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Outputs (1067)

Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study (2023)
Journal Article
Tindall, T., Topcu, G., Thomas, S., Bale, C., Evangelou, N., Drummond, A., & das Nair, R. (2023). Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study. Health Expectations, 26(2), 858-868. https://doi.org/10.1111/hex.13711

Background: Diagnosing multiple sclerosis (MS) can be a lengthy process, which can impact psychological wellbeing, condition management, and future engagement with health services. Therefore, providing timely and appropriate emotional support may imp... Read More about Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study.

MRI assessment of cerebral perfusion in clinical trials (2023)
Journal Article
Wang, X., Bishop, C., O'Callaghan, J., Gayhoor, A., Albani, J., Theriault, W., …Becerra, L. (2023). MRI assessment of cerebral perfusion in clinical trials. Drug Discovery Today, 28(4), Article 103506. https://doi.org/10.1016/j.drudis.2023.103506

Neurodegenerative mechanisms affect the brain through a variety of processes that are reflected as changes in brain structure and physiology. Although some biomarkers for these changes are well established, others are at different stages of developme... Read More about MRI assessment of cerebral perfusion in clinical trials.

The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review (2023)
Journal Article
Phillips, O., Baguley, D., Pearson, S., & Akeroyd, M. A. (2023). The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review. Journal of Cancer Survivorship, 17(1), 40-58. https://doi.org/10.1007/s11764-022-01314-9

Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT). Methods: A literature search was conducted between March and June 2022 u... Read More about The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.

COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes (2023)
Journal Article
Tulloch, J. S., Lawrenson, K., Gordon, A. L., Ghebrehewet, S., Ashton, M., Peddie, S., & Parvulescu, P. (2023). COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes. Vaccine, 41(7), 1290-1294. https://doi.org/10.1016/j.vaccine.2023.01.009

Uptake of COVID-19 vaccine first doses in UK care homes has been higher among residents compared to staff. We aimed to identify causes of lower COVID-19 vaccine uptake amongst care home staff within Liverpool. An anonymised online survey was distribu... Read More about COVID-19 vaccine hesitancy in care home staff: A survey of Liverpool care homes.

Key design elements of successful acute ischemic stroke treatment trials (2023)
Journal Article
Yperzeele, L., Shoamanesh, A., Venugopalan, Y. V., Chapman, S., Mazya, M. V., Charalambous, M., …Koltsov, I. (2023). Key design elements of successful acute ischemic stroke treatment trials. Neurological Research and Practice, 5(1), Article 1. https://doi.org/10.1186/s42466-022-00221-9

Purpose: We review key design elements of positive randomized controlled trials (RCTs) in acute ischemic stroke (AIS) treatment and summarize their main characteristics. Method: We searched Medline, Pubmed and Cochrane databases for positive RCTs in... Read More about Key design elements of successful acute ischemic stroke treatment trials.

Genotype-Guided Dual Antiplatelet Use for Transient Ischemic Attack and Minor Stroke by Imaging Status: Subgroup Analysis of the CHANCE-2 Trial (2022)
Journal Article
Jing, J., Xie, X., Johnston, S. C., Bath, P. M., Li, Z., Zhao, X., …for the CHANCE‐2 Investigators. (2023). Genotype-Guided Dual Antiplatelet Use for Transient Ischemic Attack and Minor Stroke by Imaging Status: Subgroup Analysis of the CHANCE-2 Trial. Annals of Neurology, 93(4), 783-792. https://doi.org/10.1002/ana.26589

Objective: This study was performed to investigate whether ticagrelor/aspirin versus clopidogrel/aspirin can further reduce the residual risk of stroke recurrence in patients with positive diffusion-weighted imaging (DWI) in the High-Risk Patients wi... Read More about Genotype-Guided Dual Antiplatelet Use for Transient Ischemic Attack and Minor Stroke by Imaging Status: Subgroup Analysis of the CHANCE-2 Trial.

Timing of head turns to upcoming talkers in triadic conversation: Evidence for prediction of turn ends and interruptions (2022)
Journal Article
Hadley, L. V., & Culling, J. F. (2022). Timing of head turns to upcoming talkers in triadic conversation: Evidence for prediction of turn ends and interruptions. Frontiers in Psychology, 13, Article 1061582. https://doi.org/10.3389/fpsyg.2022.1061582

In conversation, people are able to listen to an utterance and respond within only a few hundred milliseconds. It takes substantially longer to prepare even a simple utterance, suggesting that interlocutors may make use of predictions about when the... Read More about Timing of head turns to upcoming talkers in triadic conversation: Evidence for prediction of turn ends and interruptions.

Dementia and hearing-aid use: a two-way street (2022)
Journal Article
Naylor, G., Dillard, L., Orrell, M., Stephan, B. C. M., Zobay, O., & Saunders, G. H. (2022). Dementia and hearing-aid use: a two-way street. Age and Ageing, 51(12), Article afac266. https://doi.org/10.1093/ageing/afac266

Objectives Hearing-aid use may reduce risk of dementia, but cognitive impairment makes use more challenging. An observed association between reduced hearing-aid use and incident dementia could reflect either or both of these causal paths. The object... Read More about Dementia and hearing-aid use: a two-way street.

Ticagrelor Aspirin vs Clopidogrel Aspirin in CYP2C19 Loss-of-Function Carriers with Minor Stroke or TIA Stratified by Risk Profile (2022)
Journal Article
Wang, A., Meng, X., Tian, X., Zuo, Y., Bath, P. M., Li, H., …Wang, Y. (2023). Ticagrelor Aspirin vs Clopidogrel Aspirin in CYP2C19 Loss-of-Function Carriers with Minor Stroke or TIA Stratified by Risk Profile. Neurology, 100(5), e497-e504. https://doi.org/10.1212/WNL.0000000000201454

Background and ObjectiveGenotype data of the Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) trial showed that efficacy of clopidogrel aspirin depended on CYP2C19 genotype and risk profile. A stratification of pat... Read More about Ticagrelor Aspirin vs Clopidogrel Aspirin in CYP2C19 Loss-of-Function Carriers with Minor Stroke or TIA Stratified by Risk Profile.