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Outputs (557)

The practice of continuous deep sedation until death in Flanders (Belgium), The Netherlands, and the U.K.: a comparative study (2012)
Journal Article
Anquinet, L., Rietjens, J. A., Seale, C., Seymour, J., Deliens, L., & van der Heide, A. (2012). The practice of continuous deep sedation until death in Flanders (Belgium), The Netherlands, and the U.K.: a comparative study. Journal of Pain and Symptom Management, 44(1), https://doi.org/10.1016/j.jpainsymman.2011.07.007

Context:Existing empirical evidence shows that continuous deep sedation until death is given in about 15% of all deaths in Flanders, Belgium (BE), 8% in The Netherlands (NL), and 17% in the U.K.
Objectives:This study compares characteristics of cont... Read More about The practice of continuous deep sedation until death in Flanders (Belgium), The Netherlands, and the U.K.: a comparative study.

Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention (2012)
Journal Article
Morriss, R. K., Kai, J., Atha, C., Avery, A., Bayes, S., Franklin, M., George, T., James, M., Malins, S., McDonald, R., Patel, S., Stubley, M., & Yang, M. (2012). Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention. BMC Family Practice, 13(39), https://doi.org/10.1186/1471-2296-13-39

Background:

The top 3% of frequent attendance in primary care is associated with 15% of all appointments in primary care, a fivefold increase in hospital expenditure, and more mental disorder and functional somatic symptoms compared to normal atte... Read More about Persistent frequent attenders in primary care: costs, reasons for attendance, organisation of care and potential for cognitive behavioural therapeutic intervention.

Genome-wide association study to identify genetic determinants of severe asthma (2012)
Journal Article
Wan, Y., Shrine, N., Soler Artigas, M., Wain, L., Blakey, J., Moffatt, M., Bush, A., Chung, K. F., Cookson, W., Strachan, D., Heaney, L., Al-Momani, B., Mansur, A., Manney, S., Thomson, N., Chaudhuri, R., Brightling, C., Bafadhel, M., Singapuri, A., Niven, R., …Hall, I. P. (2012). Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67(9), https://doi.org/10.1136/thoraxjnl-2011-201262

Background The genetic basis for developing asthma has been extensively studied. However, association studies to date have mostly focused on mild to moderate disease and genetic risk factors for severe asthma remain unclear.
Objective To identify co... Read More about Genome-wide association study to identify genetic determinants of severe asthma.

Using evolutionary algorithms for fitting high-dimensional models to neuronal data (2012)
Journal Article
Svensson, C.-M., Coombes, S., & Peirce, J. (2012). Using evolutionary algorithms for fitting high-dimensional models to neuronal data. Neuroinformatics, 10(2), https://doi.org/10.1007/s12021-012-9140-7

n the study of neurosciences, and of complex biological systems in general, there is frequently a need to fit mathematical models with large numbers of parameters to highly complex datasets. Here we consider algorithms of two different classes, gradi... Read More about Using evolutionary algorithms for fitting high-dimensional models to neuronal data.

Genetic basis for personalized medicine in asthma (2012)
Journal Article
Portelli, M. A., & Sayers, I. (2012). Genetic basis for personalized medicine in asthma. Expert Review of Respiratory Medicine, 6(2), https://doi.org/10.1586/ers.12.9

There is heterogeneity in patient responses to current asthma medications. Significant progress has been made identifying genetic polymorphisms that influence the efficacy and potential for adverse effects to asthma drugs, including; β2-adrenergic re... Read More about Genetic basis for personalized medicine in asthma.

Commentary (2012)
Journal Article
Blake, H. (2012). Commentary. International Journal of Therapy and Rehabilitation, 19(3), 143. https://doi.org/10.12968/ijtr.2012.19.3.143

[This is a commentary on: Tai Chi intervention for older adults using assistive devices in a senior living community: a pilot study (https://www.magonlinelibrary.com/doi/abs/10.12968/ijtr.2012.19.3.136?journalCode=ijtr)]

Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data (2012)
Journal Article
Jansen, M., White, T. P., Mullinger, K. J., Liddle, E. B., Gowland, P. A., Francis, S. T., Bowtell, R. W., & Liddle, P. F. (2012). Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data. NeuroImage, 59(1), https://doi.org/10.1016/j.neuroimage.2011.06.094

The simultaneous acquisition and subsequent analysis of EEG and fMRI data is challenging owing to increased noise levels in the EEG data. A common method to integrate data from these two modalities is to use aspects of the EEG data, such as the ampli... Read More about Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data.

Callers' experiences of contacting a national suicide prevention helpline: report of an online survey (2012)
Journal Article
Coveney, C. M., Pollock, K., Armstrong, S., & Moore, J. (2012). Callers' experiences of contacting a national suicide prevention helpline: report of an online survey. Crisis - The Journal of Crisis Intervention and Suicide Prevention, 33(6), https://doi.org/10.1027/0227-5910/a000151

Background: Helplines are a significant phenomenon in the mixed economy of health and social care. Given the often anonymous and fleeting nature of caller contact, it is difficult to obtain data about their impact and how users perceive their value.... Read More about Callers' experiences of contacting a national suicide prevention helpline: report of an online survey.

Intraoperative portable ultrasonography localization of clinically impalpable soft-tissue tumors (2012)
Journal Article
Jagadeesan, J., Davies, J. A., Raurell, A., & Ashford, R. U. (2012). Intraoperative portable ultrasonography localization of clinically impalpable soft-tissue tumors. World Journal of Surgical Oncology, 10, Article 243. https://doi.org/10.1186/1477-7819-10-243

Background: Most soft-tissue tumors are clinically palpable; however, some can be impalpable to clinical examination making it difficult to plan surgical management.

Methods: We present a simple method of perioperative tumor localization using a p... Read More about Intraoperative portable ultrasonography localization of clinically impalpable soft-tissue tumors.