Diazophosphonates: Effective Surrogates for Diazoalkanes in Pyrazole Synthesis
(2021)
Journal Article
Ruffell, K., Smith, F. R., Green, M. T., Nicolle, S. M., Inman, M., Lewis, W., Hayes, C. J., & Moody, C. J. (2021). Diazophosphonates: Effective Surrogates for Diazoalkanes in Pyrazole Synthesis. Chemistry - A European Journal, 27(55), 13703-13708. https://doi.org/10.1002/chem.202101788
Diazophosphonates, readily prepared from -ketophosphonates by oxidation of the corresponding hydrazones in batch or in flow, are useful partners in 1,3-dipolar cycloaddition reactions to alkynes to give N-H pyrazoles, including the first intramolecu... Read More about Diazophosphonates: Effective Surrogates for Diazoalkanes in Pyrazole Synthesis.