Skip to main content

Research Repository

Advanced Search

Outputs (95)

Prevalence, regional patterns and socio-demographic factors associated with poly-tobacco use in India: A secondary data analysis (2024)
Journal Article
Bantwal, P., Kulkarni, M. M., Kamath, V. G., Naik, A. K., Fogarty, A. W., Dhar, M., & Ahankari, A. S. (2024). Prevalence, regional patterns and socio-demographic factors associated with poly-tobacco use in India: A secondary data analysis. PLOS Global Public Health, 4(3), Article e0002999. https://doi.org/10.1371/journal.pgph.0002999

Background: Tobacco use is associated with early, intermediate and long-term complications throughout the life course. With an influx of newer products containing nicotine, poly-tobacco use is slowly emerging as a public health concern, that is defin... Read More about Prevalence, regional patterns and socio-demographic factors associated with poly-tobacco use in India: A secondary data analysis.

The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study (2024)
Journal Article
Alothman, D., Lewis, S., Card, T., Tyrrell, E., & Fogarty, A. W. (2024). The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study. Journal of Affective Disorders, 352, 278-280. https://doi.org/10.1016/j.jad.2024.02.047

Background: Social isolation is a potentially reversible risk factor for suicide. Methods: A matched case control study design was used. The study population was from England and identified from an electronic primary case database with linkage to a s... Read More about The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study.

Prospective study of exposure to smoking imagery in films and changes in susceptibility to smoking in a cohort of school students in Southern India (2024)
Journal Article
Kamath, V. G., Kulkarni, M. M., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (in press). Prospective study of exposure to smoking imagery in films and changes in susceptibility to smoking in a cohort of school students in Southern India. Tobacco Induced Diseases,

Background: India has unique tobacco-free film and TV rules designed to prevent tobacco uptake. In this study, we examined the potential influence of exposure to smoking imagery in regionally famous films on teenagers enrolled in schools in a distric... Read More about Prospective study of exposure to smoking imagery in films and changes in susceptibility to smoking in a cohort of school students in Southern India.

Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England (2023)
Journal Article
Alothman, D., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. W. (2023). Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England. The Lancet Regional Health Europe, 32, Article 100695. https://doi.org/10.1016/j.lanepe.2023.100695

Background: Analgesics prescriptions may provide a marker for identifying individuals at higher risk of suicide. In particular, awareness of which analgesics are implicated may help clinicians assess and modify risk. Method: A case–control study in E... Read More about Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England.

Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis (2023)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis. Respiratory Physiology and Neurobiology, 315, Article 104098. https://doi.org/10.1016/j.resp.2023.104098

Objective To explore the associations between arterial pO2, pCO2 and pH and how these are modified by age. Methods An analysis of 2598 patients admitted with a diagnosis of Covid-19 infection to a large UK teaching hospital. Results There we... Read More about Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis.

Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection (2023)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection. Clinical Medicine, 23(3), 201-205. https://doi.org/10.7861/clinmed.2022-0436

AIMS: The study tests the hypothesis that a higher acute systemic inflammatory response was associated with a larger decrease in blood hemoglobin levels in patients with Coronavirus 2019 (COVID-19) infection. METHODS: All patients with either suspect... Read More about Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection.

Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia (2023)
Journal Article
Hirpa, S., Fogarty, A. W., Addissie, A., Bauld, L., Frese, T., Unverzagt, S., …Deressa, W. (2023). Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia. BMC Public Health, 23, Article 226. https://doi.org/10.1186/s12889-023-15088-x

Background: Tobacco, khat, alcohol and marijuana are the main risk factors for non-communicable diseases. There are limited studies on substance use in Ethiopia, especially among secondary school students. This study aims to determine the epidemiol... Read More about Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia.

Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection. Emergency Medicine Journal, 40(3), 216-220. https://doi.org/10.1136/emermed-2022-212443

Background Pulse oximeters are a standard non-invasive tool to measure blood oxygen levels, and are used in multiple healthcare settings. It is important to understand the factors affecting their accuracy to be able to use them optimally and safely.... Read More about Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection.

Risk of Suicide After Dementia Diagnosis (2022)
Journal Article
Alothman, D., Card, T., Lewis, S., Tyrrell, E., Fogarty, A. W., & Marshall, C. R. (2022). Risk of Suicide After Dementia Diagnosis. JAMA Neurology, 79(11), 1148-1154. https://doi.org/10.1001/jamaneurol.2022.3094

Importance: Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives: To examine the association between a d... Read More about Risk of Suicide After Dementia Diagnosis.

Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units. QJM: An International Journal of Medicine, 116(1), 63-67. https://doi.org/10.1093/qjmed/hcac218

Summary Background Pulse oximeters are widely used to monitor blood oxygen saturations, although concerns exist that they are less accurate in individuals with pigmented skin. Aims This study aimed to determine if patients with pigmented skin were mo... Read More about Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units.

Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (2022)
Journal Article
Crooks, C. J., West, J., Fogarty, A., Morling, J. R., Grainge, M. J., Gonem, S., …Card, T. R. (2022). Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2. American Journal of Epidemiology, 191(11), 1944-1953. https://doi.org/10.1093/aje/kwac126

We compared the performance of prognostic tools for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using parameters fitted either at the time of hospital admission or across all time points of an admission. This cohort study used clinic... Read More about Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2.

Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. (2022). Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection. Clinical Medicine, 22(3), 192-196. https://doi.org/10.7861/clinmed.2021-0603

Objective To determine the maximal response of the temperature and inflammatory response to SARS-CoV-2 infection and how these are modified by age. Methods Participants were patients admitted to hospital with SARS-CoV-2 infection. For each partici... Read More about Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection.

Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection (2022)
Journal Article
Plummer, N. R., Fogarty, A., Shaw, D., Card, T., West, J., & Crooks, C. (2022). Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection. Respiratory Medicine, 197, Article 106858. https://doi.org/10.1016/j.rmed.2022.106858

Background: We aimed to assess whether asymptomatic (“happy”) hypoxia was an identifiable physiological phenotype of COVID-19 acute respiratory distress syndrome (ARDS), and associated with need for ICU admission. Methods: We performed an observation... Read More about Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection.

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article
Alothman, D., Marshall, C. R., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. (2022). Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England. Journal of Neurology, 269, 4436–4439. https://doi.org/10.1007/s00415-022-11085-z

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.

Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India (2022)
Journal Article
Kulkarni, M. M., Kamath, V. G., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (2022). Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India. Nicotine and Tobacco Research, 24(7), 1104-1109. https://doi.org/10.1093/ntr/ntac003

Introduction: Although most of the disease burden is due to tobacco smoking, smokeless tobacco (SLT) use contributed to an estimated 76,000 deaths in 2017. We have studied the potential risk factors for SLT use among adolescents in South India. M... Read More about Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India.

The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia (2022)
Journal Article
Tamire, M., Barker, A., Getachew, S., Murray, R. L., Amedala, R., Britton, J., …Fogarty, A. W. (2022). The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia. Harm Reduction Journal, 19, Article 11. https://doi.org/10.1186/s12954-022-00591-y

Background: Excessive alcohol consumption is an important risk factor for increased morbidity, mortality and other social harms globally. Televised sport allows the promotion of alcoholic drinks to a large and often young audience, and thus can be us... Read More about The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia.

Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis (2022)
Journal Article
Webb, K., Zain, N. M. M., Stewart, I., Fogarty, A., Nash, E. F., Whitehouse, J. L., …Barr, H. L. (2022). Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis. Journal of Medical Microbiology, 71(2), Article 001481. https://doi.org/10.1099/jmm.0.001481

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum... Read More about Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.

Ethnicity and suicide risk: A population-based study from England (2021)
Journal Article
Alothman, D., Fogarty, A., Tyrrell, E., Lewis, S., & Card, T. (2022). Ethnicity and suicide risk: A population-based study from England. Journal of Affective Disorders, 298(Part A), 555-557. https://doi.org/10.1016/j.jad.2021.11.044

Using multiple linked electronic health databases, we conducted a large case-control study in England from 2001 through 2019 to examine the association between ethnicity and suicide risk. Asian, Black and Other ethnic groups had a significantly lower... Read More about Ethnicity and suicide risk: A population-based study from England.

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis (2021)
Journal Article
Zain, N. M. M., Webb, K., Stewart, I., Halliday, N., Barrett, D. A., Nash, E. F., …Barr, H. L. (2021). 2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis. Journal of Medical Microbiology, 70(10), https://doi.org/10.1099/jmm.0.001420

Introduction. Pseudomonas aeruginosa produces quorum sensing signalling molecules including 2-alkyl-4-quinolones (AQs), which regulate virulence factor production in the cystic fibrosis (CF) airways. Hypothesis/Gap statement. Culture can lead to cond... Read More about 2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis.

Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19 (2021)
Journal Article
Au-Yong, I., Higashi, Y., Giannotti, E., Fogarty, A., Morling, J. R., Grainge, M., …Card, T. (2022). Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology, 302(2), 460-469. https://doi.org/10.1148/radiol.2021210986

Background Radiographic severity may help predict patient deterioration and outcomes from COVID-19 pneumonia. Purpose To assess the reliability and reproducibility of three chest radiograph reporting systems (radiographic assessment of lung edema [RA... Read More about Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19.

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis (2021)
Journal Article
Webb, K., Cámara, M., Zain, N. M. M., Halliday, N., Bruce, K. D., Nash, E. F., …Barr, H. L. (2022). Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis. Journal of Cystic Fibrosis, 21(4), 626-629. https://doi.org/10.1016/j.jcf.2021.08.030

Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det... Read More about Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.

Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India (2021)
Journal Article
Kulkarni, M. M., Kamath, A., Kamath, V. G., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (2021). Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India. PLoS ONE, 16(8), Article e0253593. https://doi.org/10.1371/journal.pone.0253593

Background Exposure to tobacco imagery in films causes young people to start smoking. Popular Indian films contain high levels of tobacco imagery, but those that do are required by law to display onscreen health warnings when smoking imagery occurs a... Read More about Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India.

An Emerging Problem of Shisha Smoking among High School Students in Ethiopia (2021)
Journal Article
Hirpa, S., Fogarty, A., Addissie, A., Bauld, L., Frese, T., Unverzagt, S., …Deressa, W. (2021). An Emerging Problem of Shisha Smoking among High School Students in Ethiopia. International Journal of Environmental Research and Public Health, 18(13), Article 7023. https://doi.org/10.3390/ijerph18137023

Shisha smoking is also known as hookah, water pipe, goza, and nargile. Shisha use among the young is increasing globally. Shisha smoke results in a high concentration of carbon monoxide, tar, nicotine, and heavy metals which can be toxic to humans, e... Read More about An Emerging Problem of Shisha Smoking among High School Students in Ethiopia.

Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades (2021)
Journal Article
Suárez-Medina, R., Venero-Fernández, S., Mesa Ridel, G., Fogarty, A., & Lewis, S. (2021). Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades. Public Health, 191, 55-58. https://doi.org/10.1016/j.puhe.2020.11.022

Objectives The objective of this study is to understand how Cuba responds to extreme weather events, which can help identify and disseminate good public health practice. Study design The study design of this study is an observational study u... Read More about Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades.

Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety (2020)
Journal Article
Thurley, P., Bowker, R., Bhatti, I., Skelly, R., Law, R., Salaman, R., …Fogarty, A. (2020). Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety. BMJ Open Quality, 9(4), Article e000900. https://doi.org/10.1136/bmjoq-2019-000900

Background Over recent decades, CT scans have become routinely available and are used in both acute medical and outpatient environments. However, there is a small increase in the risk of adverse consequences, including an increase in the risk of both... Read More about Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety.

Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study (2020)
Journal Article
Ahankari, A., Kabra, P., Tata, L., Hayter, M., & Fogarty, A. (2021). Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study. Tropical Medicine and International Health, 26(3), 327-334. https://doi.org/10.1111/tmi.13524

Objective: This study tested the hypothesis that systemic inflammation is inversely associated with haemoglobin levels in adolescent girls in India. Methods: The study population consisted of adolescent girls aged between 10 and 19years living in a r... Read More about Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study.

Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India (2020)
Journal Article
Kulkarni, M. M., Kamath, V. G., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (2021). Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India. Tobacco Control, 30(5), 560-566. https://doi.org/10.1136/tobaccocontrol-2019-055353

Background Exposure to smoking in films is a recognised cause of smoking uptake among children. In India, in an attempt to protect children, films containing smoking are required to include tobacco control messaging including audiovisual disclaimers,... Read More about Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India.

Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study (2020)
Journal Article
Young, B., Fogarty, A. W., Skelly, R., Shaw, D., Thurley, P., Sturrock, N., …Cranwell, J. (2020). Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study. Public Health, 185, 338-340. https://doi.org/10.1016/j.puhe.2020.06.023

© 2020 The Authors Objectives: There is a need to improve efficiency in healthcare delivery without compromising quality of care. One approach is the development and evaluation of behavioural strategies to reduce unnecessary use of common tests. Howe... Read More about Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study.

Phenotypic and functional translation of IL33 genetics in asthma (2020)
Journal Article
Ketelaar, M. E., Portelli, M. A., Dijk, F. N., Shrine, N., Faiz, A., Vermeulen, C. J., …Nawijn, M. C. (2021). Phenotypic and functional translation of IL33 genetics in asthma. Journal of Allergy and Clinical Immunology, 147(1), 144-157. https://doi.org/10.1016/j.jaci.2020.04.051

© 2020 Background: Asthma is a complex disease with multiple phenotypes that may differ in disease pathobiology and treatment response. IL33 single nucleotide polymorphisms (SNPs) have been reproducibly associated with asthma. IL33 levels are elevate... Read More about Phenotypic and functional translation of IL33 genetics in asthma.

Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study (2020)
Journal Article
Young, B., Fogarty, A. W., Skelly, R., Shaw, D., Sturrock, N., Norwood, M., …Cranwell, J. (2020). Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study. BMC Medical Informatics and Decision Making, 20(1), 80. https://doi.org/10.1186/s12911-020-1087-2

BACKGROUND: Avoidable use of diagnostic tests can both harm patients and increase the cost of healthcare. Nudge-type educational interventions have potential to modify clinician behaviour while respecting clinical autonomy and responsibility, but the... Read More about Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study.

Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium (2020)
Journal Article
Portelli, M. A., Dijk, F. N., Ketelaar, M. E., Shrine, N., Hankinson, J., Bhaker, S., …Sayers, I. (2020). Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI insight, 5(8), Article 132446. https://doi.org/10.1172/jci.insight.132446

The IL1RL1 (ST2) gene locus is robustly associated with asthma; however, the contribution of single nucleotide polymorphisms (SNPs) in this locus to specific asthma subtypes and the functional mechanisms underlying these associations remain to be def... Read More about Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.

Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study (2020)
Journal Article
Suárez-Medina, R., Venero-Fernández, S., Alvarez-Valdés, V., Sardiñas-Baez, N., Cristina, C., Loinaz-Gonzalez, M., …Fogarty, A. W. (2020). Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study. BMJ Open, 10(4), Article e034192. https://doi.org/10.1136/bmjopen-2019-034192

Objectives: Asthma has not been extensively studied in low-income and middle-income countries, where risk factors and access to treatment may differ from more affluent countries. We aimed to identify the prevalence of asthma and local risk factors in... Read More about Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study.

The potential to quantify polypharmacy in older adult hospital inpatients using electronic prescribing software: A feasibility study (2020)
Journal Article
Connor, N., Woodward, S., Norwood, M., Sturrock, N., Woodward, J., Skelly, R., …Fogarty, A. (2020). The potential to quantify polypharmacy in older adult hospital inpatients using electronic prescribing software: A feasibility study. Health and Technology, 10, 823–826. https://doi.org/10.1007/s12553-020-00419-4

Polypharmacy in older adults is a growing problem, as some drugs may be either unnecessary or even harmful. Admission to hospital under a Medicine for the Elderly specialist physicians represents an opportunity to review patients’ medication. The rec... Read More about The potential to quantify polypharmacy in older adult hospital inpatients using electronic prescribing software: A feasibility study.

Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study (2019)
Journal Article
Ahankari, A. S., Tata, L. J., & Fogarty, A. W. (2020). Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study. Maternal and Child Nutrition, 16(2), https://doi.org/10.1111/mcn.12908

Objective: We aimed to explore the association of physical parameters with haemoglobin (Hb) levels to test the hypothesis that impaired physical development is associated with anaemia. Methods: A cross-sectional survey study recruited adolescent... Read More about Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study.

Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study (2019)
Journal Article
Young, B., Cranwell, J., Fogarty, A. W., Skelly, R., Sturrock, N., Norwood, M., …Thurley, P. (2019). Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study. BMC Health Services Research, 19, https://doi.org/10.1186/s12913-019-4712-y

Background: In the context of increasing availability of computed tomography (CT) scans, judicious use of ionising radiation is a priority to minimise the risk of future health problems. Hence, education of clinicians on the risks and benefits of CT... Read More about Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study.

Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis (2019)
Journal Article
Webb, K., Fogarty, A., Barrett, D. A., Nash, E. F., Whitehouse, J. L., Smyth, A. R., …Cámara, M. (2019). Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis. Journal of Medical Microbiology, 68(12), 1823-1828. https://doi.org/10.1099/jmm.0.001099

Introduction : Pseudomonas aeruginosa is an important respiratory pathogen in cystic fibrosis (CF), which is associated with an accelerated decline in lung function, frequent pulmonary exacerbations and increased mortality. P. aeruginosa produces in... Read More about Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.

Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study (2019)
Journal Article
Lewis, S., Young, B., Thurley, P., Shaw, D., Cranwell, J., Skelly, R., …Fogarty, A. W. (2019). Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study. Future Healthcare Journal, 6(3), 204-208. https://doi.org/10.7861/fhj.2019-0001

Background: Behavioural insights or ‘nudge’ theory suggests that non-directional interventions may be used to modify human behaviour. We have tested the hypothesis that the provision of the cost of common blood tests with their results may modify sub... Read More about Does cost feedback modify demand for common blood tests in secondary care? A prospective controlled intervention study.

Rojiroti microfinance and child nutrition: a cluster randomised trial (2019)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A., Allen, S., …Smyth, A. R. (2020). Rojiroti microfinance and child nutrition: a cluster randomised trial. Archives of Disease in Childhood, 105(3), 229-235. https://doi.org/10.1136/archdischild-2018-316471

Objective To determine whether Rojiroti microfinance, for poor Indian women, improves child nutrition. Design Cluster randomised trial. Setting Tolas (village communities) in Bihar State. Participants Women and children under 5 years. Int... Read More about Rojiroti microfinance and child nutrition: a cluster randomised trial.

Changes in Asthma Mortality in England and Wales since 2001 (2019)
Journal Article
Shaw, D. E., Gaynor, C. M., & Fogarty, A. (2019). Changes in Asthma Mortality in England and Wales since 2001. Thorax, 74(12), 1174-1175. https://doi.org/10.1136/thoraxjnl-2019-213350

The number of deaths from asthma in England and Wales has not changed significantly over the last decade. This lack of improvement has received attention from both national asthma guidelines and the media. We examined asthma death data from the Offic... Read More about Changes in Asthma Mortality in England and Wales since 2001.

Global differences in geography, religion and other societal factors are associated with sex differences in mortality from suicide: An ecological study of 182 countries (2019)
Journal Article
Alothman, D., & Fogarty, A. (2020). Global differences in geography, religion and other societal factors are associated with sex differences in mortality from suicide: An ecological study of 182 countries. Journal of Affective Disorders, 260, 67-72. https://doi.org/10.1016/j.jad.2019.08.093

© 2019 Background: Over 800,000 individuals die as a consequence of suicide annually, and almost two thirds of these deaths are in males. This analysis aimed to explore sex differences in global suicide rates with regards to geographic location, reli... Read More about Global differences in geography, religion and other societal factors are associated with sex differences in mortality from suicide: An ecological study of 182 countries.

Prevalence and risk factors for initiating alcohol and tobacco consumption in adolescents living in urban and rural Ethiopia (2019)
Journal Article
Getachew, S., Lewis, S., Britton, J., Deressa, W., & Fogarty, A. W. (2019). Prevalence and risk factors for initiating alcohol and tobacco consumption in adolescents living in urban and rural Ethiopia. Public Health, 174, 118-126. https://doi.org/10.1016/j.puhe.2019.05.029

© 2019 The Authors Objectives: African countries are potential high growth markets for the alcohol and tobacco industries. This study aimed to identify exposures that are associated with initiating use of alcohol and tobacco products in young people... Read More about Prevalence and risk factors for initiating alcohol and tobacco consumption in adolescents living in urban and rural Ethiopia.

What is the association between price and economic activity with cigarette consumption in Cuba from 1980 to 2014? (2019)
Journal Article
Varona-Perez*, P., Bridges, S., Lorenzo-Vazquez, E., Suarez-Medina, R., Venero-Fernandez, S., Langley, T., …Fogarty, A. W. (2019). What is the association between price and economic activity with cigarette consumption in Cuba from 1980 to 2014?. Public Health, 173, 126-129. https://doi.org/10.1016/j.puhe.2019.05.014

Objectives: Cuba is a tobacco producing country that has been economically isolated as a consequence of an embargo imposed by the USA, and has also experienced a severe economic depression in the 1990s after the withdrawal of support by the former So... Read More about What is the association between price and economic activity with cigarette consumption in Cuba from 1980 to 2014?.

Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study (2019)
Journal Article
Lewis, S., Shaw, D., Langley, T., Fogarty, A., Young, B., & Cranwell, O. (2019). Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study. Clinical Medicine, 19(4), 290-293. https://doi.org/10.7861/clinmedicine.19-4-290

Computerised tomography (CT) is readily available in developed countries. As one of the side-effects includes an increased risk of cancer, interventions that may encourage more judicious use of CT scans are important. Behavioural economics theory inc... Read More about Evaluation of a nudge intervention providing simple feedback to clinicians of the consequence of radiation exposure on demand for computerised tomography scans: a prospective, controlled study.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study (2018)
Journal Article
Shrine, N., Portelli, M. A., John, C., Soler Artigas, M., Bennett, N., Hall, R., …Sayers, I. (2019). Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. Lancet Respiratory Medicine, 7(1), 20-34. https://doi.org/10.1016/S2213-2600%2818%2930389-8

Background Few genetic studies that focus on moderate-to-severe asthma exist. We aimed to identity novel genetic variants associated with moderate-to-severe asthma, see whether previously identified genetic variants for all types of asthma contribut... Read More about Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

The association between dengue immunoglobulin G titres with previous clinical dengue infection and white cell counts in Cuban children: a population-based study (2018)
Journal Article
Suarez-Medina, R., Venero-Fernández, S. J., Batista-Gutierrez, L., de los Angeles Estrada-Rondon, Y., Alfonso-Hernandez, A., Casanave-Guarnaluce, D., …HINASIC (Historia Natural de la Sibilancia en Cuba/Natural History of Wheezing in Cuba) Study Group. (2018). The association between dengue immunoglobulin G titres with previous clinical dengue infection and white cell counts in Cuban children: a population-based study. PLoS ONE, 13(11), 1-9. https://doi.org/10.1371/journal.pone.0207391

Background The prevalence of dengue infection is increasing globally. There are few prospective population-based surveillance studies of the immunological and inflammatory consequences of exposure to dengue virus in young children. Objective To... Read More about The association between dengue immunoglobulin G titres with previous clinical dengue infection and white cell counts in Cuban children: a population-based study.

The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data (2018)
Journal Article
Rodríguez-Calá, F., Suárez-Medina, R., Josefina Venero-Fernández, S., Smyth, A., Carr, S. B., & Fogarty, A. W. (2019). The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data. Journal of Cystic Fibrosis, 18(4), 522-524. https://doi.org/10.1016/j.jcf.2018.10.007

Background: We aimed to establish a national cystic fibrosis (CF) registry for Cuba, a developing country. Methods: Regional centres that deliver care for all CF patients provided information for a national database. Findings: The prevalence of CF... Read More about The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data.

An evaluation of a price transparency intervention for two commonly prescribed medications on total institutional expenditure: a prospective study (2018)
Journal Article
Langley, T., Lacey, J., Johnson, A., Newman, C., Khare, M., Skelly, R., …Fogarty, A. W. (2018). An evaluation of a price transparency intervention for two commonly prescribed medications on total institutional expenditure: a prospective study. Future Hospital Journal, 5(3), 198-202. https://doi.org/10.7861/futurehosp.5-3-198

Importance: Providing cost feedback has been demonstrated to decrease demand from clinicians. Objective: We tested the hypothesis that providing the cost of drugs to clinicians would modify total expenditure. Design: A prospective study design with... Read More about An evaluation of a price transparency intervention for two commonly prescribed medications on total institutional expenditure: a prospective study.

Epilepsy mortality trends in Cuba compared with England and Wales: 1987–2010 (2018)
Journal Article
Suárez-Medina, R., Morales-Chacón, L. M., Venero-Fernández, S. J., Liu, C., Fogarty, A. W., & Neligan, A. (2018). Epilepsy mortality trends in Cuba compared with England and Wales: 1987–2010. Epilepsy and Behavior, 85, https://doi.org/10.1016/j.yebeh.2018.04.031

There are limited epilepsy mortality data from developing countries and Latin America in particular. We examined national epilepsy mortality data from Cuba and contrasted them with comparable data from England and Wales. National epilepsy mortality d... Read More about Epilepsy mortality trends in Cuba compared with England and Wales: 1987–2010.

Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study (2017)
Journal Article
Lewis, S., Langley, T., Lacey, J., Skelly, R., Norwood, M., Sturrock, N., & Fogarty, A. W. (2017). Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study. Clinical Medicine, 17(6), https://doi.org/10.7861/clinmedicine.17-6-504

We hypothesised that delays in providing non-urgent medication step-downs at weekends to medical management may be associated with increased length of stay.In a novel use of electronic prescribing data, we analysed emergency admissions from a busy ac... Read More about Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study.

Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015 (2017)
Journal Article
Thurley, P., Crookdake, J., Norwood, M., Sturrock, N., & Fogarty, A. W. (in press). Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015. British Journal of Radiology, https://doi.org/10.1259/bjr.20170467

OBJECTIVE: Avoiding unnecessary radiation exposure is a clinical priority in children and young adults. We aimed to explore demand for CT scans in a busy general hospital with particular interest in the period of transition from paediatric to adult m... Read More about Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015.

Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis (2017)
Journal Article
Hurley, M., Fogarty, A. W., McKeever, T. M., Goss, C., Rosenfeld, M., & Smyth, A. R. (in press). Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis. Annals of the American Thoracic Society, https://doi.org/10.1513/AnnalsATS.201705-376OC

Rationale: Consensus is lacking regarding anti-staphylococcal antibiotic prophylaxis use for young children with cystic fibrosis. Prophylaxis is recommended in the UK, but recommended against in the US. Objectives: To test the hypothesis that anti-... Read More about Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis.

Association between infection with H. pylori and atopy in young Ethiopian children: a longitudinal study (2017)
Journal Article
Taye, B., Enquselassie, F., Tsegaye, A., Amberbir, A., Medhin, G., Fogarty, A. W., …Davey, G. (in press). Association between infection with H. pylori and atopy in young Ethiopian children: a longitudinal study. Clinical and Experimental Allergy, 47(10), https://doi.org/10.1111/cea.12995

Background: Epidemiological evidence from developed countries indicates that Helicobacter pylori infection correlates with a reduced risk of atopy and allergic disorders, however limited data are available from low-income countries. Objective: We... Read More about Association between infection with H. pylori and atopy in young Ethiopian children: a longitudinal study.

Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis (2017)
Journal Article
Barr, H. L., Cámara, M., Barrett, D., Williams, P., Forrester, D., Smyth, A., …Fogarty, A. W. (in press). Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis. ERJ Open Research, 3(3), https://doi.org/10.1183/23120541.00057-2017

Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study (2017)
Journal Article
Ahankari, A. S., Myles, P. R., Dixit, J., Tata, L. J., & Fogarty, A. W. (2017). Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study. Public Health, 151, 63-73. https://doi.org/10.1016/j.puhe.2017.06.023

Objective: The aim of this prospective study was to estimate the prevalence and risk factors for maternal anaemia and low birth weight in pregnant women living in Maharashtra state, India. Study design: Prospective study Methods: Women between 3... Read More about Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study.

Prevalence and associated risk factors of malaria among adults in East Shewa Zone of Oromia Regional State, Ethiopia: a cross-sectional study (2017)
Journal Article
Tadesse, F., Fogarty, A. W., & Deressa, W. (2018). Prevalence and associated risk factors of malaria among adults in East Shewa Zone of Oromia Regional State, Ethiopia: a cross-sectional study. BMC Public Health, 18(1), Article 25. https://doi.org/10.1186/s12889-017-4577-0

BACKGROUND: Malaria is one of the most important causes of morbidity and mortality in sub-Saharan Africa. The disease is prevalent in over 75% of the country's area making it the leading public health problems in the country. Information on the preva... Read More about Prevalence and associated risk factors of malaria among adults in East Shewa Zone of Oromia Regional State, Ethiopia: a cross-sectional study.

Household air pollution and lung function in Indian adults: a cross-sectional study (2017)
Journal Article
Dave, M., Ahankari, A. S., Myles, P. R., Arokiasamy, P., Uttamacharya, Khobragade, P., …Fogarty, A. W. (2017). Household air pollution and lung function in Indian adults: a cross-sectional study. International Journal of Tuberculosis and Lung Disease, 21(6), https://doi.org/10.5588/ijtld.16.0615

Exposure to air pollution produced by cooking is common in developing countries, and represents a potentially avoidable cause of lung disease. Cross-sectional data were collected by the World Health Organization's Study on Global AGEing and Adult Hea... Read More about Household air pollution and lung function in Indian adults: a cross-sectional study.

A metabolomic analytical approach permits identification of urinary biomarkers for Plasmodium falciparum infection: a case–control study (2017)
Journal Article
Abdelrazig, S. M., Ortori, C. A., Davey, G., Deressa, W., Mulleta, D., Barrett, D. A., …Fogarty, A. W. (2017). A metabolomic analytical approach permits identification of urinary biomarkers for Plasmodium falciparum infection: a case–control study. Malaria Journal, 16, Article 229. https://doi.org/10.1186/s12936-017-1875-z

BACKGROUND: Currently available diagnostic techniques of Plasmodium falciparum infection are not optimal for non-invasive, population-based screening for malaria. It was hypothesized that a mass spectrometry-based metabolomics approach could identify... Read More about A metabolomic analytical approach permits identification of urinary biomarkers for Plasmodium falciparum infection: a case–control study.

Factors associated with preterm delivery and low birth weight: a study from rural Maharashtra, India (2017)
Journal Article
Ahankari, A., Bapat, S., Myles, P., Fogarty, A., & Tata, L. (in press). Factors associated with preterm delivery and low birth weight: a study from rural Maharashtra, India. F1000Research, 6(72), https://doi.org/10.12688/f1000research.10659.1

Background: Although preterm delivery and low birth weight (LBW) have been studied in India, findings may not be generalisable to rural areas such as the Marathwada region of Maharashtra state. There is limited information available on maternal and c... Read More about Factors associated with preterm delivery and low birth weight: a study from rural Maharashtra, India.

Healthcare benefits linked with Below Poverty Line registration in India: Observations from Maharashtra Anaemia Study (MAS) (2017)
Journal Article
Ahankari, A., Fogarty, A., Tata, L., & Myles, P. R. (2017). Healthcare benefits linked with Below Poverty Line registration in India: Observations from Maharashtra Anaemia Study (MAS). F1000Research, 6(25), https://doi.org/10.12688/f1000research.10556.1

A 2015 Lancet paper by Patel et al. on healthcare access in India comprehensively discussed national health programmes where some benefits are linked with the country’s Below Poverty Line (BPL) registration scheme. BPL registration aims to support po... Read More about Healthcare benefits linked with Below Poverty Line registration in India: Observations from Maharashtra Anaemia Study (MAS).

sTREM-1 is elevated in cystic fibrosis and correlates with proteases (2017)
Journal Article
Forrester, D., Barr, H. L., Fogarty, A., & Knox, A. (2017). sTREM-1 is elevated in cystic fibrosis and correlates with proteases. Pediatric Pulmonology, 52(4), 467-471. https://doi.org/10.1002/ppul.23650

Background: sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases... Read More about sTREM-1 is elevated in cystic fibrosis and correlates with proteases.

The association of low birth weight with serum C reactive protein in three year old children living in Cuba: a population-based prospective study (2016)
Journal Article
Venero-Fernández, S. J., Fundora-Hernández, H., Batista-Gutierrez, L., Suárez-Medina, R., de la C. Mora-Faife, E., del Valle-Infante, I., …Fogarty, A. W. (in press). The association of low birth weight with serum C reactive protein in three year old children living in Cuba: a population-based prospective study. American Journal of Human Biology, https://doi.org/10.1002/ajhb.22936

Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease (2016)
Journal Article
Skelly, R., Brown, L., & Fogarty, A. W. (2017). Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease. Parkinsonism and Related Disorders, 35, https://doi.org/10.1016/j.parkreldis.2016.11.004

Background: Punctual delivery of dopaminergic medication to Parkinson's disease (PD) patients may be important in optimizing disease control. We tested the hypothesis that prompt delivery of l-dopa medications to emergency hospital inpatients was ass... Read More about Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study (2016)
Journal Article
Barr, H. L., Halliday, N., Barrett, D. A., Williams, P., Forrester, D. L., Peckham, D., …Fogarty, A. W. (2017). Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16(2), 230-238. https://doi.org/10.1016/j.jcf.2016.10.005

Background Pulmonary P. aeruginosa infection is associated with poor outcomes in cystic fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to expectorate sputum. Specific P. aeruginosa 2-alkyl-4-quinolones are det... Read More about Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study.

Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India (2016)
Journal Article
Ahankari, A. S., Dixit, J., Fogarty, A. W., Tata, L. J., & Myles, P. R. (2016). Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India. BMJ Innovations, 2, https://doi.org/10.1136/bmjinnov-2016-000139

Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting. Methods: Participants included girls aged between 13... Read More about Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India.

Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008 (2016)
Journal Article
Hutchinson, J. P., McKeever, T. M., Fogarty, A. W., Navaratnam, V., & Hubbard, R. B. (in press). Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008. European Respiratory Journal, 48, https://doi.org/10.1183/13993003.00378-2016

Introduction: International guidelines and new targeted therapies for idiopathic pulmonary fibrosis have increased the need for accurate diagnosis of interstitial lung disease, which may lead to more surgical lung biopsies. This study aims to assess... Read More about Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008.

Prevalence of iron deficiency anaemia and risk factors in 1,010 adolescent girls from rural Maharashtra, India: a cross-sectional survey (2016)
Journal Article
Ahankari, A. S., Myles, P. R., Fogarty, A. W., Dixit, J., & Tata, L. J. (2017). Prevalence of iron deficiency anaemia and risk factors in 1,010 adolescent girls from rural Maharashtra, India: a cross-sectional survey. Public Health, 142, https://doi.org/10.1016/j.puhe.2016.07.010

Objective: Iron deficiency anaemia (IDA) is the most common nutritional disorder observed in adolescent girls in India. Our aim was to investigate the prevalence and risk factors associated with IDA in rural Maharashtra, India to address current evid... Read More about Prevalence of iron deficiency anaemia and risk factors in 1,010 adolescent girls from rural Maharashtra, India: a cross-sectional survey.

Effect of Helicobacter pylori infection on growth trajectories in young Ethiopian children: a longitudinal study (2016)
Journal Article
Taye, B., Enquselassie, F., Tsegaye, A., Amberbir, A., Medhin, G., Fogarty, A., …Davey, G. (2016). Effect of Helicobacter pylori infection on growth trajectories in young Ethiopian children: a longitudinal study. International Journal of Infectious Diseases, 50, 57-66. https://doi.org/10.1016/j.ijid.2016.08.005

Background Helicobacter pylori infection has been associated with early childhood growth impairment in high- and middle-income countries; however, few studies have examined this relationship within low-income countries or have used a longitudinal de... Read More about Effect of Helicobacter pylori infection on growth trajectories in young Ethiopian children: a longitudinal study.

Population-based weight loss and gain do not explain trends in asthma mortality in Cuba: a prospective study from 1964 to 2014 (2016)
Journal Article
Suárez-Medina, R., Venero-Fernández, S. J., Britton, J., & Fogarty, A. W. (2016). Population-based weight loss and gain do not explain trends in asthma mortality in Cuba: a prospective study from 1964 to 2014. Respiratory Medicine, 118, https://doi.org/10.1016/j.rmed.2016.07.003

Background The increase in prevalence of obesity is a possible risk factor for asthma in developed countries. As the people of Cuba experienced an acute population-based decrease in weight in the 1990s, we tested the hypothesis that national weigh... Read More about Population-based weight loss and gain do not explain trends in asthma mortality in Cuba: a prospective study from 1964 to 2014.

Assessment of a non-invasive haemoglobin sensor NBM 200 among pregnant women in rural India (2016)
Journal Article
Ahankari, A. S., Fogarty, A. W., Tata, L. J., Dixit, J., & Myles, P. R. (in press). Assessment of a non-invasive haemoglobin sensor NBM 200 among pregnant women in rural India. BMJ Innovations, 2, https://doi.org/10.1136/bmjinnov-2015-000085

Objective: This study aimed to assess a non-invasive haemoglobin sensor NBM 200 in pregnant women in a rural Indian setting. Methods: The study population consisted of women between 3 to 5 months of pregnancy, from 33 villages in Tuljapur and Lohara... Read More about Assessment of a non-invasive haemoglobin sensor NBM 200 among pregnant women in rural India.

Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis (2015)
Journal Article
Forrester, D. L., Knox, A. J., Smyth, A. R., Barr, H. L., Simms, R., Pacey, S. J., …Fogarty, A. W. (2016). Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis. Pediatric Pulmonology, 51(3), 253-257. https://doi.org/10.1002/ppul.23370

Rationale: Pulmonary infection and malnutrition in cystic fibrosis are associated with decreased survival. Glutamine has a possible anti-microbial effect, with a specific impact against Pseudomonas aeruginosa. We aimed to test the hypothesis that ora... Read More about Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial: Oral Glutamine Supplementation in Cystic Fibrosis.

In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000-2011 (2015)
Journal Article
Hutchinson, J. P., Fogarty, A. W., McKeever, T. M., & Hubbard, R. B. (2016). In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000-2011. American Journal of Respiratory and Critical Care Medicine, 193(10), 1161-1167. https://doi.org/10.1164/rccm.201508-1632OC

Rationale: Surgical lung biopsy can help to determine a specific diagnosis in interstitial lung disease, but has associated risks. Most currently available mortality data are derived from case series and may not be generalizable to broader population... Read More about In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000-2011.

Effect of early and current Helicobacter pylori infection on the risk of anaemia in 6.5-year-old Ethiopian children (2015)
Journal Article
Taye, B., Enquselassie, F., Tsegaye, A., Amberbir, A., Medhin, G., Fogarty, A. W., …Davey, G. (2015). Effect of early and current Helicobacter pylori infection on the risk of anaemia in 6.5-year-old Ethiopian children. BMC Infectious Diseases, 15(1), Article 270. https://doi.org/10.1186/s12879-015-1012-y

Background Epidemiological and clinical studies in high income countries have suggested that Helicobacter pylori (H. pylori) may cause anaemia, but evidence is lacking from low income countries.We examined associations between H. pylori infection... Read More about Effect of early and current Helicobacter pylori infection on the risk of anaemia in 6.5-year-old Ethiopian children.

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients (2015)
Journal Article
Ravipati, S., Baldwin, D. R., Barr, H. L., Fogarty, A. W., & Barrett, D. A. (in press). Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients. Metabolomics, 11(6), https://doi.org/10.1007/s11306-015-0811-x

There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype. A prospective study design was used with a study population of patients with suspected lung... Read More about Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients.

Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review (2015)
Journal Article
Hutchinson, J. P., Fogarty, A. W., Hubbard, R. B., & McKeever, T. M. (2015). Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review. European Respiratory Journal, 46(3), https://doi.org/10.1183/09031936.00185114

Introduction: As idiopathic pulmonary fibrosis emerges as an important public health problem, there is a need to coordinate data on incidence and mortality globally. This study aims to systematically assess all available studies to investigate the gl... Read More about Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review.

Complications and mortality in hereditary hemorrhagic telangiectasia: a population-based study (2015)
Journal Article
Donaldson, J., McKeever, T. M., Hall, I. P., Hubbard, R., & Fogarty, A. W. (2015). Complications and mortality in hereditary hemorrhagic telangiectasia: a population-based study. Neurology, 84(18), https://doi.org/10.1212/WNL.0000000000001538

OBJECTIVES: Studies report that the risks of significant neurologic complications (including stroke, cerebral abscess, and migraine) and hemorrhagic sequelae are high in patients with hereditary hemorrhagic telangiectasia (HHT), and that life expe... Read More about Complications and mortality in hereditary hemorrhagic telangiectasia: a population-based study.

Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-?-treated macrophages to pseudomonas aeruginosa infection (2015)
Journal Article
Singh, S., Barr, H. L., Liu, Y., Robins, A., Heeb, S., Williams, P., …Martinez-Pomares, L. (2015). Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-γ-treated macrophages to pseudomonas aeruginosa infection. PLoS ONE, 10(2), Article e0117447. https://doi.org/10.1371/journal.pone.0117447

Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe infections at compromised epithelial surfaces, such those found in burns, wounds, and in lungs damaged by mechanical ventilation or recurrent infections, particularly in cystic... Read More about Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-?-treated macrophages to pseudomonas aeruginosa infection.

Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India (2015)
Journal Article
Ahankari, A. S., & Fogarty, A. W. (2015). Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India. International journal of medical science and public health, 4(1), https://doi.org/10.5455/ijmsph.2015.1109201428

Background: The existence of female feticide in India is well known. However, limited data are available on the association of socioeconomic status (SES) on sex ratio at live birth in disadvantaged populations, despite the fact that 33% of the popula... Read More about Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India.

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection (2015)
Journal Article
Darch, S. E., McNally, A., Harrison, F., Corander, J., Barr, H. L., Paszkiewicz, K., …Diggle, S. P. (2015). Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection. Scientific Reports, 5, Article 7649. https://doi.org/10.1038/srep07649

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant to multiple antibiotics. Here, we investigate the phenotypic and genotyp... Read More about Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection.

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis (2015)
Journal Article
Barr, H. L., Halliday, N., Cámara, M., Barrett, D. A., Williams, P., Forrester, D. L., …Fogarty, A. W. (2015). Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis. European Respiratory Journal, 46(4), 1046-1054. https://doi.org/10.1183/09031936.00225214

Copyright © ERS 2015. Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for... Read More about Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis.

What have studies of non-industrialized countries told us about the cause of allergic disease? (2014)
Journal Article
Fogarty, A. W. (in press). What have studies of non-industrialized countries told us about the cause of allergic disease?. Clinical and Experimental Allergy, 45(1), https://doi.org/10.1111/cea.12339

The increase in allergic diseases that was observed in countries that had experienced rapid economic growth since the mid-20th century initiated a search for environmental exposures that may explain these phenomena that continues to the present day.... Read More about What have studies of non-industrialized countries told us about the cause of allergic disease?.

Increasing global mortality from idiopathic pulmonary fibrosis in the twenty-first century (2014)
Journal Article
Hutchinson, J. P., McKeever, T. M., Fogarty, A. W., Navaratnam, V., & Hubbard, R. B. (2014). Increasing global mortality from idiopathic pulmonary fibrosis in the twenty-first century. Annals of the American Thoracic Society, 11(8), https://doi.org/10.1513/AnnalsATS.201404-145OC

Rationale: Recent evidence from the United Kingdom suggests that the number of deaths from idiopathic pulmonary fibrosis is increasing, although comparable international data are limited. Objectives: We aimed to collate death certification data f... Read More about Increasing global mortality from idiopathic pulmonary fibrosis in the twenty-first century.

Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial (2014)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A. W., Allen, S., …Smyth, A. R. (2014). Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial. Trials, 15, Article 298. https://doi.org/10.1186/1745-6215-15-298

Background: The United Nations Millennium Development Goals include targets for the health of children under five years old. Poor health is linked to poverty and microfinance initiatives are economic interventions that may improve health by breaking... Read More about Feasibility and pilot study of the effects of microfinance on mortality and nutrition in children under five amongst the very poor in India: study protocol for a cluster randomized controlled trial.

Exposure to Helicobacter pylori infection in early childhood and the risk of allergic disease and atopic sensitization: a longitudinal birth cohort study (2014)
Journal Article
Amberbir, A., Medhin, G., Abegaz, W., Hanlon, C., Robinson, K., Fogarty, A. W., …Davey, G. (2014). Exposure to Helicobacter pylori infection in early childhood and the risk of allergic disease and atopic sensitization: a longitudinal birth cohort study. Clinical and Experimental Allergy, 44(4), https://doi.org/10.1111/cea.12289

Background: An inverse relation between Helicobacter pylori infection and allergic disease has been reported by a range of independent epidemiological studies, but evidence from longitudinal studies is scarce. Objective: We have investigated the... Read More about Exposure to Helicobacter pylori infection in early childhood and the risk of allergic disease and atopic sensitization: a longitudinal birth cohort study.

Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study (2014)
Journal Article
Hurley, M., McKeever, T. M., Prayle, A. P., Smyth, A. R., & Fogarty, A. W. (2014). Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study. Journal of Cystic Fibrosis, 13(4), https://doi.org/10.1016/j.jcf.2013.12.002

Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. Method: Death registration data analysis (US, England & Wa... Read More about Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study.

Risk factors for wheezing in infants born in Cuba (2013)
Journal Article
Venero-Fernandez, S., Suarez-Medina, R., Mora-Faife, E., Garcia-Garcia, G., Valle-Infante, I., Gomez-Marrero, L., …Fogarty, A. W. (2013). Risk factors for wheezing in infants born in Cuba. QJM: An International Journal of Medicine, 106(11), https://doi.org/10.1093/qjmed/hct143

Background: Cuba is a unique country, and despite limited economic development, has an excellent health system. However, the prevalence of asthma symptoms in children in Havana, Cuba, is unusually high. Aim: As early life exposures are critical t... Read More about Risk factors for wheezing in infants born in Cuba.

The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study (2013)
Journal Article
Donaldson, J. W., McKeever, T. M., Hall, I. P., Hubbard, R., & Fogarty, A. W. (2014). The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study. Thorax, 69(2), 161-167. https://doi.org/10.1136/thoraxjnl-2013-203720

Background Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder of aberrant blood vessel development characterised by arteriovenous malformations. HHT is associated with significant morbidity due to complications inc... Read More about The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study.

Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case–control study (2013)
Journal Article
Navaratnam, V., Fogarty, A. W., McKeever, T. M., Thompson, N., Jenkins, G., Johnson, S. R., …Hubbard, R. B. (2014). Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case–control study. Thorax, 69(3), 207-215. https://doi.org/10.1136/thoraxjnl-2013-203740

BACKGROUND: Laboratory studies suggest that the clotting cascade is activated in fibrotic lungs. Since humans vary in their tendency to clot due to a variety of inherited or acquired defects, we investigated whether a prothrombotic state increases th... Read More about Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case–control study.

The acute impact of a hematopoietic allograft on lung function and inflammation: a prospective observational study (2013)
Journal Article
Enocson, A., Hubbard, R., McKeever, T. M., Russell, N., Byrne, J., Das-Gupta, E., …Fogarty, A. W. (2013). The acute impact of a hematopoietic allograft on lung function and inflammation: a prospective observational study. BMC Pulmonary Medicine, 13(Januar), Article 6. https://doi.org/10.1186/1471-2466-13-2

Background: No studies have investigated the immediate impact of receiving an allogeneic hematopoietic stem cell transplant (HSCT) on pulmonary inflammation or lung function. Methods: Using a prospective study design, we quantified the changes in... Read More about The acute impact of a hematopoietic allograft on lung function and inflammation: a prospective observational study.

Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis
Other
Hurley, M., Smyth, A. R., Fogarty, A. W., McKeever, T. M., Rosenfeld, M., & Goss, C. (2016). Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis