Outputs (4)

An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks (2019)
Journal Article
Belfield, K., Chen, X., Smith, E. F., Ashraf, W., & Bayston, R. (2019). An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks. Acta Biomaterialia, 90, 157-168. https://doi.org/10.1016/j.actbio.2019.03.042

Two major complications of indwelling urinary catheterisation include infection and mineral encrustation of the catheter. Our antimicrobial urinary catheter (AUC) impregnated with rifampicin, triclosan, and sparfloxacin has demonstrated long-term pro... Read More about An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks.

A tolerability and patient acceptability pilot study of a novel antimicrobial urinary catheter for long-term use (2018)
Journal Article
Belfield, K., Betts, H., Parkinson, R., & Bayston, R. (2018). A tolerability and patient acceptability pilot study of a novel antimicrobial urinary catheter for long-term use. Neurourology and Urodynamics, 38(1), 338-345. https://doi.org/10.1002/nau.23858

© 2018 Wiley Periodicals, Inc. Aims: We have developed a novel antimicrobial urinary catheter (AUC) impregnated with rifampicin, triclosan, and sparfloxacin and demonstrated that it has long-term (∼84 days) protection against bacterial colonization i... Read More about A tolerability and patient acceptability pilot study of a novel antimicrobial urinary catheter for long-term use.

Evaluation of combinations of putative anti-biofilm agents and antibiotics to eradicate biofilms of Staphylococcus aureus and Pseudomonas aeruginosa (2017)
Journal Article
Belfield, K., Bayston, R., Hajduk, N., Levell, G., Birchall, J. P., & Daniel, M. (2017). Evaluation of combinations of putative anti-biofilm agents and antibiotics to eradicate biofilms of Staphylococcus aureus and Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy, 72(9), 2531-2538. https://doi.org/10.1093/jac/dkx192

Objectives

To evaluate potential anti-biofilm agents for their ability to enhance the activity of antibiotics for local treatment of localized biofilm infections.
Methods

Staphylococcus aureus and Pseudomonas aeruginosa in vitro biofilm models... Read More about Evaluation of combinations of putative anti-biofilm agents and antibiotics to eradicate biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.

Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review (2015)
Journal Article
Belfield, K., Bayston, R., Birchall, J., & Daniel, M. (2015). Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review. International Journal of Pediatric Otorhinolaryngology, 79(3), 296-300. https://doi.org/10.1016/j.ijporl.2015.01.003

INTRODUCTION:
Infectious conditions of the middle ear are a common and significant cause of morbidity and mortality worldwide. Systemic antibiotics are frequently used, but their effectiveness will depend on whether an adequate antibiotic concentrat... Read More about Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review.