All Outputs (131)

Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit (2022)
Journal Article
Coleston-Shields, D. M., Challis, D., Worden, A., Broome, E., Dening, T., Guo, B., …Orrell, M. (2022). Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit. Trials, 23, Article 54. https://doi.org/10.1186/s13063-021-05995-y

Background: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people with dementia which arise... Read More about Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit.

The experience of apathy in dementia: A qualitative study (2021)
Journal Article
Baber, W., Chang, C. Y. M., Yates, J., & Dening, T. (2021). The experience of apathy in dementia: A qualitative study. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 17(57), Article e051411. https://doi.org/10.1002/alz.051411

Background The presence of apathy is associated with less favourable outcomes in dementia, including more rapid functional and cognitive decline, greater disease severity and increased mortality. We aimed to explore and gain an understanding into ho... Read More about The experience of apathy in dementia: A qualitative study.

The struggle of apathy in dementia (2021)
Journal Article
Dening, T., Baber, W., Chang, M., & Yates, J. (2022). The struggle of apathy in dementia. Aging and Mental Health, 26(10), 1909-1911. https://doi.org/10.1080/13607863.2021.2008309

Most people will recognise a sense of apathy within them, at some point during their lives, and this may present to a greater or lesser extent depending on the individual and the context. When people are asked about what apathy is, what it means, or... Read More about The struggle of apathy in dementia.

Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature (2021)
Journal Article
Di Lorito, C., Bosco, A., Peel, E., Hinchliff, S., Dening, T., Calasanti, T., …Harwood, R. H. (2022). Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature. Aging and Mental Health, 26(10), 1912-1921. https://doi.org/10.1080/13607863.2021.2008870

Objectives. More than 60% of people with dementia live at home, where assistance is usually provided by informal caregivers. Research on the experiences of the Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers is limited. This scoping review o... Read More about Are dementia services and support organisations meeting the needs of Lesbian, Gay, Bisexual and Transgender (LGBT) caregivers of LGBT people living with dementia? A scoping review of the literature.

Use of menopausal hormone therapy and risk of dementia: Nested case-control studies using QResearch and CPRD databases (2021)
Journal Article
Vinogradova, Y., Dening, T., Hippisley-Cox, J., Taylor, L., Moore, M., & Coupland, C. (2021). Use of menopausal hormone therapy and risk of dementia: Nested case-control studies using QResearch and CPRD databases. BMJ, 374, Article n2182. https://doi.org/10.1136/bmj.n2182

Objective To assess the risks of developing dementia associated with different types and durations of menopausal hormone therapy. Design Two nested case-control studies. Setting UK general practices contributing to QResearch or the Clinical Practice... Read More about Use of menopausal hormone therapy and risk of dementia: Nested case-control studies using QResearch and CPRD databases.

Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study (2021)
Journal Article
Casado-Espada, N. M., Alvarez-Navares, A., Lozano-Lopez, M. T., Gamonal-Limcaoco, R. S., de la Iglesia-Larrad, J., Garzón, M. Á., …Roncero, C. (2021). Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study. Heroin Addiction And Related Clinical Problems, 23(3), 37-44

Background: Increasing opioid consumption in recent years has given rise to compelling significant concerns. Fentanyl, heroin, new psychoactive substances and prescribed opioids have been named as the main substances involved in the ‘opioid epidemic’... Read More about Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study.

“He Just Doesn’t Want to Get Out of the Chair and Do It”: The Impact of Apathy in People with Dementia on Their Carers (2021)
Journal Article
Chang, C. Y. M., Baber, W., Dening, T., & Yates, J. (2021). “He Just Doesn’t Want to Get Out of the Chair and Do It”: The Impact of Apathy in People with Dementia on Their Carers. International Journal of Environmental Research and Public Health, 18(12), 6317. https://doi.org/10.3390/ijerph18126317

Apathy, defined as a lack of motivation, is a prevalent and persistent behavioural and psychological symptom of dementia. Limited research suggests that apathy is associated with increased carer burden, but there are no studies investigating carers’... Read More about “He Just Doesn’t Want to Get Out of the Chair and Do It”: The Impact of Apathy in People with Dementia on Their Carers.

Diagnostic, management and nursing challenges of less common dementias: Parkinsonian dementias and Huntington's disease (2021)
Journal Article
Davis, L., & Dening, T. (2021). Diagnostic, management and nursing challenges of less common dementias: Parkinsonian dementias and Huntington's disease. British Journal of Neuroscience Nursing, 17(2), 68-76. https://doi.org/10.12968/bjnn.2021.17.2.68

Abstract Background: Although most cases of dementia are caused by Alzheimer's disease or vascular dementia, around 10-15% of cases are due to other disorders, including dementias with Parkinsonian features, Huntington's disease, frontotemporal d... Read More about Diagnostic, management and nursing challenges of less common dementias: Parkinsonian dementias and Huntington's disease.

‘Less common’ dementias affect many people (2021)
Journal Article
Dening, T., Karim, Z., & Davis, L. (2021). ‘Less common’ dementias affect many people. British Journal of Neuroscience Nursing, 17(2), 53-54. https://doi.org/10.12968/bjnn.2021.17.2.53

t is always unsatisfactory to define things using negative terms, and this is certainly true of ‘less common’ or ‘uncommon’ or ‘rare’ dementias. It is much easier to say what we mean by the term ‘common dementias’, which is that Alzheimer's disease a... Read More about ‘Less common’ dementias affect many people.

The Experience of Apathy in Dementia: A Qualitative Study (2021)
Journal Article
Baber, W., Chang, C. Y. M., Yates, J., & Dening, T. (2021). The Experience of Apathy in Dementia: A Qualitative Study. International Journal of Environmental Research and Public Health, 18(6), Article 3325. https://doi.org/10.3390/ijerph18063325

We aimed to explore and gain an understanding into how people with dementia experience apathy, and consequently suggest effective interventions to help them and their carers. Twelve participants (6 dyads of 6 people with dementia and their family car... Read More about The Experience of Apathy in Dementia: A Qualitative Study.

Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch (2021)
Journal Article
Vinogradova, Y., Dening, T., Hippisley-Cox, J., Taylor, L., Moore, M., & Coupland, C. (2021). Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch. East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series, 38, 1-16

Introduction: Research from clinical trials of hormone replacement therapy (HRT) has produced conflicting findings about possible risks of dementia after receiving these treatments, and further research on HRT and dementia risk has been identified as... Read More about Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch.

How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation (2021)
Journal Article
Devi, R., Chadborn, N. H., Meyer, J., Banerjee, J., Goodman, C., Dening, T., …Gordon, A. L. (2021). How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation. Age and Ageing, 50(4), 1371-1381. https://doi.org/10.1093/ageing/afab007

Background Quality improvement collaboratives (QICs) bring together multidisciplinary teams in a structured process to improve care quality. How QICs can be used to support healthcare improvement in care homes is not fully understood. Methods A... Read More about How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation.

Social connectedness in adults with mental disorders: ecological validation of a conceptual framework for novel complex interventions (2021)
Journal Article
Hare-Duke, L., Dening, T., Oliveira, D., Dewa, R., & Slade, M. (2021). Social connectedness in adults with mental disorders: ecological validation of a conceptual framework for novel complex interventions. Journal of Mental Health, 30(3), 333-340. https://doi.org/10.1080/09638237.2021.1875409

Background Social connectedness interventions may improve the clinical outcomes and personal recovery of adults with mental disorders but many interventions lack a clear theory-base and show limited effectiveness. Aim To evaluate the validity of... Read More about Social connectedness in adults with mental disorders: ecological validation of a conceptual framework for novel complex interventions.

Development of an Evidence-Based Best Practice Model for Teams Managing Crisis in Dementia: Protocol for a Qualitative Study (2021)
Journal Article
Stanyon, M., Streater, A., Coleston-Shields, D., Yates, J., Challis, D., Dening, T., …Orrell, M. (2021). Development of an Evidence-Based Best Practice Model for Teams Managing Crisis in Dementia: Protocol for a Qualitative Study. JMIR Research Protocols, 10(1), Article e14781. https://doi.org/10.2196/14781

Background: Teams working in the community to manage crisis in dementia currently exist, but with widely varying models of practice, it is difficult to determine the effectiveness of such teams. Objective: The aim of this study is to develop a “be... Read More about Development of an Evidence-Based Best Practice Model for Teams Managing Crisis in Dementia: Protocol for a Qualitative Study.

Improving emotional well-being for hospital-based patients with dementia (2020)
Journal Article
Petty, S., Griffiths, A., Coleston, D. M., & Dening, T. (2021). Improving emotional well-being for hospital-based patients with dementia. Quality in Ageing and Older Adults, 22(1), 56-67. https://doi.org/10.1108/QAOA-05-2020-0019

Purpose: Improving hospital care for people with dementia is a well-established priority. There is limited research evidence to guide nursing staff in delivering person-centred care, particularly under conditions where patients are emotionally distre... Read More about Improving emotional well-being for hospital-based patients with dementia.

Understanding the causes, symptoms and effects of young-onset dementia (2020)
Journal Article
Ray, M., & Dening, T. (2021). Understanding the causes, symptoms and effects of young-onset dementia. Nursing Standard, 36(1), 43-50. https://doi.org/10.7748/ns.2020.e11620

Young-onset dementia refers to dementia that develops before the age of 65 years. It can present with a wide variety of symptoms including cognitive, behavioural, neurological and systemic symptoms, which reflects the wide range of possible causes. Y... Read More about Understanding the causes, symptoms and effects of young-onset dementia.

USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER (2020)
Journal Article
Jacinto, A. F., Achterberg, W., Wachholz, P. A., Dening, T., Dening, K. H., Devi, R., …Gordon, A. (2020). USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER. Journal of Nursing Home Research, 6(109-113), https://doi.org/10.14283/jnhrs.2020.28

The Brazilian care home sector is underdeveloped, and the limited available evidence suggests that care quality falls below international standards. Development of the Brazilian care home sector could be associated with better outcomes for those rece... Read More about USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER.

Mild Cognitive Impairment: The Manchester consensus (2020)
Journal Article
Dunne, R. A., Aarsland, D., O'Brien, J. T., Ballard, C., Banerjee, S., Fox, N. C., …Burns, A. (2021). Mild Cognitive Impairment: The Manchester consensus. Age and Ageing, 50(1), 72-80. https://doi.org/10.1093/ageing/afaa228

Given considerable variation in diagnostic and therapeutic practice, there is a need for national guidance on the use of neuroimaging, fluid biomarkers, cognitive testing, follow-up and diagnostic terminology in Mild Cognitive Impairment (MCI). MCI i... Read More about Mild Cognitive Impairment: The Manchester consensus.

Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach (2020)
Journal Article
Yates, J., Stanyon, M., Challis, D., Coleston-Shields, D. M., Dening, T., Hoe, J., …Orrell, M. (2020). Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach. BMC Psychiatry, 20(1), Article 505. https://doi.org/10.1186/s12888-020-02899-0

© 2020, The Author(s). Background: Teams delivering crisis resolution services for people with dementia and their carers provide short-term interventions to prevent admission to acute care settings. There is great variation in these services across t... Read More about Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach.

AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study (2020)
Journal Article
Broome, E. E., Coleston-Shields, D. M., Dening, T., Moniz-Cook, E., Poland, F., Stanyon, M., & Orrell, M. (2020). AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study. JMIR Research Protocols, 9(10), Article e18971. https://doi.org/10.2196/18971

Background: Specialist community teams often support people with dementia who experience crisis. These teams may vary in composition and models of practice, which presents challenges when evaluating their effectiveness. A best practice model for deme... Read More about AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study.