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Outputs (122)

Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign (2021)
Journal Article
Ovesen, C., Jakobsen, J. C., Gluud, C., Steiner, T., Law, Z., Flaherty, K., …Christensen, H. (2021). Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign. Stroke, 52(8), 2629-2636. https://doi.org/10.1161/strokeaha.120.032426

Background and Purpose: The computed tomography angiography or contrast-enhanced computed tomography based spot sign has been proposed as a biomarker for identifying on-going hematoma expansion in patients with acute intracerebral hemorrhage. We inv... Read More about Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign.

Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies (2021)
Journal Article
Watson, D. M., Akeroyd, M. A., Roach, N. W., & Webb, B. S. (2021). Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies. PLoS ONE, 16(5), 1-21. https://doi.org/10.1371/journal.pone.0251827

In dynamic multisensory environments, the perceptual system corrects for discrepancies arising between modalities. For instance, in the ventriloquism aftereffect (VAE), spatial disparities introduced between visual and auditory stimuli lead to a perc... Read More about Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies.

Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments (2021)
Journal Article
McMaster, D., & Clare, G. (2022). Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments. Disaster Medicine and Public Health Preparedness, 16(4), 1618-1622. https://doi.org/10.1017/dmp.2021.108

Eye health is an integral part of well-being that may be at increased risk when health service delivery is affected by sudden-onset disasters, complex humanitarian events, or conflict in resource-scarce environments. This study proposes a design plan... Read More about Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments.

Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity (2021)
Journal Article
Baxter, L., Moultrie, F., Fitzgibbon, S., Aspbury, M., Mansfield, R., Bastiani, M., …Slater, R. (2021). Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity. Nature Communications, 12, Article 2744. https://doi.org/10.1038/s41467-021-22960-0

Understanding the neurophysiology underlying pain perception in infants is central to improving early life pain management. In this multimodal MRI study, we use resting-state functional and white matter diffusion MRI to investigate individual variabi... Read More about Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity.

European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage (2021)
Journal Article
Sandset, E. C., Anderson, C. S., Bath, P. M., Christensen, H., Fischer, U., Manning, L. S., …Tsivgoulis, G. (2021). European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage. European Stroke Journal, 6(2), XLVIII-LXXXIX. https://doi.org/10.1177/23969873211012133

Introduction: The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and acute intracerebral haemorrhage (ICH) remains controversial. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to as... Read More about European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage.

Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial (2021)
Journal Article
Wang, Y., Claiborne Johnston, S., Bath, P. M., Meng, X., Jing, J., Xie, X., …Li, H. (2021). Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial. Stroke and Vascular Neurology, 6(2), Article e000791. https://doi.org/10.1136/svn-2020-000791

Background: In patients with a minor ischaemic stroke or transient ischaemic attack (TIA), separate trials have shown that dual antiplatelet therapy with clopidogrel plus aspirin (clopidogrel–aspirin) or ticagrelor plus aspirin (ticagrelor–aspirin) a... Read More about Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial.

COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies (2021)
Journal Article
Garjani, A., Middleton, R. M., Hunter, R., Tuite-Dalton, K. A., Coles, A., Dobson, R., …Evangelou, N. (2021). COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies. Multiple Sclerosis and Related Disorders, 52, Article 102939. https://doi.org/10.1016/j.msard.2021.102939

Background Infections can trigger exacerbations of multiple sclerosis (MS). The effects of the coronavirus disease 2019 (COVID-19) on MS are not known. The aim of this study was to understand the impact of COVID-19 on new and pre-existing symptoms... Read More about COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies.

Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences (2021)
Journal Article
Elwick, H., Smith, L., Mhizha-Murira, J. R., Topcu, G., Leighton, P., Drummond, A., …Das Nair, R. (2022). Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences. Neuropsychological Rehabilitation, 32(7), 1456-1474 . https://doi.org/10.1080/09602011.2021.1899942

There is a growing consensus that cognitive assessments should form part of routine clinical care in Multiple Sclerosis (MS). However, what remains unclear is which assessments are preferred by “stakeholders” (including people with MS, family members... Read More about Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences.

Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis (2021)
Journal Article
Alcock, H., Moppett, E., & Moppett, I. (2021). Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis. Bone & Joint Open, 2(5), 314-322. https://doi.org/10.1302/2633-1462.25.BJO-2020-0183.R1

Aims Hip fracture is a common condition of the older, frailer person. This population is also at risk from SARS-CoV-2 infection. It is important to understand the impact of coexistent hip fracture and SARS-CoV-2 for informed decision-making at patie... Read More about Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis.