Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
(2018)
Journal Article
Jevnikar, Z., Östling, J., Ax, E., Calvén, J., Thörn, K., Israelsson, E., …Olsson, H. K. (in press). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of Allergy and Clinical Immunology, https://doi.org/10.1016/j.jaci.2018.05.026
Background: Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) with asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthma is unclear. Objective: To explore the association... Read More about Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.