Outputs (128)

Ventilation strategies for front of neck airway rescue: an in silico study (2021)
Journal Article
Laviola, M., Niklas, C., Das, A., Bates, D. G., & Hardman, J. G. (2021). Ventilation strategies for front of neck airway rescue: an in silico study. British Journal of Anaesthesia, 126(6), 1226-1236. https://doi.org/10.1016/j.bja.2021.01.030

Background. During induction of general anaesthesia a “can’t intubate, can’t oxygenate” (CICO) situation can arise, leading to severe hypoxaemia. Evidence is scarce to guide ventilation strategies for small-bore front of neck airways that ensure effe... Read More about Ventilation strategies for front of neck airway rescue: an in silico study.

Operculo-Insular and Anterior Cingulate Plasticity Induced by Transcranial Magnetic Stimulation in the Human Motor Cortex: A Dynamic Casual Modelling Study (2021)
Journal Article
Hodkinson, D. J., Bungert, A., Bowtell, R. W., Jackson, S. R., & Jung, J. (2021). Operculo-Insular and Anterior Cingulate Plasticity Induced by Transcranial Magnetic Stimulation in the Human Motor Cortex: A Dynamic Casual Modelling Study. Journal of Neurophysiology, 125(4), 1180-1190. https://doi.org/10.1152/jn.00670.2020

The ability to induce neuroplasticity with non-invasive brain stimulation techniques offers a unique opportunity to examine the human brain systems involved in pain modulation. In experimental and clinical settings, the primary motor cortex (M1) is c... Read More about Operculo-Insular and Anterior Cingulate Plasticity Induced by Transcranial Magnetic Stimulation in the Human Motor Cortex: A Dynamic Casual Modelling Study.

Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial (2021)
Journal Article
Law, Z. K., Desborough, M., Roberts, I., Al‐Shahi Salman, R., England, T. J., Werring, D. J., Robinson, T., Krishnan, K., Dineen, R., Laska, A. C., Peters, N., Egea‐Guerrero, J. J., Karlinski, M., Christensen, H., Roffe, C., Bereczki, D., Ozturk, S., Thanabalan, J., Collins, R., Beridze, M., …Sprigg, N. (2021). Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial. Journal of the American Heart Association, 10(5), Article e019130. https://doi.org/10.1161/jaha.120.019130

Background
Antiplatelet therapy increases the risk of hematoma expansion in intracerebral hemorrhage (ICH) while the effect on functional outcome is uncertain.

Methods and Results
This is an exploratory analysis of the TICH‐2 (Tranexamic Acid in... Read More about Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial.

Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres (2021)
Journal Article
Wallace, M. N., Sumner, C. J., Berger, J. I., McNaughton, P. A., & Palmer, A. R. (2021). Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres. Neuroscience Letters, 747, Article 135705. https://doi.org/10.1016/j.neulet.2021.135705

Tinnitus has similarities to chronic neuropathic pain where there are changes in the firing rate of different types of afferent neurons. We postulated that one possible cause of tinnitus is a change in the distribution of spontaneous firing rates in... Read More about Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres.

Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation (2021)
Journal Article
Stolady, D., Laviola, M., Pillai, A., & Hardman, J. G. (2021). Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation. British Journal of Anaesthesia, 126(4), 889-895. https://doi.org/10.1016/j.bja.2020.12.031

Background

Studies of pulmonary denitrogenation (pre-oxygenation) in obstetric populations have shown high flow nasal oxygen therapy (HFNO) is inferior to facemask techniques. HFNO achieves median end-tidal oxygen fraction (FE′O2) of 0.87 after 3... Read More about Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation.

Tinnitus and Tinnitus Disorder: Theoretical and Operational Definitions (An international multidisciplinary proposal) (2021)
Book Chapter
De Ridder, D., Schlee, W., Vanneste, S., Londero, A., Weisz, N., Kleinjung, T., Singh Shekhawat, G., Belén Elgoyhen, A., Song, J.-J., Andersson, G., Aparecida de Azevedo, A., Baguley, D. M., Biesinger, E., Carolina Binetti, A., Del Bo, L., Cederroth, C. R., Cima, R., Eggermont, J. J., Figueiredo, R., Fuller, T. E., …Langguth, B. (2021). Tinnitus and Tinnitus Disorder: Theoretical and Operational Definitions (An international multidisciplinary proposal). . Elsevier. https://doi.org/10.1016/bs.pbr.2020.12.002

As for hypertension, chronic pain, epilepsy and other disorders with particular symptoms, a commonly accepted and unambiguous definition provides a common ground for researchers and clinicians to study and treat the problem. The WHO's ICD11 definitio... Read More about Tinnitus and Tinnitus Disorder: Theoretical and Operational Definitions (An international multidisciplinary proposal).

Hearing Aids Reduce Daily-Life Fatigue and Increase Social Activity: A Longitudinal Study (2021)
Journal Article
Holman, J. A., Drummond, A., & Naylor, G. (2021). Hearing Aids Reduce Daily-Life Fatigue and Increase Social Activity: A Longitudinal Study. Trends in Hearing, 25, https://doi.org/10.1177/23312165211052786

People with hearing loss experience fatigue, and it is unknown whether this is alleviated by treatment with hearing aids. The objective of this study was to address this issue and to investigate the possible concomitant effect of hearing-aid fitting... Read More about Hearing Aids Reduce Daily-Life Fatigue and Increase Social Activity: A Longitudinal Study.

The prevalence of tinnitus in China: a systematic review of the literature (2021)
Journal Article
Dawei, Z., Xu, Q., Caimino, C., & Baguley, D. M. (2021). The prevalence of tinnitus in China: a systematic review of the literature. Journal of Laryngology and Otology, 135(1), 3-9. https://doi.org/10.1017/S002221512000256X

Purpose: The aim of the present study was to identify reports of the prevalence of tinnitus in China and to present these findings in a review format.
Method: We assessed and collated published prevalence estimates of tinnitus and tinnitus severity,... Read More about The prevalence of tinnitus in China: a systematic review of the literature.

Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA) (2021)
Journal Article
Ní Leidhin, C., McMorrow, J., Carey, D., Newman, L., Williamson, W., Fagan, A. J., Chappell, M. A., Kenny, R. A., Meaney, J. F., & Knight, S. P. (2021). Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA). NeuroImage, 229, Article 117741. https://doi.org/10.1016/j.neuroimage.2021.117741

Objective To establish normative reference values for total grey matter cerebral blood flow (CBFGM) measured using pseudo-continuous arterial spin labelling (pCASL) MRI in a large cohort of community-dwelling adults aged 54 years and older. Backgroun... Read More about Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA).

Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle (2021)
Journal Article
Salvan, P., Wassenaar, T., Wheatley, C., Beale, N., Cottaar, M., Papp, D., Bastiani, M., Fitzgibbon, S., Duff, E., Andersson, J., Winkler, A. M., Douaud, G., Nichols, T. E., Smith, S., Dawes, H., & Johansen-Berg, H. (2021). Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle. Journal of Neuroscience, 41(5), 1092-1104. https://doi.org/10.1523/JNEUROSCI.1260-20.2020

© 2021 Salvan et al. The World Health Organization promotes physical exercise and a healthy lifestyle as means to improve youth development. However, relationships between physical lifestyle and human brain development are not fully understood. Here,... Read More about Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle.