shikotra, A., Singapuri, A., Sereno, M., Elneima, O., Docherty, A. B., Lone, N. I., Leavy, O. C., Daines, L., Baillie, J. K., Brown, J. S., Chalder, T., De Soyza, A., Diar Bakerly, N., Easom, N., Geddes, J. R., Greening, N. J., Hart, N., …Zongo, O. (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet Respiratory Medicine, 9(11), 1275-1287. https://doi.org/10.1016/S2213-2600%2821%2900383-0

Background: The impact of COVID-19 on physical and mental health and employment after hospitalisation with acute disease is not well understood. The aim of this study was to determine the effects of COVID-19-related hospitalisation on health and empl... Read More about Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies (2021)
Journal Article
Ting, D. S. J., Li, J., Verma, C. S., Goh, E. T., Nubile, M., Mastropasqua, L., Said, D. G., Beuerman, R. W., Lakshminarayanan, R., Mohammed, I., & Dua, H. S. (2021). Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies. Frontiers in Pharmacology, 12, Article 731499. https://doi.org/10.3389/fphar.2021.731499

Background/Aim: Host defense peptides (HDPs) have the potential to provide a novel solution to antimicrobial resistance (AMR) in view of their unique and broad-spectrum antimicrobial activities. We had recently developed a novel hybrid HDP based on L... Read More about Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies.

Synchrony as a measure of conversation difficulty: Movement coherence increases with background noise level and complexity in dyads and triads (2021)
Journal Article
Hadley, L. V., & Ward, J. A. (2021). Synchrony as a measure of conversation difficulty: Movement coherence increases with background noise level and complexity in dyads and triads. PLoS ONE, 16(10), Article e0258247. https://doi.org/10.1371/journal.pone.0258247

When people interact, they fall into synchrony. This synchrony has been demonstrated in a range of contexts, from walking or playing music together to holding a conversation, and has been linked to prosocial outcomes such as development of rapport an... Read More about Synchrony as a measure of conversation difficulty: Movement coherence increases with background noise level and complexity in dyads and triads.