All Outputs (90)

Novel bioresorbable textile composites for medical applications (2018)
Conference Proceeding
Zhu, C., Ahmed, I., Parsons, A. J., Wang, Y., Tan, C., Liu, J., …Liu, X. (2018). Novel bioresorbable textile composites for medical applications. In N/A

Currently, phosphate glass fibre (PGF) reinforced composites are a potential solution for bone repairing due to sufficient mechanical properties and full bioresorbability. In this study, a small inkle-type loom for hand weaving facilitated the produc... Read More about Novel bioresorbable textile composites for medical applications.

Effects of Fe2O3 addition and annealing on the mechanical and dissolution properties of MgO- and CaO-containing phosphate glass fibres for bio-applications (2018)
Journal Article
Tan, C., Ahmed, I., Parsons, A. J., Zhu, C., Betanzos, F. B., & Liu, X. (2018). Effects of Fe2O3 addition and annealing on the mechanical and dissolution properties of MgO- and CaO-containing phosphate glass fibres for bio-applications. Biomedical Glasses, 4(1), https://doi.org/10.1515/bglass-2018-0006

This paper investigated the preparation of phosphate glass fibres (PGFs) in the following systems: i) 45P2O5-5B2O3-5Na2O-(29-x)CaO-16MgO-(x)Fe2O3and ii) 45P2O5-5B2O3-5Na2O-24CaO-(21-x)MgO-(x)Fe2O3(where x = 5, 8 and 11 mol%) for biomedical applicatio... Read More about Effects of Fe2O3 addition and annealing on the mechanical and dissolution properties of MgO- and CaO-containing phosphate glass fibres for bio-applications.

Flexible and transparent films produced from cellulose nanowhisker reinforced agarose (2018)
Journal Article
Felfel, R. M., Hossain, K. M. Z., Kabir, S. F., Yee, S. L., Ahmed, I., & Grant, D. M. (2018). Flexible and transparent films produced from cellulose nanowhisker reinforced agarose. Carbohydrate Polymers, 194, https://doi.org/10.1016/j.carbpol.2018.04.005

Transparent and flexible nanocomposite films with a range of Agarose to Cellulose Nano-Whisker (CNW) ratios were produced using never-dried CNWs. The incorporation of never-dried CNWs within Agarose played an important role in the surface roughness (... Read More about Flexible and transparent films produced from cellulose nanowhisker reinforced agarose.

Porous calcium phosphate glass microspheres for orthobiologic applications (2018)
Journal Article
Hossain, K. M. Z., Patel, U., Kennedy, A. R., Macri-Pellizzeri, L., Sottile, V., Grant, D. M., …Ahmed, I. (2018). Porous calcium phosphate glass microspheres for orthobiologic applications. Acta Biomaterialia, 72, 396-406. https://doi.org/10.1016/j.actbio.2018.03.040

© 2018 Orthobiologics is a rapidly advancing field utilising cell-based therapies and biomaterials to enable the body to repair and regenerate musculoskeletal tissues. This paper reports on a cost-effective flame spheroidisation process for producti... Read More about Porous calcium phosphate glass microspheres for orthobiologic applications.

Electric field-assisted orientation of short phosphate glass fibers on stainless steel for biomedical applications (2018)
Journal Article
Chen, Q., Jing, J., Qi, H., Ahmed, I., Yang, H., Liu, X., …Boccaccini, A. R. (2018). Electric field-assisted orientation of short phosphate glass fibers on stainless steel for biomedical applications. ACS Applied Materials and Interfaces, 10(14), 11529-11538. https://doi.org/10.1021/acsami.8b01378

Structural and compositional modifications of metallic implant surfaces are being actively investigated to achieve improved bone-to-implant bonding. In this study, a strategy to modify bulk metallic surfaces by electrophoretic deposition (EPD) of sho... Read More about Electric field-assisted orientation of short phosphate glass fibers on stainless steel for biomedical applications.

Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride (2018)
Journal Article
Macri-Pellizzeri, L., De Melo, N., Ahmed, I., Grant, D. M., Scammell, B., & Sottile, V. (2018). Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride. Tissue Engineering Part C Methods, 24(3), https://doi.org/10.1089/ten.TEC.2017.0400

The final stage of in vitro osteogenic differentiation is characterized by the production of mineral deposits containing calcium cations and inorganic phosphates, which populate the extracellular matrix surrounding the cell monolayer. Conventional hi... Read More about Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride.

Simulating damage onset and evolution in fully bio-resorbable composite under three-point bending (2018)
Journal Article
Gao, X., Chen, M., Yang, X., Harper, L., Ahmed, I., & Lu, J. (2018). Simulating damage onset and evolution in fully bio-resorbable composite under three-point bending. Journal of the Mechanical Behavior of Biomedical Materials, 81, https://doi.org/10.1016/j.jmbbm.2018.02.022

This paper presents a strain-based damage model to predict the stress-strain relationship and investigate the damage onset and evolution of the fibre and matrix of a fully bio-resorbable phosphate glass fibre reinforced composite under three-point be... Read More about Simulating damage onset and evolution in fully bio-resorbable composite under three-point bending.

Single solvent based film casting method for the production of porous polymer films (2018)
Journal Article
Hossain, K. M. Z., Felfel, R. M., Ogbilikana, P. S., Thakker, D., Grant, D. M., Scotchford, C., & Ahmed, I. (2018). Single solvent based film casting method for the production of porous polymer films. Macromolecular Materials and Engineering, 303, https://doi.org/10.1002/mame.201700628

A single solvent based film casting process for fabricating porous polymer films was developed in this study. The porous film was produced by mixing concentrated polylactic acid/ chloroform solution (20 wt%) and fresh chloroform solvent followed by f... Read More about Single solvent based film casting method for the production of porous polymer films.

Role of geometrical cues in bone marrow-derived mesenchymal stem cell survival, growth and osteogenic differentiation (2017)
Journal Article
Gupta, D., Grant, D. M., Hossain, K. M. Z., Ahmed, I., & Sottile, V. (2018). Role of geometrical cues in bone marrow-derived mesenchymal stem cell survival, growth and osteogenic differentiation. Journal of Biomaterials Applications, 32(7), https://doi.org/10.1177/0885328217745699

Mesenchymal stem cells play a vital role in bone formation process by differentiating into osteoblasts, in a tissue that offers not a flat but a discontinuous three-dimensional (3D) topography in vivo. In order to understand how geometry may be affec... Read More about Role of geometrical cues in bone marrow-derived mesenchymal stem cell survival, growth and osteogenic differentiation.

Novel bioresorbable phosphate glass fiber textile composites for medical applications (2017)
Journal Article
Zhu, C., Ahmed, I., Parsons, A. J., Wang, Y., Tan, C., Liu, J., …Liu, X. (2018). Novel bioresorbable phosphate glass fiber textile composites for medical applications. Polymer Composites, 39(S1), E140-E151. https://doi.org/10.1002/pc.24499

A manual bench-top inkle-type loom was designed to enable hand woven textiles. These PGF textiles, along with unidirectional (UD) fiber mats made from the same batch of yarns, were utilized to manufacture fully resorbable textile composites (T-C), un... Read More about Novel bioresorbable phosphate glass fiber textile composites for medical applications.

Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking (2017)
Journal Article
Chen, M., Lu, J., Felfel, R. M., Parsons, A. J., Irvine, D. J., Rudd, C. D., & Ahmed, I. (2017). Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking. Composites Science and Technology, 150, 1-15. https://doi.org/10.1016/j.compscitech.2017.07.006

Fully bioresorbable phosphate based glass fibre reinforced polycaprolactone (PCL/PGF) composites are potentially excellent candidates to address current issues experienced with use of metal implants for hard tissue repair, such as stress shielding ef... Read More about Wet and dry flexural high cycle fatigue behaviour of fully bioresorbable glass fibre composites: In-situ polymerisation versus laminate stacking.

Structural and physico-chemical analysis of calcium/ strontium substituted, near-invert phosphate based glasses for biomedical applications (2017)
Journal Article
Patel, U., Moss, R., Hossain, K., Kennedy, A., Barney, E., Ahmed, I., & Hannon, A. (2017). Structural and physico-chemical analysis of calcium/ strontium substituted, near-invert phosphate based glasses for biomedical applications. Acta Biomaterialia, 60, 109-127. https://doi.org/10.1016/j.actbio.2017.07.002

Neutron diffraction, 23Na and 31P NMR and FTIR spectroscopy have been used to investigate the structural effects of substituting CaO with SrO in a 40P2O5·(16 x)CaO·20Na2O·24MgO·xSrO glass, where x is 0, 4, 8, 12 and 16 mol%. The 31P solid-state NMR r... Read More about Structural and physico-chemical analysis of calcium/ strontium substituted, near-invert phosphate based glasses for biomedical applications.

Mechanical, structural and dissolution properties of heat treated thin-film phosphate based glasses (2017)
Journal Article
Stuart, B. W., Gimeno-Fabra, M., Segal, J., Ahmed, I., & Grant, D. M. (2017). Mechanical, structural and dissolution properties of heat treated thin-film phosphate based glasses. Applied Surface Science, 416, 605-617. https://doi.org/10.1016/j.apsusc.2017.04.110

Here we show the deposition of 2.7 μm thick phosphate based glass films produced by magnetron sputtering, followed by post heat treatments at 500 °C. Variations in degradation properties pre and post heat treatment were attributed to the formation of... Read More about Mechanical, structural and dissolution properties of heat treated thin-film phosphate based glasses.

Structural, thermal and dissolution properties of MgO- and CaO-containing borophosphate glasses: effect of Fe2O3 addition (2017)
Journal Article
Tan, C., Ahmed, I., Parsons, A. J., Sharmin, N., Zhu, C., Liu, J., …Liu, X. (2017). Structural, thermal and dissolution properties of MgO- and CaO-containing borophosphate glasses: effect of Fe2O3 addition. Journal of Materials Science, 52(12), 7489-7502. https://doi.org/10.1007/s10853-017-0981-1

This paper investigated manufacture of high-durability phosphate glass fibres for biomedical applications. Five different borophosphate glass formulations in the systems of 45P2O5–5B2O3–5Na2O–(29 − x)CaO–16MgO–(x)Fe2O3 and 45P2O5–5B2O3–5Na2O–24CaO–(2... Read More about Structural, thermal and dissolution properties of MgO- and CaO-containing borophosphate glasses: effect of Fe2O3 addition.

Compositional dependency on dissolution rate and cytocompatibility of phosphate-based glasses: effect of B2O3 and Fe2O3 addition (2017)
Journal Article
Sharmin, N., Gu, F., Ahmed, I., & Parsons, A. J. (2017). Compositional dependency on dissolution rate and cytocompatibility of phosphate-based glasses: effect of B2O3 and Fe2O3 addition. Journal of Tissue Engineering, 8, 204173141774445. https://doi.org/10.1177/2041731417744454

The unique property of phosphate-based glasses and fibres to be completely dissolved in aqueous media is largely dependent on the glass composition. This article focuses on investigating the effect of replacing Na2O with 3 and 5 mol% Fe2O3 on cytocom... Read More about Compositional dependency on dissolution rate and cytocompatibility of phosphate-based glasses: effect of B2O3 and Fe2O3 addition.

Structure–properties relationships in fibre drawing of bioactive phosphate glasses (2017)
Journal Article
Muñoz-Senovilla, L., Muñoz, F., Tricot, G., Ahmed, I., & Parsons, A. J. (2017). Structure–properties relationships in fibre drawing of bioactive phosphate glasses. Journal of Materials Science, 52(15), 9166-9178. https://doi.org/10.1007/s10853-017-0773-7

New bioactive phosphate glasses suitable for continuous fibre production are investigated in this work. The structure of both bulk and fibres from Na2O–CaO–MgO–P2O5 glasses has been studied by means of Raman and 31P and 23Na nuclear magnetic resonanc... Read More about Structure–properties relationships in fibre drawing of bioactive phosphate glasses.

Phosphate Glass Fibres and Their Composites (2016)
Book Chapter
Hossain, K. M. Z., Felfel, R. M., Grant, D. M., & Ahmed, I. (2016). Phosphate Glass Fibres and Their Composites. In A. R. Boccaccini, D. S. Brauer, & L. Hupa (Eds.), Bioactive Glasses: Fundamentals, Technology and Applications (257-285). Royal Society of Chemistry. https://doi.org/10.1039/9781782622017-00257

An overview of the research conducted utilising phosphate glass fibres (PGFs), their manufacturing processes and utilisation potential for biomedical applications is presented in this chapter. Phosphate glasses of varying compositions in the form of... Read More about Phosphate Glass Fibres and Their Composites.

Structural, thermal, in vitro degradation and cytocompatibility properties of P2O5-B2O3-CaO-MgO-Na2O-Fe2O3 glasses (2016)
Journal Article
Zhu, C., Ahmed, I., Parsons, A., Hossain, K. M. Z., Rudd, C. D., Liu, J., & Liu, X. (2017). Structural, thermal, in vitro degradation and cytocompatibility properties of P2O5-B2O3-CaO-MgO-Na2O-Fe2O3 glasses. Journal of Non-Crystalline Solids, 457, https://doi.org/10.1016/j.jnoncrysol.2016.11.001

Borophosphate glasses with compositions of (48 ? x)P2O5-(12 + x)B2O3-14CaO-20MgO-1Na2O-5Fe2O3 (where x = 0, 3, 8 mol%) were prepared via a melt-quenching process. The effects of replacing P2O5 with B2O3 on the structural, thermal, degradation propert... Read More about Structural, thermal, in vitro degradation and cytocompatibility properties of P2O5-B2O3-CaO-MgO-Na2O-Fe2O3 glasses.

Structure, viscosity and fibre drawing properties of phosphate-based glasses: effect of boron and iron oxide addition (2016)
Journal Article
Sharmin, N., Rudd, C. D., Parsons, A. J., & Ahmed, I. (2016). Structure, viscosity and fibre drawing properties of phosphate-based glasses: effect of boron and iron oxide addition. Journal of Materials Science, 51(16), 7523-7535. https://doi.org/10.1007/s10853-016-0032-3

© 2016, Springer Science+Business Media New York. Resorbable phosphate-based glasses have been applied as fibrous reinforcement for resorbable polymers for fracture fixation. The mechanical properties of these composites largely depend on the mechani... Read More about Structure, viscosity and fibre drawing properties of phosphate-based glasses: effect of boron and iron oxide addition.

Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites (2016)
Journal Article
Barrera Betanzos, F., Gimeno-Fabra, M., Segal, J., Grant, D., & Ahmed, I. (2016). Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites. Materials and Design, 100, https://doi.org/10.1016/j.matdes.2016.03.108

The use of thermoplastic composites based on poly(lactic) acid and phosphate glass fibres over metallic alloys for clinical restorative treatment is highly beneficial due to their biocompatibility and biodegradability. However, difficulties in achiev... Read More about Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites.