Dr SARAH BLOTT's Outputs (3)

Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis (2022)
Journal Article
Tengvall, K., Sundström, E., Wang, C., Bergvall, K., Wallerman, O., Pederson, E., Karlsson, Å., Harvey, N. D., Blott, S. C., Olby, N., Olivry, T., Brander, G., Meadows, J. R. S., Roosje, P., Leeb, T., Hedhammar, Å., Andersson, G., & Lindblad-Toh, K. (2022). Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis. Communications Biology, 5(1), Article 1348. https://doi.org/10.1038/s42003-022-04279-8

Canine atopic dermatitis is an inflammatory skin disease with clinical similarities to human atopic dermatitis. Several dog breeds are at increased risk for developing this disease but previous genetic associations are poorly defined. To identify add... Read More about Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis.

Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes (2022)
Journal Article
Schrurs, C., Blott, S., Dubois, G., Van Erck-Westergren, E., & Gardner, D. S. (2022). Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes. Animals, 12(23), Article 3269. https://doi.org/10.3390/ani12233269

Racehorses competing in short (i.e., ‘sprinters’), middle- or longer-distance (i.e., ‘stayers’) flat races are assumed to have natural variation in locomotion; sprinters having an innately shorter stride than stayers. No study has objectively tested... Read More about Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes.

GIFT: New method for the genetic analysis of small gene effects involving small sample sizes (2022)
Journal Article
Rauch, C., Kyratzi, P., Blott, S., Bray, S., & Wattis, J. A. D. (2023). GIFT: New method for the genetic analysis of small gene effects involving small sample sizes. Physical Biology, 20(1), Article 016001. https://doi.org/10.1088/1478-3975/ac99b3

Small gene effects involved in complex/omnigenic traits remain costly to analyse using current genome-wide association methods (GWAS) because of the number of individuals required to return meaningful association(s), a.k.a. study power. Inspired by f... Read More about GIFT: New method for the genetic analysis of small gene effects involving small sample sizes.