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Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing (2020)
Journal Article
He, C., Korposh, S., Hernandez, F. U., Liu, L., Correia, R., Hayes-Gill, B. R., & Morgan, S. P. (2020). Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing. Sensors, 20(7), Article 1904. https://doi.org/10.3390/s20071904

An optical fibre sensor for monitoring relative humidity (RH) changes during exercise is demonstrated. The humidity sensor comprises a tip coating of poly (allylamine hydrochloride) (PAH)/silica nanoparticles (SiO2 NPs) deposited using the layer-by-l... Read More about Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing.

Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure (2020)
Journal Article
Liu, C., Correia, R., Ballaji, H., Korposh, S., Hayes‐gill, B., & Morgan, S. (2020). Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure. Sensors, 20(5), Article 1388. https://doi.org/10.3390/s20051388

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The widely applied capillary refill time (CRT) measurement is currently performed by manually applying pressure and using a stopwatch to record the time taken for the skin to recover its norma... Read More about Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure.

Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections (2020)
Journal Article
Kurmoo, Y., Hook, A. L., Harvey, D., Dubern, J., Williams, P., Morgan, S. P., …Alexander, M. R. (2020). Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections. Biomaterials Science, 8(5), 1464-1477. https://doi.org/10.1039/c9bm00875f

Real time monitoring of bacterial attachment to medical devices provides opportunities to detect early biofilm formation and instigate appropriate interventions before infection develops. This study utilises long period grating (LPG) optical fibre se... Read More about Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections.

Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide (2019)
Journal Article
Liu, L., Morgan, S. P., Correia, R., Lee, S., & Korposh, S. (2020). Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide. Journal of Lightwave Technology, 38(7), 2037-2045. https://doi.org/10.1109/jlt.2019.2953271

Ammonia (NH3) and carbon dioxide (CO2) are important breath biomarkers for diagnosis of renal and respiratory diseases. Simultaneous sensing of the two gases is useful for assessment of Helicobacter Pylori infection. This study introduces a multi-par... Read More about Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide.

Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging (2019)
Journal Article
Zhang, Q., Grabowska, A. M., Clarke, P. A., & Morgan, S. P. (2019). Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging. Journal of Imaging, 5(11), Article 83. https://doi.org/10.3390/jimaging5110083

he spatial resolution and light detected in fluorescence imaging for small animals are limited by light scattering, absorption and autofluorescence. To address this, novel near-infrared fluorescent contrast agents and imaging configurations have been... Read More about Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging.

Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors (2019)
Journal Article
Hromadka, J., Hazlan, N. N. M., Hernandez, F. U., Correia, R., Norris, A., Morgan, S. P., & Korposh, S. (2019). Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors. Sensors and Actuators B: Chemical, 286, 306 - 314. https://doi.org/10.1016/j.snb.2019.01.124

An array of optical fibre long period gratings (LPGs) has been demonstrated for biomedical application to monitor temperature and relative humidity (RH) changes in the air delivered by a mechanical ventilator operating in different modes. The LPG arr... Read More about Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors.

A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare (2018)
Journal Article
Liu, L., Hao, F., Morgan, S. P., Correia, R., Norris, A., & Korposh, S. (2019). A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare. Sensing and Bio-Sensing Research, 22, Article 100254. https://doi.org/10.1016/j.sbsr.2018.100254

A reflection-mode carbon dioxide (CO2) fibre optic sensor (FOS) is developed based on the colorimetric change of pH indicator dye thymol blue. The CO2 sensing film comprises thymol blue and tetramethylammonium hydroxide in the form of an ion pair dop... Read More about A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare.

Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers (2018)
Journal Article
Yang, Q., Sun, S., Jeffcoate, W., Clark, D., Musgove, A., Game, F., & Morgan, S. (2018). Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers. Journal of Imaging, 4(12), Article 144. https://doi.org/10.3390/jimaging4120144

Diabetic foot ulcers are a major complication of diabetes and present a considerable burden for both patients and health care providers. As healing often takes many months, a method of determining which ulcers would be most likely to heal would be of... Read More about Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers.

Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning (2018)
Conference Proceeding
Yang, S., Zaki, W., Morgan, S., Cho, S., Correia, R., Wen, L., & Zhang, Y. (2018). Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning. In IET Doctoral Forum on Biomedical Engineering, Healthcare, Robotics and Artificial Intelligence 2018 (BRAIN 2018). https://doi.org/10.1049/cp.2018.1721

Blood pressure measurement is a significant part of preventive healthcare and has been widely used in clinical risk and disease management. However, conventional measurement does not provide continuous monitoring and sometimes is inconvenient with a... Read More about Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning.

Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score (2018)
Journal Article
Sinha, R., Correia, R., Gardner, D., Grau-Roma, L., de Brot, S., Hardman, J., …Norris, A. (2018). Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score. Laryngoscope Investigative Otolaryngology, 3(4), 257-262. https://doi.org/10.1002/lio2.168

Objectives: Postintubation laryngotracheal injury is common. Assessment of histopathological changes currently requires animal models. We set about developing a viable, resource effective animal model to study these effects and to develop a detailed... Read More about Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score.

Biomedical application of optical fibre sensors (2018)
Journal Article
Correia, R., James, S., Lee, S., Morgan, S., & Korposh, S. (2018). Biomedical application of optical fibre sensors. Journal of Optics, 20(7), Article 073003. https://doi.org/10.1088/2040-8986/aac68d

Optical fibre sensors(OFS), as a result of their unique properties such as small size, no interference with electromagnetic radiation, high sensitivity and the ability to design multiplexed or distributed sensing systems, have found applications rang... Read More about Biomedical application of optical fibre sensors.

Highly sensitive label-free antibody detection using a long period fibre grating sensor (2018)
Journal Article
Liu, L., Marques, L., Correia, R., Morgan, S. P., Lee, S., Tighe, P. J., …Korposh, S. (2018). Highly sensitive label-free antibody detection using a long period fibre grating sensor. Sensors and Actuators B: Chemical, 271, 24-32. https://doi.org/10.1016/j.snb.2018.05.109

An optical fibre long period grating (LPG) biosensor is appealing in the detection of biomolecules because of the high sensitivity, label-free and real-time measurement. The miniaturized size, ability of remote sensing and immunity to electromagnetic... Read More about Highly sensitive label-free antibody detection using a long period fibre grating sensor.

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media (2018)
Journal Article
Ahmad, J., Jayet, B., Hill, P. J., Mather, M. L., Dehghani, H., & Morgan, S. P. (in press). Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media. Biomedical Optics Express, 9(4), https://doi.org/10.1364/BOE.9.001664

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also d... Read More about Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media.

Incorporation of an ultrasound and model guided permissible region improves quantitative source recovery in bioluminescence tomography (2018)
Journal Article
Jayet, B., Morgan, S. P., & Dehgani, H. (in press). Incorporation of an ultrasound and model guided permissible region improves quantitative source recovery in bioluminescence tomography. Biomedical Optics Express, 9(3), https://doi.org/10.1364/BOE.9.001360

Bioluminescence imaging has shown great potential for studying and monitoring disease progression in small animal pre-clinical imaging. However, absolute bioluminescence source recovery through tomographic multi-wavelength measurements is often hinde... Read More about Incorporation of an ultrasound and model guided permissible region improves quantitative source recovery in bioluminescence tomography.

Highly sensitive volatile organic compounds vapour measurements using a long period grating optical fibre sensor coated with metal organic framework ZIF-8 (2018)
Journal Article
Hromadka, J., Tokay, B., Correia, R., Morgan, S. P., & Korposh, S. (2018). Highly sensitive volatile organic compounds vapour measurements using a long period grating optical fibre sensor coated with metal organic framework ZIF-8. Sensors and Actuators B: Chemical, 260, https://doi.org/10.1016/j.snb.2018.01.015

An optical fibre long period grating (LPG) based volatile organic compound (VOC) sensor coated with ZIF-8, a material from the zeolite imidazolate framework (ZIF) family, functional coating is presented. ZIF-8 film was deposited onto the surface of t... Read More about Highly sensitive volatile organic compounds vapour measurements using a long period grating optical fibre sensor coated with metal organic framework ZIF-8.

Carbon dioxide measurements using long period grating optical fibre sensor coated with metal organic framework HKUST-1 (2017)
Journal Article
Hromadka, J., Tokay, B., Correia, R., Morgan, S. P., & Korposh, S. (2018). Carbon dioxide measurements using long period grating optical fibre sensor coated with metal organic framework HKUST-1. Sensors and Actuators B: Chemical, 255(3), https://doi.org/10.1016/j.snb.2017.09.041

An optical fibre long period grating (LPG) based carbon dioxide (CO2) sensor coated with HKUST-1, a material from the metal organic framework family, functional coating is presented. In-situ crystallization and layer by layer (LbL) techniques of HKUS... Read More about Carbon dioxide measurements using long period grating optical fibre sensor coated with metal organic framework HKUST-1.

Polymeric optical fibre sensor coated by SiO2 nanoparticles for humidity sensing in the skin microenvironment (2017)
Journal Article
Gomez, D., Morgan, S. P., Hayes-Gill, B. R., Correia, R., & Korposh, S. (2018). Polymeric optical fibre sensor coated by SiO2 nanoparticles for humidity sensing in the skin microenvironment. Sensors and Actuators B: Chemical, 254, 887-895. https://doi.org/10.1016/j.snb.2017.07.191

The sensitivity of a low-cost polymeric optical fibre humidity sensor based on transmittance changes due to evanescent wave absorption is reported using test measurements in an environmental chamber and of the skin. The layer-by-layer method was used... Read More about Polymeric optical fibre sensor coated by SiO2 nanoparticles for humidity sensing in the skin microenvironment.

Nanoscale ultrasound-switchable FRET based liposomes for near-infrared fluorescence imaging in optically turbid media (2017)
Journal Article
Zhang, Q., Morgan, S. P., & Mather, M. L. (2017). Nanoscale ultrasound-switchable FRET based liposomes for near-infrared fluorescence imaging in optically turbid media. Small, 13(33), Article 1602895. https://doi.org/10.1002/smll.201602895

A new approach to fluorescence imaging in optically turbid media centered on the use of nanoscale ultrasound-switchable FRET based liposome contrast agents is reported. Liposomes containing lipophilic carbocyanine dyes as FRET pairs with emission wav... Read More about Nanoscale ultrasound-switchable FRET based liposomes for near-infrared fluorescence imaging in optically turbid media.

Ultrasound modulation of bioluminescence generated inside a turbid medium (2017)
Conference Proceeding
Ahmad, J., Jayet, B., Hill, P. J., Mather, M. L., Dehghani, H., & Morgan, S. P. (2017). Ultrasound modulation of bioluminescence generated inside a turbid medium. In A. A. Oraevsky, & L. V. Wang (Eds.), Proceedings SPIE 10064: Photons Plus Ultrasound: Imaging and Sensing 2017. https://doi.org/10.1117/12.2251349

In vivo bioluminescence imaging (BLI) has poor spatial resolution owing to strong light scattering by tissue, which also affects quantitative accuracy. This paper proposes a hybrid acousto-optic imaging platform that images bioluminescence modulated... Read More about Ultrasound modulation of bioluminescence generated inside a turbid medium.