Outputs (1067)

Decentralised clinical trials in multiple sclerosis research (2022)
Journal Article
Garjani, A., Liu, B. J., Allen, C. M., Gunzler, D. D., Gerry, S. W., Planchon, S. M., …Evangelou, N. (2023). Decentralised clinical trials in multiple sclerosis research. Multiple Sclerosis Journal, 29(3), 317-325. https://doi.org/10.1177/13524585221100401

Randomised controlled trials (RCTs) play an important role in multiple sclerosis (MS) research, ensuring that new interventions are safe and efficacious before their introduction into clinical practice. Trials have been evolving to improve the robust... Read More about Decentralised clinical trials in multiple sclerosis research.

Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol (2022)
Journal Article
Feng, W., Qin, C., Abdelrazig, S., Bai, Z., Raji, M., Darwish, R., …Gershkovich, P. (2022). Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol. International Journal of Pharmaceutics, 624, Article 121947. https://doi.org/10.1016/j.ijpharm.2022.121947

Although natural sesame oil has been shown to facilitate the lymphatic delivery and oral bioavailability of the highly lipophilic drug cannabidiol (CBD), considerable variability remains an unresolved challenge. Vegetable oils differ substantially in... Read More about Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol.

Time Course for Benefit and Risk with Ticagrelor and Aspirin in Individuals with Acute Ischemic Stroke or Transient Ischemic Attack Who Carry CYP2C19 Loss-of-Function Alleles: A Secondary Analysis of the CHANCE-2 Randomized Clinical Trial (2022)
Journal Article
Pan, Y., Meng, X., Jin, A., Johnston, S. C., Li, H., Bath, P. M., …Wang, Y. (2022). Time Course for Benefit and Risk with Ticagrelor and Aspirin in Individuals with Acute Ischemic Stroke or Transient Ischemic Attack Who Carry CYP2C19 Loss-of-Function Alleles: A Secondary Analysis of the CHANCE-2 Randomized Clinical Trial. JAMA Neurology, https://doi.org/10.1001/jamaneurol.2022.1457

Importance: Dual antiplatelet therapy (DAPT) with ticagrelor and aspirin has been found to be effective for secondary prevention after minor ischemic stroke or transient ischemic attack (TIA) in individuals who carry CYP2C19 loss-of-function (LOF) al... Read More about Time Course for Benefit and Risk with Ticagrelor and Aspirin in Individuals with Acute Ischemic Stroke or Transient Ischemic Attack Who Carry CYP2C19 Loss-of-Function Alleles: A Secondary Analysis of the CHANCE-2 Randomized Clinical Trial.

Predicting time-resolved electrophysiological brain networks from structural eigenmodes (2022)
Journal Article
Tewarie, P., Prasse, B., Meier, J., Mandke, K., Warrington, S., Stam, C. J., …Hillebrand, A. (2022). Predicting time-resolved electrophysiological brain networks from structural eigenmodes. Human Brain Mapping, https://doi.org/10.1002/hbm.25967

How temporal modulations in functional interactions are shaped by the underlying anatomical connections remains an open question. Here, we analyse the role of structural eigenmodes, in the formation and dissolution of temporally evolving functional b... Read More about Predicting time-resolved electrophysiological brain networks from structural eigenmodes.

Resting-state functional connectivity correlates of anxiety co-morbidity in major depressive disorder (2022)
Journal Article
Briley, P. M., Webster, L., Boutry, C., Cottam, W. J., Auer, D. P., Liddle, P. F., & Morriss, R. (2022). Resting-state functional connectivity correlates of anxiety co-morbidity in major depressive disorder. Neuroscience and Biobehavioral Reviews, 138, Article 104701. https://doi.org/10.1016/j.neubiorev.2022.104701

Major depressive disorder (MDD) is frequently co-morbid with anxiety disorders. The co-morbid state has poorer functional outcomes and greater resistance to first line treatments, highlighting the need for novel treatment targets. This systematic rev... Read More about Resting-state functional connectivity correlates of anxiety co-morbidity in major depressive disorder.

The Developing Human Connectome Project Neonatal Data Release (2022)
Journal Article
Edwards, A. D., Rueckert, D., Smith, S. M., Seada, S. A., Alansary, A., Almalbis, J., …Hajnal, J. V. (2022). The Developing Human Connectome Project Neonatal Data Release. Frontiers in Neuroscience, 16, Article 886772. https://doi.org/10.3389/fnins.2022.886772

The Developing Human Connectome Project has created a large open science resource which provides researchers with data for investigating typical and atypical brain development across the perinatal period. It has collected 1228 multimodal magnetic res... Read More about The Developing Human Connectome Project Neonatal Data Release.

Cogmed training does not generalise to real-world benefits for adult hearing aid users: results of a blinded, active-controlled randomised trial (2022)
Journal Article
Henshaw, H., Heinrich, A., Tittle, A., & Ferguson, M. (2022). Cogmed training does not generalise to real-world benefits for adult hearing aid users: results of a blinded, active-controlled randomised trial. Ear and Hearing, 43(3), 741-763. https://doi.org/10.1097/AUD.0000000000001096

Objectives: Performance on working memory tasks is positively associated with speech-in-noise perception performance, particularly where auditory inputs are degraded. It is suggested that interventions designed to improve working memory capacity may... Read More about Cogmed training does not generalise to real-world benefits for adult hearing aid users: results of a blinded, active-controlled randomised trial.

A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram (2022)
Journal Article
Jafari, Z., Baguley, D., Kolb, B. E., & Mohajerani, M. H. (2022). A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram. Ear and Hearing, 43(6), 1643-1652. https://doi.org/10.1097/AUD.0000000000001229

OBJECTIVES: Current evidence supports the growing application of extended high-frequency (EHF: 9 to 20 kHz) audiometry in hearing research, which likely results from the high vulnerability of this frequency region to damage induced by known auditory... Read More about A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram.

Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis (2022)
Journal Article
Thompson, B., Moghaddam, N., Evangelou, N., Baufeldt, A., & das Nair, R. (2022). Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders, 63, Article 103862. https://doi.org/10.1016/j.msard.2022.103862

Objective: To review the evidence for the effectiveness of Acceptance and Commitment Therapy (ACT) intervention on quality of life and mood, for individuals with Multiple Sclerosis (MS). Method: A systematic search was conducted of PsycINFO, CINAHL,... Read More about Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis.

Language systems from lesion-symptom mapping in aphasia: A meta-analysis of voxel-based lesion mapping studies (2022)
Journal Article
Na, Y., Jung, J. Y., Tench, C. R., Auer, D. P., & Pyun, S. B. (2022). Language systems from lesion-symptom mapping in aphasia: A meta-analysis of voxel-based lesion mapping studies. NeuroImage: Clinical, 35, Article 103038. https://doi.org/10.1016/j.nicl.2022.103038

Background: Aphasia is one of the most common causes of post-stroke disabilities. As the symptoms and impact of post-stroke aphasia are heterogeneous, it is important to understand how topographical lesion heterogeneity in patients with aphasia is as... Read More about Language systems from lesion-symptom mapping in aphasia: A meta-analysis of voxel-based lesion mapping studies.