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Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression (2009)
Journal Article
Geeganage, C., & Bath, P. M. (in press). Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression. Hypertension, 54(4), https://doi.org/10.1161/hypertensionaha.109.133538

Both low and high blood pressure (BP) during the acute phase of stroke are associated independently with a poor outcome. Several small clinical trials have involved the alteration of BP and this study assessed the relationship between change in BP an... Read More about Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression.

Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration (2009)
Journal Article
Sare, G. M., Ali, M., Shuaib, A., & Bath, P. M. (2009). Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration. Stroke, 40(6), https://doi.org/10.1161/STROKEAHA.108.539155

Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Methods... Read More about Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration.

Speeding stroke recovery? A systematic review of amphetamine after stroke (2009)
Journal Article
Sprigg, N., & Bath, P. M. (2009). Speeding stroke recovery? A systematic review of amphetamine after stroke. Journal of the Neurological Sciences, 285(1-2), 3-9. https://doi.org/10.1016/j.jns.2009.04.040

Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke. Methods: Elec... Read More about Speeding stroke recovery? A systematic review of amphetamine after stroke.

Stem cells for enhancing recovery after stroke: a review (2009)
Journal Article
England, T. J., Martin, P., & Bath, P. M. (2009). Stem cells for enhancing recovery after stroke: a review. International Journal of Stroke, 4(2),

The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a... Read More about Stem cells for enhancing recovery after stroke: a review.

Good laboratory practice: preventing introduction of bias at the bench (2009)
Journal Article
Macleod, M. R., Fisher, M., O'Collins, V., Sena, E. S., Dirnagl, U., Bath, P. M., …Howells, D. W. (2009). Good laboratory practice: preventing introduction of bias at the bench. Stroke, 40(3), Article e50-e52

Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review—Accumulating evidence sugge... Read More about Good laboratory practice: preventing introduction of bias at the bench.