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Effect of maternal dietary restriction during pregnancy on lamb carcass characteristics and muscle fiber composition (2007)
Journal Article
Daniel, Z. C., Brameld, J. M., Craigon, J., Scollan, N. D., & Buttery, P. J. (2007). Effect of maternal dietary restriction during pregnancy on lamb carcass characteristics and muscle fiber composition. Journal of Animal Science, 85(6), 1565-1576. https://doi.org/10.2527/jas.2006-743

Two experiments were conducted to determine whether the decreased proportion of fast muscle fibers seen previously in 2-wk-old lambs from ewes that were dietary restricted from d 30 to 70 of gestation are still evident in older lambs and what the con... Read More about Effect of maternal dietary restriction during pregnancy on lamb carcass characteristics and muscle fiber composition.

Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters (2007)
Journal Article
Schuhler, S., Warner, A., Finney, N., Bennett, G. W., Ebling, F. J., & Brameld, J. M. (2007). Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters. Journal of Neuroendocrinology, 19(4), 239-249. https://doi.org/10.1111/j.1365-2826.2006.01524.x

Thyrotrophin-releasing hormone (TRH) is known to play an important role in the control of food intake and energy metabolism in addition to its actions on the pituitary-thyroid axis. We have previously shown that central administration of TRH decrease... Read More about Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters.

Effects of fatty acids on skeletal muscle cell differentiation in vitro (2006)
Journal Article
Hurley, M. S., Flux, C., Salter, A. M., & Brameld, J. M. (2006). Effects of fatty acids on skeletal muscle cell differentiation in vitro. British Journal of Nutrition, 95(3), 623-630. https://doi.org/10.1079/BJN20051711

Previous studies have shown stimulatory effects of linoleic acid (LA, C18:2) on differentiation of rat muscle cells in culture (Allen et al. 1985), but there appears to be little investigation of the effects of other fatty acids. The present study th... Read More about Effects of fatty acids on skeletal muscle cell differentiation in vitro.

The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb (2005)
Journal Article
Fahey, A. J., Brameld, J. M., Parr, T., & Buttery, P. J. (2005). The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb. Journal of Animal Science, 83(11), 2564-2571. https://doi.org/10.2527/2005.83112564x

There is a need to improve the lean tissue content of ruminant animals destined for meat production. Muscle fiber number is set during fetal development. The effect of undernutrition of pregnant ewes on subsequent muscle fiber characteristics of thei... Read More about The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb.

The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb (2005)
Journal Article
Fahey, A. J., Brameld, J. M., Parr, T., & Buttery, P. J. (2005). The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb. Journal of Animal Science, 83(11), 2564-2571. https://doi.org/10.2527/2005.83112564x

There is a need to improve the lean tissue content of ruminant animals destined for meat production. Muscle fiber number is set during fetal development. The effect of undernutrition of pregnant ewes on subsequent muscle fiber characteristics of thei... Read More about The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb.

Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus (2005)
Journal Article
Fahey, A. J., Brameld, J. M., Parr, T., & Buttery, P. J. (2005). Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus. Journal of Animal Science, 83(10), 2330-2338. https://doi.org/10.2527/2005.83102330x

The number of muscle fibers within a muscle has been found to be of high importance for the growth potential of an animal, and this number is set during fetal development. The objective of this study was to identify the ontogeny of muscle cell differ... Read More about Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus.

Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus (2005)
Journal Article
Fahey, A. J., Brameld, J. M., Parr, T., & Buttery, P. J. (2005). Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus. Journal of Animal Science, 83(10), 2330-2338

The number of muscle fibers within a muscle has been found to be of high importance for the growth potential of an animal, and this number is set during fetal development. The objective of this study was to identify the ontogeny of muscle cell differ... Read More about Ontogeny of factors associated with proliferation and differentiation of muscle in the ovine fetus.

Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters (2004)
Journal Article
Parr, T., Jewell, K. K., Sensky, P. L., Brameld, J. M., Bardsley, R. G., & Buttery, P. J. (2004). Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters. Archives of Biochemistry and Biophysics, 427(1), 8-15. https://doi.org/10.1016/j.abb.2004.04.001

Calpastatin is the specific endogenous inhibitor of calpain proteinase that is encoded by a single gene. Transient transfection assays in both a non-fusing skeletal muscle and non-muscle cell-line demonstrated that the putative porcine calpastatin pr... Read More about Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters.

Nutritional and hormonal control of muscle growth and fat deposition (2003)
Journal Article
Brameld, J. M., Fahey, A. J., Langley-Evans, S. C., & Buttery, P. J. (2003). Nutritional and hormonal control of muscle growth and fat deposition. Archives Animal Breeding, 46(5 SUPPL.), 143-156

This review will consider the processes of skeletal muscle (myogenesis) and fat (adipogenesis) development and the factors involved in regulating them in a variety of species. In particular, the effects of hormones and maternal nutrition during diffe... Read More about Nutritional and hormonal control of muscle growth and fat deposition.

Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle (2000)
Journal Article
Brameld, J. M., Mostyn, A., Dandrea, J., Stephenson, T. J., Dawson, J. M., Buttery, P. J., & Symonds, M. E. (2000). Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle. Journal of Endocrinology, 167(3), 429-437. https://doi.org/10.1677/joe.0.1670429

We investigated the influence of maternal dietary restriction between days 28 and 80 of gestation followed by re-feeding to the intake of well-fed ewes up to 140 days of gestation (term is 147 days) in sheep, on expression of mRNA for insulin-like gr... Read More about Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle.

Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep (2000)
Journal Article
Heasman, L., Brameld, J., Mostyn, A., Budge, H., Dawson, J., Buttery, P., …Symonds, M. E. (2000). Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep. Reproduction, Fertility and Development, 12(7-8), 345-350. https://doi.org/10.1071/RD00115

The present study was designed to determine whether altered placental size, as a consequence of maternal nutrient restriction in sheep between 28 and 77 days gestation, is associated with a modified relationship between fetal weight or dimensions and... Read More about Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep.

Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep (2000)
Journal Article
Heasman, L., Brameld, J., Mostyn, A., Budge, H., Dawson, J., Buttery, P., …Symonds, M. E. (2000). Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep. Reproduction, Fertility and Development, 12(7-8), 345-350. https://doi.org/10.1071/rd00115

The present study was designed to determine whether altered placental size, as a consequence of maternal nutrient restriction in sheep between 28 and 77 days gestation, is associated with a modified relationship between fetal weight or dimensions and... Read More about Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep.

Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes (1999)
Journal Article
Brameld, J. M., Gilmour, R. S., & Buttery, P. J. (1999). Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes. Journal of Nutrition, 129(7), 1298-1306. https://doi.org/10.1093/jn/129.7.1298

Nutrients and hormones are major determinants of animal growth, but the mechanisms of how nutrients influence the growth process are still unclear. A primary pig hepatocyte culture system was used to investigate possible direct effects of glucose and... Read More about Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes.

Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes (1999)
Journal Article
Brameld, J. M., Gilmour, R. S., & Buttery, P. J. (1999). Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes. Journal of Nutrition, 129(7), 1298-1306. https://doi.org/10.1093/jn/129.7.1298

Nutrients and hormones are major determinants of animal growth, but the mechanisms of how nutrients influence the growth process are still unclear. A primary pig hepatocyte culture system was used to investigate possible direct effects of glucose and... Read More about Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes.

Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue (1996)
Journal Article
Brameld, J. M., Atkinson, J. L., Saunders, J. C., Pell, J. M., Buttery, P. J., & Gilmour, R. S. (1996). Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue. Journal of Animal Science, 74(8), 1832-1841. https://doi.org/10.2527/1996.7481832x

The effects of growth hormone (GH) and dietary protein on expression of IGF-I and GH receptor (GHR) genes in liver, muscle, and fat of pigs were investigated. Forty-eight intact male Large White x Landrace pigs were allotted to eight treatment groups... Read More about Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue.

Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig (1996)
Journal Article
Brameld, J. M., Atkinson, J. L., Budd, T. J., Saunders, J. C., Pell, J. M., Salter, A. M., …Buttery, P. J. (1996). Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig. Animal Science, 62(3), 555-559. https://doi.org/10.1017/S1357729800015101

The work described was carried out to study the expression of insulin-like growth factor 1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue from three breeds of pig with varying growth characteristics. The t... Read More about Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig.

Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle (1995)
Journal Article
Brameld, J. M., Weller, P. A., Pell, J. M., Buttery, P. J., & Gilmour, R. S. (1995). Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle. Animal Science, 61(2), 333-339. https://doi.org/10.1017/S1357729800013886

The growth hormone-insulin-like growth factor (GH-IGF) axis is involved in the control of postnatal growth in all animals studied to date. At birth, blood levels of IGF-1 are low, although levels of GH are high. Thus a switching occurs during the pos... Read More about Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle.