Outputs (4)

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) (2018)
Journal Article
Chalmers, J., Thomas, K., Apfelbacher, C., Williams, H., Prinsen, C., Spuls, P., Simpson, E., Gerbens, L., Boers, M., Barbarot, S., Stalder, J., Abuabara, K., Aoki, V., Ardeleanu, M., Armstrong, J., Bang, B., Berents, T., Burton, T., Butler, L., Chubachi, T., …Zaniboni, M. (2018). Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative). British Journal of Dermatology, 178(5), e332-e341. https://doi.org/10.1111/bjd.16543

This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus... Read More about Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).

What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials (2016)
Journal Article
Nankervis, H., Thomas, K., Delamere, F. M., Barbarot, S., Smith, S., Rogers, N. K., & Williams, H. C. (in press). What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials. British Journal of Dermatology, 176(4), https://doi.org/10.1111/bjd.14999

Atopic eczema (AE) is a common chronic inflammatory skin condition. Whilst many AE treatment options are available, the evidence to support their efficacy varies in depth and quality. In 2000, an NIHR HTA systematic review identified and evaluated ex... Read More about What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials.

Scoping systematic review of treatments for eczema (2016)
Journal Article
Nankervis, H., Thomas, K., Delamere, F. M., Barbarot, S., Rogers, N. K., & Williams, H. C. (2016). Scoping systematic review of treatments for eczema. Programme Grants for Applied Research, 4(7), https://doi.org/10.3310/pgfar04070

Background: Eczema is a very common chronic inflammatory skin condition.
Objectives: To update the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) systematic review of treatments for atopic eczema, published in 2000,... Read More about Scoping systematic review of treatments for eczema.

Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration (2010)
Journal Article
Rogers, N., Paine, S., Bedford, L., & Layfield, R. (2010). Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration. Neuropathology and Applied Neurobiology, 36(2), 113-124. https://doi.org/10.1111/j.1365-2990.2010.01063.x

The significance of the accumulation of ubiquitin-positive intraneuronal inclusions in the brains of those affected with different neurodegenerative diseases is currently unclear. While one interpretation is that the disease mechanism(s) involves dys... Read More about Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration.