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The impact of the ‘hub and spoke’ model of care for lung cancer and equitable access to surgery (2014)
Journal Article
Khakwani, A., Rich, A. L., Powell, H. A., Tata, L. J., Stanley, R. A., Baldwin, D. R., …Hubbard, R. B. (2014). The impact of the ‘hub and spoke’ model of care for lung cancer and equitable access to surgery. Thorax, 70(2), https://doi.org/10.1136/thoraxjnl-2014-205841

Objectives: To determine the influence of where a patient is first seen (either surgical or non-surgical centre) and patient features on having surgery for non-small cell lung cancer (NSCLC). Design: Cross-sectional study from individual patients... Read More about The impact of the ‘hub and spoke’ model of care for lung cancer and equitable access to surgery.

Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data (2014)
Journal Article
Dhalwani, N. N., Szatkowski, L., Coleman, T., Fiaschi, L., & Tata, L. J. (2014). Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data. British Journal of General Practice, Article e554-e560. https://doi.org/10.3399/bjgp14X681361

Background Licensing arrangements for nicotine replacement therapy (NRT) in the UK were broadened in 2005 to allow prescribing to pregnant smokers. However, estimates of NRT prescribing in pregnant females in the UK are currently lacking. Aim To... Read More about Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data.

Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England (2014)
Journal Article
Abdul Sultan, A., Grainge, M. J., West, J., Fleming, K. M., Nelson-Piercy, C., & Tata, L. J. (in press). Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England. Blood, 124(18), https://doi.org/10.1182/blood-2014-05-572834

For women with preeclampsia, BMI >30 kg/m2, infection, or those having cesarean delivery, VTE risk remained elevated for 6 weeks postpartum.For women with postpartum hemorrhage or preterm birth, the relative rate of VTE was only increased for the... Read More about Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England.

Women with celiac disease present with fertility problems no more often than women in the general population (2014)
Journal Article
Dhalwani, N. N., West, J., Sultan, A. A., Ban, L., & Tata, L. J. (in press). Women with celiac disease present with fertility problems no more often than women in the general population. Gastroenterology, 147(6), Article 1267-1274.e1. https://doi.org/10.1053/j.gastro.2014.08.025

BACKGROUND & AIMS: Studies have associated infertility with celiac disease. However, these included small numbers of women attending infertility specialist services and subsequently screened for celiac disease, and therefore may not have been represe... Read More about Women with celiac disease present with fertility problems no more often than women in the general population.

Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England (2014)
Journal Article
Abdul Sultan, A., Tata, L. J., Fleming, K. M., Crooks, C. J., Ludvigsson, J. F., Dhalwani, N. N., …West, J. (in press). Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England. American Journal of Gastroenterology, 109(10), https://doi.org/10.1038/ajg.2014.196

OBJECTIVES: Evidence-based information about adverse birth outcomes and pregnancy complications is crucial when counseling women with celiac disease (CD); however, limited population-based data on such risks exist. We estimated these for pregnant wom... Read More about Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England.

First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study (2014)
Journal Article
Ban, L., West, J., Gibson, J. E., Fiaschi, L., Sokal, R., Doyle, P., …Tata, L. J. (2014). First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS ONE, 9(6), Article e100996. https://doi.org/10.1371/journal.pone.0100996

BACKGROUND: Despite their widespread use the effects of taking benzodiazepines and non-benzodiazepine hypnotics during pregnancy on the risk of major congenital anomaly (MCA) are uncertain. The objectives were to estimate absolute and relative risks... Read More about First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.

Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study (2014)
Journal Article
West, J., Fleming, K. M., Tata, L. J., Card, T. R., & Crooks, C. J. (2014). Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study. American Journal of Gastroenterology, 109(5), 757-768. https://doi.org/10.1038/ajg.2014.55

OBJECTIVES: Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes... Read More about Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.

Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study (2014)
Journal Article
Ban, L., Gibson, J. E., West, J., Fiaschi, L., Sokal, R., Smeeth, L., …Tata, L. J. (in press). Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 121(12), https://doi.org/10.1111/1471-0528.12682

OBJECTIVE: To estimate risks of major congenital anomaly (MCA) among children of mothers prescribed antidepressants during early pregnancy or diagnosed with depression but without antidepressant prescriptions. DESIGN: Population-based cohort study.... Read More about Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.

Small-Cell Lung Cancer in England: Trends in Survival and Chemotherapy Using the National Lung Cancer Audit (2014)
Journal Article
Khakwani, A., Rich, A. L., Tata, L. J., Powell, H. A., Stanley, R. A., Baldwin, D. R., & Hubbard, R. B. (2014). Small-Cell Lung Cancer in England: Trends in Survival and Chemotherapy Using the National Lung Cancer Audit. PLoS ONE, 9(2), Article e89426. https://doi.org/10.1371/journal.pone.0089426

Background The purpose of this study was to identify trends in survival and chemotherapy use for individuals with small-cell lung cancer (SCLC) in England using the National Lung Cancer Audit (NLCA). Methods We used data from the NLCA database... Read More about Small-Cell Lung Cancer in England: Trends in Survival and Chemotherapy Using the National Lung Cancer Audit.

Smoking cessation advice recorded during pregnancy in United Kingdom primary care (2014)
Journal Article
Hardy, B., Szatkowski, L., Tata, L. J., Coleman, T., & Dhalwani, N. (2014). Smoking cessation advice recorded during pregnancy in United Kingdom primary care. BMC Family Practice, 15(21), https://doi.org/10.1186/1471-2296-15-21

Background: United Kingdom (UK) national guidelines recommend that all pregnant women who smoke should be advised to quit at every available opportunity, and brief cessation advice is an efficient and cost-effective means to increase quit rates. The... Read More about Smoking cessation advice recorded during pregnancy in United Kingdom primary care.

How to read a cohort study (2014)
Book Chapter
Tata, L. J. (2014). How to read a cohort study. In N. J. Talley, G. Richard Locke III, P. Moayyedi, J. West, & Y. A. Saito (Eds.), GI Epidemiology: Diseases and Clinical Methodology (15-29). (Second). John Wiley & Sons, Ltd. https://doi.org/10.1002/9781118727072.ch2

The cohort is the basis of all epidemiologic study designs as it is the closest way to study the natural progression of people's life course over which the temporal relationship between exposures and outcomes can be assessed. Although a cohort is def... Read More about How to read a cohort study.

Treatment decisions and survival for people with small-cell lung cancer (2014)
Journal Article
Powell, H., Tata, L., Baldwin, D., Potter, V., Stanley, R., Khakwani, A., & Hubbard, R. (in press). Treatment decisions and survival for people with small-cell lung cancer. British Journal of Cancer, 110(4), https://doi.org/10.1038/bjc.2013.812

Background: Chemotherapy improves survival for many patients with SCLC, and hence it is important to understand variations in practice and outcomes for this treatment strategy. Methods: We used the National Lung Cancer Audit and Hospital Episodes... Read More about Treatment decisions and survival for people with small-cell lung cancer.

The direct medical costs of epilepsy in children and young people: a population-based study of health resource utilisation (2014)
Journal Article
Ali, M. A. S., Elliott, R. A., & Tata, L. J. (in press). The direct medical costs of epilepsy in children and young people: a population-based study of health resource utilisation. Epilepsy Research, 108(3), https://doi.org/10.1016/j.eplepsyres.2013.12.014

We described the health resource utilisation (HRU) and associated direct medical costs of managing epilepsy in children and young people (CYP) using population-level data from the United Kingdom. The study cohort were CYP born between 1988 and 20... Read More about The direct medical costs of epilepsy in children and young people: a population-based study of health resource utilisation.

Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England (2013)
Journal Article
Sultan, A. A., West, J., Tata, L. J., Fleming, K. M., Nelson-Piercy, C., & Grainge, M. J. (2013). Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England. BMJ, 347(7935), Article 11. https://doi.org/10.1136/bmj.f6099

Objective: To examine the potential for preventing venous thromboembolism during and after antepartum hospital admissions in pregnant women. Design: Cohort study using linked primary (Clinical Practice Research Datalink) and secondary (Hospital E... Read More about Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.

Risk factors for scald injury in children under 5 years of age: a case–control study using routinely collected data (2013)
Journal Article
Shah, M., Orton, E., Tata, L., Gomes, C., & Kendrick, D. (2013). Risk factors for scald injury in children under 5 years of age: a case–control study using routinely collected data. Burns, 39(7), https://doi.org/10.1016/j.burns.2013.03.022

Scald injury is common, accounting for half of all burns in pre-school children. Most scalds are preventable and health professionals can play an important role in targeting interventions to those at greatest risk. However, the potential for routinel... Read More about Risk factors for scald injury in children under 5 years of age: a case–control study using routinely collected data.

Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications (2013)
Journal Article
Ban, L., Tata, L. J., Fiaschi, L., & Card, T. R. (2014). Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications. Gastroenterology, 146(1), https://doi.org/10.1053/j.gastro.2013.09.061

Background & aims: Concerns persist about the risk of major congenital anomalies in children of women with inflammatory bowel disease (IBD), and whether medication use affects risk. We assessed these risks, and variations in use of medications by wom... Read More about Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications.

Completeness of maternal smoking status recording during pregnancy in United Kingdom primary care data (2013)
Journal Article
Dhalwani, N. N., Tata, L. J., Coleman, T., Fleming, K. M., & Szatkowski, L. (2013). Completeness of maternal smoking status recording during pregnancy in United Kingdom primary care data. PLoS ONE, 8(9), Article e72218. https://doi.org/10.1371/journal.pone.0072218

Background: Given the health impacts of smoking during pregnancy and the opportunity for primary healthcare teams to encourage pregnant smokers to quit, we assessed the completeness of gestational smoking status recording in primary care data and inv... Read More about Completeness of maternal smoking status recording during pregnancy in United Kingdom primary care data.

The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis (2013)
Journal Article
Sultan, A. A., Tata, L. J., Grainge, M. J., & West, J. (2013). The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis. PLoS ONE, 8(7), Article e70310. https://doi.org/10.1371/journal.pone.0070310

Background: Recent linkage between primary and secondary care data has provided valuable information for studying heath outcomes that may initially present in different health care settings. The aim of this study was therefore, twofold: to use linke... Read More about The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis.