Outputs (138)

Model-based Bayesian inference of brain oxygenation using quantitative BOLD (2019)
Journal Article
Cherukara, M. T., Stone, A. J., Chappell, M. A., & Blockley, N. P. (2019). Model-based Bayesian inference of brain oxygenation using quantitative BOLD. NeuroImage, 202, Article 116106. https://doi.org/10.1016/j.neuroimage.2019.116106

© 2019 The Authors Streamlined Quantitative BOLD (sqBOLD) is an MR technique that can non-invasively measure physiological parameters including Oxygen Extraction Fraction (OEF) and deoxygenated blood volume (DBV) in the brain. Current sqBOLD methodol... Read More about Model-based Bayesian inference of brain oxygenation using quantitative BOLD.

Mood and influenza vaccination in older adults: A randomized controlled trial. (2019)
Journal Article
Ayling, K., Fairclough, L., Buchanan, H., Wetherell, M. A., & Vedhara, K. (2019). Mood and influenza vaccination in older adults: A randomized controlled trial. Health Psychology, 38(11), 984-996. https://doi.org/10.1037/hea0000786

Objective: Positive mood on the day of vaccination has been associated with subsequent antibody responses to the influenza vaccine in older adults. The primary aim of this trial was to examine whether a brief intervention was able to enhance positive... Read More about Mood and influenza vaccination in older adults: A randomized controlled trial..

Epoxy–amine oligomers from terpenes with applications in synergistic antifungal treatments (2019)
Journal Article
O’Brien, D. M., Vallieres, C., Alexander, C., Howdle, S. M., Stockman, R. A., & Avery, S. V. (2019). Epoxy–amine oligomers from terpenes with applications in synergistic antifungal treatments. Journal of Materials Chemistry B, 7(34), 5222-5229. https://doi.org/10.1039/c9tb00878k

A bis-epoxide monomer was synthesised in two steps from (R)-carvone, a terpenoid renewable feedstock derived from spearmint oil, and used to prepare β-aminoalcohol oligomers in polyaddition reactions with bis-amines without requiring solvent or catal... Read More about Epoxy–amine oligomers from terpenes with applications in synergistic antifungal treatments.

Meta-analysis of goal directed fluid therapy using transoesophageal doppler in patients undergoing elective colorectal surgery (2019)
Journal Article
Rollins, K., Mathias, N., & Lobo, D. (2019). Meta-analysis of goal directed fluid therapy using transoesophageal doppler in patients undergoing elective colorectal surgery. BJS Open, 3(5), 606-616. https://doi.org/10.1002/bjs5.50188

Background: Intraoperative goal-directed fluid therapy (GDFT) is recommended for intraoperative fluid management for elective colorectal surgery in most perioperative guidelines. However, the evidence in elective colorectal surgery alone is not welle... Read More about Meta-analysis of goal directed fluid therapy using transoesophageal doppler in patients undergoing elective colorectal surgery.

Psychological interventions as vaccine adjuvants: A systematic review (2019)
Journal Article
Vedhara, K., Ayling, K., Sunger, K., Caldwell, D. M., Halliday, V., Fairclough, L., Avery, A., Robles, L., Garibaldi, J., Welton, N. J., & Royal, S. (2019). Psychological interventions as vaccine adjuvants: A systematic review. Vaccine, 37(25), 3255-3266. https://doi.org/10.1016/j.vaccine.2019.04.091

Objectives: The effectiveness of vaccines is known to be altered by a range of psychological factors. We conducted a systematic review to evaluate the effects of psychological interventions on the ability of vaccines to protect against disease, as me... Read More about Psychological interventions as vaccine adjuvants: A systematic review.

Pharmacological characterization of a novel 5-hydroxybenzothiazolone-derived b2-adrenoceptor agonist with functional selectivity for anabolic effects on skeletal muscle resulting in a wider cardiovascular safety window in preclinical studies (2019)
Journal Article
Koziczak-Holbro, M., Rigel, D. F., Dumotier, B., Sykes, D. A., Tsao, J., Nguyen, N. H., Bösch, J., Jourdain, M., Flotte, L., Adachi, Y., Kiffe, M., Azria, M., Fairhurst, R. A., Charlton, S. J., Richardson, B. P., Lach-Trifilieff, E., Glass, D. J., Ullrich, T., & Hatakeyama, S. (2019). Pharmacological characterization of a novel 5-hydroxybenzothiazolone-derived b2-adrenoceptor agonist with functional selectivity for anabolic effects on skeletal muscle resulting in a wider cardiovascular safety window in preclinical studies. Journal of Pharmacology and Experimental Therapeutics, 369(2), 188-199. https://doi.org/10.1124/jpet.118.255307

Copyright ª 2019 by The Author(s) The anabolic effects of b2-adrenoceptor (b2-AR) agonists on skeletal muscle have been demonstrated in various species. However, the clinical use of b2-AR agonists for skeletal muscle wasting conditions has been limit... Read More about Pharmacological characterization of a novel 5-hydroxybenzothiazolone-derived b2-adrenoceptor agonist with functional selectivity for anabolic effects on skeletal muscle resulting in a wider cardiovascular safety window in preclinical studies.

Vocal instability over time in individual male European nightjars, Caprimulgus europaeus: recommendations for acoustic monitoring and surveys (2019)
Journal Article
Raymond, S., Spotswood, S., Clarke, H., Zielonka, N., Lowe, A., & Durrant, K. L. (2020). Vocal instability over time in individual male European nightjars, Caprimulgus europaeus: recommendations for acoustic monitoring and surveys. Bioacoustics, 29(3), 280-295. https://doi.org/10.1080/09524622.2019.1603121

Acoustic monitoring of birds is developing rapidly as equipment, methods and analyses improve. However, most population monitoring studies still utilise traditional techniques like mark-recapture or line transects. Rebbeck et al. (2001) used vocal re... Read More about Vocal instability over time in individual male European nightjars, Caprimulgus europaeus: recommendations for acoustic monitoring and surveys.

Heritability and genetic variance of dementia with Lewy bodies (2019)
Journal Article
Guerreiro, R., Escott-Price, V., Hernandez, D., Kun-Rodrigues, C., Ross, O., Orme, T., Neto, J. L., Carmona, S., Dehghani, N., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S., Troncoso, J., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., …Bras, J. (2019). Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease, 127, 492-501. https://doi.org/10.1016/j.nbd.2019.04.004

Recent large-scale genetic studies have allowed for the first glimpse of the effects of common genetic variability in dementia with
Lewy bodies (DLB), identifying risk variants with appreciable effect sizes. However, it is currently well established... Read More about Heritability and genetic variance of dementia with Lewy bodies.

Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics (2019)
Journal Article
Siu-Ting, K., Torres-Sánchez, M., San Mauro, D., Wilcockson, D., Wilkinson, M., Pisani, D., O’Connell, M. J., & Creevey, C. J. (2019). Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics. Molecular Biology and Evolution, 36(6), 1344-1356. https://doi.org/10.1093/molbev/msz067

Increasingly, large phylogenomic datasets include transcriptomic data from non-model organisms. This has allowed controversial and unexplored evolutionary relationships in the tree of life to be addressed but also increases the risk of inadvertent in... Read More about Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics.

Effects of inorganic nitrate and vitamin C co-supplementation on blood pressure and vascular function in younger and older healthy adults: A randomised double-blind crossover trial (2019)
Journal Article
Ashor, A. W., Shannon, O. M., Werner, A.-D., Scialo, F., Gilliard, C. N., Cassel, K. S., Seal, C. J., Zheng, D., Mathers, J. C., & Siervo, M. (2019). Effects of inorganic nitrate and vitamin C co-supplementation on blood pressure and vascular function in younger and older healthy adults: A randomised double-blind crossover trial. Clinical Nutrition, https://doi.org/10.1016/j.clnu.2019.03.006

© 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Background: Vitamin C and inorganic nitrate have been linked to enhanced nitric oxide (NO) production and reduced oxidative stress. Vitamin C may also enhance the conversi... Read More about Effects of inorganic nitrate and vitamin C co-supplementation on blood pressure and vascular function in younger and older healthy adults: A randomised double-blind crossover trial.