Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function
(2014)
Journal Article
Chen, L., Tang, W., Kowgier, M., Loth, D. W., Soler Artigas, M., Joubert, B. R., Hodge, E., Gharib, S. A., Smith, A. V., Ruczinski, I., Gudnason, V., Mathias, R. A., Harris, T. B., Hansel, N. N., Launer, L. J., Barnes, K. C., Hansen, J. G., Albrecht, E., Aldrich, M. C., Allerhand, M., …Cassano, P. A. (2014). Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function. PLoS ONE, 9(7), Article e100776. https://doi.org/10.1371/journal.pone.0100776
Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.
Methods: We performed GWAS of the rate of cha...
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