All Outputs (90)

Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial (2020)
Journal Article
Gunn, D., Murthy, R., Major, G., Wilkinson-Smith, V., Hoad, C., Marciani, L., …Spiller, R. (2020). Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial. American Journal of Clinical Nutrition, 112(3), 595–602. https://doi.org/10.1093/ajcn/nqaa173

Background Wheat bran, nopal, and psyllium are examples of particulate, viscous and particulate, and viscous fibers, respectively, with laxative properties yet contrasting fermentability. Objectives We assessed the fermentability of these fi... Read More about Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial.

Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial (2020)
Journal Article
Tanasescu, R., Tench, C. R., Constantinescu, C. S., Telford, G., Singh, S., Frakich, N., …Pritchard, D. I. (2020). Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial. JAMA Neurology, 77(9), 1089-1098. https://doi.org/10.1001/jamaneurol.2020.1118

© 2020 American Medical Association. All rights reserved. Importance: Studies suggest gut worms induce immune responses that can protect against multiple sclerosis (MS). To our knowledge, there are no controlled treatment trials with helminth in MS.... Read More about Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial.

Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors (2020)
Journal Article
Zhang, Z., Robinson, L., Jia, T., Quinlan, E. B., Tay, N., Chu, C., …Desrivières, S. (2021). Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors. Biological Psychiatry, 90(12), 853-862. https://doi.org/10.1016/j.biopsych.2020.06.003

BACKGROUND: Eating disorders are common in adolescence, devastating and strongly comorbid with other psychiatric disorders. Yet, little is known about their etiology to develop effective preventive measures. METHODS: Longitudinal assessments of... Read More about Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors.

Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system (2020)
Journal Article
Hill, R. M., Boto, E., Rea, M., Holmes, N., Leggett, J., Coles, L. A., …Brookes, M. J. (2020). Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system. NeuroImage, 219, Article 116995. https://doi.org/10.1016/j.neuroimage.2020.116995

© 2020 The Authors Magnetoencephalography (MEG) is a powerful technique for functional neuroimaging, offering a non-invasive window on brain electrophysiology. MEG systems have traditionally been based on cryogenic sensors which detect the small extr... Read More about Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system.

The haemodynamics of the human placenta in utero (2020)
Journal Article
Dellschaft, N. S., Hutchinson, G., Shah, S., Jones, N. W., Bradley, C., Leach, L., …Gowland, P. A. (2020). The haemodynamics of the human placenta in utero. PLoS Biology, 18(5), Article e3000676. https://doi.org/10.1371/journal.pbio.3000676

© 2020 Dellschaft et al. We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are cons... Read More about The haemodynamics of the human placenta in utero.

Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket (2020)
Journal Article
Maity, A., Singh, B., Sharma, K., Paul, S., Madhu, P. K., & Polshettiwar, V. (2020). Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket. ACS Materials Letters, 2(7), 699-704. https://doi.org/10.1021/acsmaterialslett.9b00527

© 2020 American Chemical Society. The use of metal-organic frameworks (MOFs) in the field of catalysis is growing exponentially due to their high surface area and distinctive active sites. In this work, we report a novel understanding of the active s... Read More about Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket.

Pandemic preparedness of community pharmacies for COVID-19 (2020)
Journal Article
Bahlol, M., & Dewey, R. S. (2021). Pandemic preparedness of community pharmacies for COVID-19. Research in Social and Administrative Pharmacy, 17(1), 1888-1896. https://doi.org/10.1016/j.sapharm.2020.05.009

© 2020 Elsevier Inc. Background: Community pharmacies provide an important healthcare service, which is broadly established, and constitutes the preferred and initial contact for members of the community. The significant value of community pharmacies... Read More about Pandemic preparedness of community pharmacies for COVID-19.

A probabilistic atlas of finger dominance in the primary somatosensory cortex (2020)
Journal Article
O’Neill, G., Sengupta, A., Asghar, M., Barratt, E., Besle, J., Schluppeck, D., …Sanchez Panchuelo, R. (2020). A probabilistic atlas of finger dominance in the primary somatosensory cortex. NeuroImage, 217, Article 116880. https://doi.org/10.1016/j.neuroimage.2020.116880

With the advent of ultra-high field (7T), high spatial resolution functional MRI (fMRI) has allowed the differentiation of the cortical representations of each of the digits at an individual-subject level in human primary somatosensory cortex (S1). H... Read More about A probabilistic atlas of finger dominance in the primary somatosensory cortex.

Improved fibre dispersion estimation using b-tensor encoding (2020)
Journal Article
Cottaar, M., Szczepankiewicz, F., Bastiani, M., Hernandez-Fernandez, M., Sotiropoulos, S. N., Nilsson, M., & Jbabdi, S. (2020). Improved fibre dispersion estimation using b-tensor encoding. NeuroImage, 215, https://doi.org/10.1016/j.neuroimage.2020.116832

© 2020 The Authors Measuring fibre dispersion in white matter with diffusion magnetic resonance imaging (MRI) is limited by an inherent degeneracy between fibre dispersion and microscopic diffusion anisotropy (i.e., the diffusion anisotropy expected... Read More about Improved fibre dispersion estimation using b-tensor encoding.

Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing (2020)
Journal Article
Autio, J. A., Glasser, M. F., Ose, T., Donahue, C. J., Bastiani, M., Ohno, M., …Hayashi, T. (2020). Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing. NeuroImage, 215, Article 116800. https://doi.org/10.1016/j.neuroimage.2020.116800

© 2020 The Author(s) Macaque monkeys are an important animal model where invasive investigations can lead to a better understanding of the cortical organization of primates including humans. However, the tools and methods for noninvasive image acquis... Read More about Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing.

Metal-based imaging agents: progress towards interrogating neurodegenerative disease (2020)
Journal Article
Sedgwick, A. C., Brewster, J. T., Harvey, P., Iovan, D. A., Smith, G., He, X., …James, T. D. (2020). Metal-based imaging agents: progress towards interrogating neurodegenerative disease. Chemical Society Reviews, 2020(10), 2886-2915. https://doi.org/10.1039/c8cs00986d

Central nervous system (CNS) neurodegeneration is defined by a complex series of pathological processes that ultimately lead to death. The precise etiology of these disorders remains unknown. Recent efforts show that a mechanistic understanding of th... Read More about Metal-based imaging agents: progress towards interrogating neurodegenerative disease.

Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy (2020)
Journal Article
Khalaf, A., Hoad, C. L., Blackshaw, E., Alyami, J., Spiller, R. C., Gowland, P. A., …Marciani, L. (2020). Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy. Diagnostics, 10(3), Article 170. https://doi.org/10.3390/diagnostics10030170

Measurement of gastric emptying is of clinical value for a range of conditions. Gamma scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) has recently increased. Previous comparison studies between MRI and GS sh... Read More about Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy.

Cortical thickness and formal thought disorder in schizophrenia: An ultra high-field network-based morphometry study (2020)
Journal Article
Palaniyappan, L., Al-Radaideh, A., Gowland, P. A., & Liddle, P. F. (2020). Cortical thickness and formal thought disorder in schizophrenia: An ultra high-field network-based morphometry study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 101, https://doi.org/10.1016/j.pnpbp.2020.109911

Background Persistent formal thought disorder (FTD) is a core feature of schizophrenia. Recent cognitive and neuroimaging studies indicate a distinct mechanistic pathway underlying the persistent positive FTD (pFTD or disorganized thinking), thoug... Read More about Cortical thickness and formal thought disorder in schizophrenia: An ultra high-field network-based morphometry study.

Batch-Mode Clinical-Scale Optical Hyperpolarization of Xenon-129 Using an Aluminum Jacket with Rapid Temperature Ramping (2020)
Journal Article
Chekmenev, E. Y., Birchall, J. R., Barlow, M. J., Nikolaou, P., Irwin, R. K., Coffey, A. M., …Molway, M. (2020). Batch-Mode Clinical-Scale Optical Hyperpolarization of Xenon-129 Using an Aluminum Jacket with Rapid Temperature Ramping. Analytical Chemistry, 92(6), 4309-4316. https://doi.org/10.1021/acs.analchem.9b05051

We present spin-exchange optical pumping (SEOP) using a third-generation (GEN-3) automated batch-mode clinical-scale 129Xe hyperpolarizer utilizing continuous high-power (∼170 W) pump laser irradiation and a novel aluminum jacket design for rapid tem... Read More about Batch-Mode Clinical-Scale Optical Hyperpolarization of Xenon-129 Using an Aluminum Jacket with Rapid Temperature Ramping.

Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study (2020)
Journal Article
Jung, J., Bungert, A., Bowtell, R., & Jackson, S. (2020). Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study. Frontiers in Human Neuroscience, 14, https://doi.org/10.3389/fnhum.2020.00031

Stimulating the primary motor cortex (M1) using transcranial magnetic stimulation (TMS) causes unique multisensory experience such as the targeted muscle activity, afferent/reafferent sensory feedback, tactile sensation over the scalp and “click” sou... Read More about Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study.

The role of node dynamics in shaping emergent functional connectivity patterns in the brain (2020)
Journal Article
Forrester, M., Crofts, J. J., Sotiropoulos, S., Coombes, S., & O’Dea, R. (2020). The role of node dynamics in shaping emergent functional connectivity patterns in the brain. Network Neuroscience, 4(2), 467-483. https://doi.org/10.1162/netn_a_00130

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure–function issue, treating a system of Jansen–Rit neural-mass nodes with... Read More about The role of node dynamics in shaping emergent functional connectivity patterns in the brain.

Measurement of brain lactate during visual stimulation using a long TE semi?LASER sequence at 7 T (2020)
Journal Article
Fernandes, C. C., Lanz, B., Chen, C., & Morris, P. G. (2020). Measurement of brain lactate during visual stimulation using a long TE semi?LASER sequence at 7 T. NMR in Biomedicine, 33(4), https://doi.org/10.1002/nbm.4223

Estimation of metabolic changes during neuronal activation represents a challenge for in vivo MRS, especially for metabolites with low concentration and signal overlap, such as lactate. In this work, we aimed to evaluate the feasibility of detecting... Read More about Measurement of brain lactate during visual stimulation using a long TE semi?LASER sequence at 7 T.

Human hippocampal CA3 damage disrupts both recent and remote episodic memories (2020)
Journal Article
Miller, T. D., Chong, T. T., Aimola Davies, A. M., Johnson, M. R., Irani, S. R., Husain, M., …Rosenthal, C. R. (2020). Human hippocampal CA3 damage disrupts both recent and remote episodic memories. eLife, 2020(9), Article 41836. https://doi.org/10.7554/elife.41836

Neocortical-hippocampal interactions support new episodic (event) memories, but there is conflicting evidence about the dependence of remote episodic memories on the hippocampus. In line with systems consolidation and computational theories of episod... Read More about Human hippocampal CA3 damage disrupts both recent and remote episodic memories.

Across?vendor standardization of semi?LASER for single?voxel MRS at 3T (2019)
Journal Article
Kantarci, K., Deelchand, D. K., Berrington, A., Noeske, R., Joers, J. M., Arani, A., …Öz, G. (2021). Across‐vendor standardization of semi‐LASER for single‐voxel MRS at 3T. NMR in Biomedicine, 34(5), Article e4218. https://doi.org/10.1002/nbm.4218

The semi‐adiabatic localization by adiabatic selective refocusing (sLASER) sequence provides single‐shot full intensity signal with clean localization and minimal chemical shift displacement error and was recommended by the international MRS Consensu... Read More about Across?vendor standardization of semi?LASER for single?voxel MRS at 3T.

Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo (2019)
Journal Article
Marciani, L., Lopez-Sanchez, P., Pettersson, S., Hoad, C., Abrehart, N., Ahnoff, M., & Strömf, A. (2019). Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo. Food and Function, 10(12), 7892-7899. https://doi.org/10.1039/C9FO01617A

The addition of gelling polysaccharides to sport-drinks may provide improved tolerability of drinks with high concentration of digestible carbohydrates (CHO), otherwise known to increase the risk of gastro-intestinal complaints among athletes under p... Read More about Alginate and HM-pectin in sports-drink give rise to intra-gastric gelation in-vivo.