Outputs (63)

Education of family members to support weaning to solids and nutrition in later infancy in term-born infants (2020)
Journal Article
Ojha, S., Elfzzani, Z., Kwok, T. C., & Dorling, J. (2020). Education of family members to support weaning to solids and nutrition in later infancy in term-born infants. Cochrane Database of Systematic Reviews, 2020(7), Article CD012241. https://doi.org/10.1002/14651858.cd012241.pub2

Review question

We reviewed the evidence for effects of nutrition education about appropriate feeding practices during weaning on growth and development in children born at term gestation.

Background

Around the world, over 150 million childr... Read More about Education of family members to support weaning to solids and nutrition in later infancy in term-born infants.

Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations (2020)
Journal Article
Morris, B., Curtin, L., Hawkins-Daarud, A., Hubbard, M. E., Rahman, R., Smith, S. J., Auer, D., Tran, N. L., Hu, L. S., Eschbacher, J. M., Smith, K. A., Stokes, A., Swanson, K. R., & Owen, M. R. (2020). Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations. Mathematical Biosciences and Engineering, 17(5), 4905-4941. https://doi.org/10.3934/mbe.2020267

Glioblastomas (GBMs) are the most aggressive primary brain tumours and have no known cure. Each individual tumour comprises multiple sub-populations of genetically-distinct cells that may respond differently to targeted therapies and may contribute t... Read More about Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations.

Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review. (2020)
Other
Marsh, R. J., Ng, C., Major, G., Rivett, D. W., Smyth, A. R., & Gast, C. V. D. Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review

Background Patients with cystic fibrosis (CF) are characterised by abnormalities of the intestinal tract relating to gut motility and physiological issues, with daily symptoms of disease including abdominal pain, flatulence, bloating, and constipatio... Read More about Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review..

Extraction of Lipids from Liquid Biological Samples for High-Throughput Lipidomics (2020)
Journal Article
Furse, S., Watkins, A. J., & Koulman, A. (2020). Extraction of Lipids from Liquid Biological Samples for High-Throughput Lipidomics. Molecules, 25(14), Article 3192. https://doi.org/10.3390/molecules25143192

Extraction of the lipid fraction is a key part of acquiring lipidomics data. High-throughput lipidomics, the extraction of samples in 96w plates that are then run on 96 or 384w plates, has particular requirements that mean special development work is... Read More about Extraction of Lipids from Liquid Biological Samples for High-Throughput Lipidomics.

Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential (2020)
Journal Article
Smith, S. J., Rowlinson, J., Estevez-Cebrero, M., Onion, D., Ritchie, A., Clarke, P., Wood, K., Diksin, M., Lourdusamy, A., Grundy, R. G., & Rahman, R. (2020). Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential. Neuro-Oncology Advances, 2(1), Article vdaa087. https://doi.org/10.1093/noajnl/vdaa087

Background
Glioblastoma (GBM) is a highly aggressive brain tumor with rapid subclonal diversification, harboring molecular abnormalities that vary temporo-spatially, a contributor to therapy resistance. Fluorescence guided neurosurgical resection ut... Read More about Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential.

NF1 optic pathway glioma. Analysing risk factors for visual outcome and indications to treat (2020)
Journal Article
Azizi, A. A., Walker, D. A., Liu, J.-F., Sehested, A., Jaspan, T., Pemp, B., Simmons, I., Ferner, R., Grill, J., Hargrave, D., Driever, P. H., Evans, D. G., & Opocher, E. (2021). NF1 optic pathway glioma. Analysing risk factors for visual outcome and indications to treat. Neuro-Oncology, 23(1), 100-111. https://doi.org/10.1093/neuonc/noaa153

Background
The aim of the project was to identify risk factors associated with visual progression and treatment indications in pediatric patients with Neurofibromatosis type 1 associated optic pathway gliomas (NF1-OPG).

Methods
A multi-disciplin... Read More about NF1 optic pathway glioma. Analysing risk factors for visual outcome and indications to treat.

A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups (2020)
Journal Article
Ritzmann, T. A., Rogers, H. A., Paine, S. M., Storer, L. C., Jacques, T. S., Chapman, R. J., Ellison, D., Donson, A. M., Foreman, N. K., & Grundy, R. G. (2020). A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups. Pediatric Blood and Cancer, 67(9), Article e28426. https://doi.org/10.1002/pbc.28426

Background: Relapse occurs in 50% of pediatric ependymoma cases and has poor prognosis. Few studies have investigated the clinical progress of relapsed disease, and treatment lacks a standardized approach. Methods and materials: We analyzed 302 pedia... Read More about A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups.

Timing and mode of delivery with advancing maternal age (2020)
Journal Article
Walker, K. F., & Thornton, J. G. (2021). Timing and mode of delivery with advancing maternal age. Best Practice and Research: Clinical Obstetrics and Gynaecology, 70, 101-111. https://doi.org/10.1016/j.bpobgyn.2020.06.005

In 2017, 23% of all live births in the United Kingdom were to women aged over 35 years. Decisions around the timing of delivery for such women must balance the risks of prolongation of the pregnancy and of iatrogenic harm from timed delivery. Women o... Read More about Timing and mode of delivery with advancing maternal age.

Antimicrobial resistance: Concerns of healthcare providers and people with CF (2020)
Journal Article
Bullington, W., Hempstead, S., Smyth, A. R., Drevinek, P., Saiman, L., Waters, V. J., Bell, S. C., VanDevanter, D. R., Flume, P. A., Elborn, S., Muhlebach, M. S., & Antimicrobial Resistance International Working Group in Cystic Fibrosis. (2021). Antimicrobial resistance: Concerns of healthcare providers and people with CF. Journal of Cystic Fibrosis, 20(3), 407-412. https://doi.org/10.1016/j.jcf.2020.05.009

Background
Chronic lung infections and their treatment pose risks for the development of antimicrobial resistance (AMR) in people with cystic fibrosis (PWCF). In this study, we evaluated the attitudes of healthcare providers’ (HCP) and PWCF or their... Read More about Antimicrobial resistance: Concerns of healthcare providers and people with CF.

Maternal, fetal and placental selectins in women with pre-eclampsia: association with the renin-angiotensin-system (2020)
Journal Article
Mistry, H. D., Ogalde, M. V. H., Pipkin, F. B., Escher, G., & Kurlak, L. O. (2020). Maternal, fetal and placental selectins in women with pre-eclampsia: association with the renin-angiotensin-system. Frontiers in Medicine, 7, Article 270. https://doi.org/10.3389/fmed.2020.00270

Selectins [endothelial (E), platelet (P), and leucocytes (L)] are a class of cell adhesion molecules, stimulated in response to inflammation. Pre-eclampsia is characterized by inflammation, and angiotensin II is pro-inflammatory. We hypothesized that... Read More about Maternal, fetal and placental selectins in women with pre-eclampsia: association with the renin-angiotensin-system.