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Using nicotine replacement therapy for smoking reduction in pregnancy: a qualitative study of pregnant women in the UK who smoke (2024)
Journal Article
Thomson, R., Phillips, L., Orton, S., Naughton, F., & Coleman, T. (2024). Using nicotine replacement therapy for smoking reduction in pregnancy: a qualitative study of pregnant women in the UK who smoke. BMJ Open, 14(8), Article e085945. https://doi.org/10.1136/bmjopen-2024-085945

Objectives To explore the acceptability and perceived motivations and barriers of using nicotine replacement therapy (NRT) to reduce the number of daily cigarettes smoked in pregnancy, rather than for stopping completely.

Design Telephone, semi-st... Read More about Using nicotine replacement therapy for smoking reduction in pregnancy: a qualitative study of pregnant women in the UK who smoke.

Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers (2024)
Journal Article
Belderson, P., McDaid, L., Emery, J., Coleman, T., Leonardi-Bee, J., & Naughton, F. (2024). Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers. Nicotine and Tobacco Research, Article ntae184. https://doi.org/10.1093/ntr/ntae184

Introduction

Unsupported attempts to quit smoking during pregnancy have a low success rate. Chances of quitting successfully are higher with an interpersonal treatment programme but there is low uptake of this in the United Kingdom (UK). Deliverin... Read More about Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers.

Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy (2024)
Journal Article
Clark, M. M., Cooper, S., Naughton, F., Ussher, M., Emery, J., McDaid, L., Thomson, R., Phillips, L., Bauld, L., Aveyard, P., Torgerson, D., Berlin, I., Lewis, S., Parrott, S., Hewitt, C., Welch, C., Parkinson, G., Dickinson, A., Sutton, S., Brimicombe, J., …Coleman, T. (2024). Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy. BMJ Open, 14(5), Article e087175. https://doi.org/10.1136/bmjopen-2024-087175

IntroductionSmoking during pregnancy is harmful to unborn babies, infants and women. Nicotine replacement therapy (NRT) is offered as the usual stop-smoking support in the UK. However, this is often used in insufficient doses, intermittently or for t... Read More about Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy.

A smoking cessation smartphone app that delivers real-time 'context aware' behavioural support: the Quit Sense feasibility RCT. (2024)
Journal Article
Naughton, F., Hope, A., Siegele-Brown, C., Grant, K., Notley, C., Colles, A., …High, J. (2024). A smoking cessation smartphone app that delivers real-time 'context aware' behavioural support: the Quit Sense feasibility RCT. Public Health Research, 12(4), 1-99. https://doi.org/10.3310/KQYT5412

During a quit attempt, cues from a smoker's environment are a major cause of brief smoking lapses, which increase the risk of relapse. Quit Sense is a theory-guided Just-In-Time Adaptive Intervention smartphone app, providing smokers with the means t... Read More about A smoking cessation smartphone app that delivers real-time 'context aware' behavioural support: the Quit Sense feasibility RCT..

Effect of 3 months and 12 months of financial incentives on 12‐month postpartum smoking cessation maintenance: A randomized controlled trial (2024)
Journal Article
Ussher, M., Best, C., Lewis, S., McKell, J., Coleman, T., Cooper, S., …Bauld, L. (2024). Effect of 3 months and 12 months of financial incentives on 12‐month postpartum smoking cessation maintenance: A randomized controlled trial. Addiction, 119(8), 1352-1363. https://doi.org/10.1111/add.16487

Background and aims

Offering financial incentives is effective for smoking cessation during pregnancy. We tested the effectiveness of financial incentives for maintaining postpartum cessation, comparing 12-month and 3-month incentives with each ot... Read More about Effect of 3 months and 12 months of financial incentives on 12‐month postpartum smoking cessation maintenance: A randomized controlled trial.

Effect of 3 months and 12 months of financial incentives on 12-month postpartum smoking cessation maintenance: a randomised controlled trial (2024)
Journal Article
Lewis, S., Mckell, J., Coleman, T., Cooper, S., Orton, S., Bauld, L., & Usher, J. (2024). Effect of 3 months and 12 months of financial incentives on 12-month postpartum smoking cessation maintenance: a randomised controlled trial. Addiction, 119(8), 1352-1363. https://doi.org/10.1111/add.16487

Background and aims
Offering financial incentives is effective for smoking cessation during pregnancy. We tested the effectiveness of financial incentives for maintaining postpartum cessation, comparing 12-month and 3-month incentives with each othe... Read More about Effect of 3 months and 12 months of financial incentives on 12-month postpartum smoking cessation maintenance: a randomised controlled trial.

Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention (2024)
Journal Article
McDaid, L., Belderson, P., Emery, J., Coleman, T., Leonardi-Bee, J., & Naughton, F. (in press). Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention. PLOS Digital Health, 3(3), Article e0000472. https://doi.org/10.1371/journal.pdig.0000472

Many pregnant smokers need support to quit successfully. In the United Kingdom, trained smoking cessation advisors deliver structured behavioural counselling alongside access to free nicotine replacement therapy (NRT); known as the ‘Standard Treatmen... Read More about Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention.

The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action (2024)
Journal Article
Emery, J., Leonardi-Bee, J., Coleman, T., McDaid, L., & Naughton, F. (2024). The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action. Nicotine & Tobacco Research, 26(8), 1072-1080. https://doi.org/10.1093/ntr/ntae026

Introduction
Digital cessation support appeals to pregnant smokers. In two pooled RCTs, MiQuit, a pregnancy-specific tailored text messaging intervention, did not show effectiveness for validated prolonged abstinence. However, secondary outcomes and... Read More about The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action.

Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial (2024)
Journal Article
Pesola, F., Smith, K. M., Phillips-Waller, A., Przulj, D., Griffiths, C., Walton, R., …Hajek, P. (2024). Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial. Addiction, 119(5), 875-884. https://doi.org/10.1111/add.16422

Aims

To examine safety of e-cigarettes (EC) and nicotine patches (NRT) when used to help pregnant smokers quit.

Design

A recent trial of EC versus NRT reported safety outcomes in the randomised arms. We conducted a further analysis based... Read More about Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial.

Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial (2024)
Journal Article
Pesola, F., Smith, K. M., Phillips‐Waller, A., Przulj, D., Griffiths, C., Walton, R., …Hajek, P. (2024). Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial. Addiction, 119(5), 875-884. https://doi.org/10.1111/add.16422

Aims: The aim of this study was to examine the safety of e-cigarettes (EC) and nicotine patches (NRT) when used to help pregnant smokers quit. Design: A recent trial of EC versus NRT reported safety outcomes in the randomized arms. We conducted a fur... Read More about Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial.

The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study (2023)
Journal Article
Orton, S., Szatkowski, L., Naughton, F., Coleman, T., Clark, M., Cooper, S., …Thomson, R. (2024). The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study. Nicotine and Tobacco Research, 26(2), 212-219. https://doi.org/10.1093/ntr/ntad140

Introduction For non-pregnant people unable to quit smoking, the NHS recommends nicotine replacement therapy (NRT) for smoking reduction. This is not recommended during pregnancy due to concerns about higher nicotine intake than smoking alone. We inv... Read More about The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study.

Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy (2023)
Journal Article
Przulj, D., Pesola, F., Myers Smith, K., McRobbie, H., Coleman, T., Lewis, S., …Hajek, P. (2023). Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy. Health Technology Assessment, 27(13), https://doi.org/10.3310/AGTH6901

Background
Some pregnant smokers try e-cigarettes, but effectiveness and safety of such use are unknown.

Objectives
To compare effectiveness and safety of nicotine patches and e-cigarettes in pregnancy.

Design
A pragmatic multi-centre random... Read More about Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy.

Systematic review and meta‐analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy (2023)
Journal Article
Podlasek, A., Claire, R., Campbell, K. A., Orton, S., Thomson, R., & Coleman, T. (2023). Systematic review and meta‐analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy. Addiction, 118(11), 2076-2092. https://doi.org/10.1111/add.16279

Aims: To determine effects of concurrent smoking and nicotine replacement therapy (NRT) use on reported heaviness of smoking, nicotine (cotinine) body fluid and exhaled air carbon monoxide (CO) concentrations. Methods: Systematic review and meta‐anal... Read More about Systematic review and meta‐analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy.

Systematic review and meta-analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy (2023)
Journal Article
Podlasek, A., Clair, R., Campbell, K. A., Orton, S., Thomson, R., & Coleman, T. (2023). Systematic review and meta-analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy. Addiction, 118(11), 2076-2092. https://doi.org/10.1111/add.16279

Aims
To determine effects of concurrent smoking and nicotine replacement therapy (NRT) use on reported heaviness of smoking, nicotine (cotinine) body fluid and exhaled air carbon monoxide (CO) concentrations.

Methods
Systematic review and meta-a... Read More about Systematic review and meta-analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy.

Development of “Baby, Me, & NRT”: A Behavioral Intervention to Improve the Effectiveness of Nicotine Replacement Therapy in Pregnancy (2023)
Journal Article
McDaid, L., Emery, J., Thomson, R., Coleman, T., Cooper, S., Dickinson, A., …Naughton, F. (2023). Development of “Baby, Me, & NRT”: A Behavioral Intervention to Improve the Effectiveness of Nicotine Replacement Therapy in Pregnancy. Nicotine and Tobacco Research, 25(11), 1770-1780. https://doi.org/10.1093/ntr/ntad102

Background
The effectiveness of Nicotine Replacement Therapy (NRT) for smoking cessation in pregnancy is limited by inconsistent and incorrect use. This paper describes the development process for “Baby, Me, & NRT”, a novel pregnancy-specific interv... Read More about Development of “Baby, Me, & NRT”: A Behavioral Intervention to Improve the Effectiveness of Nicotine Replacement Therapy in Pregnancy.

An Automated, Online Feasibility Randomized Controlled Trial of a Just-In-Time Adaptive Intervention for Smoking Cessation (Quit Sense) (2023)
Journal Article
Naughton, F., Hope, A., Siegele-Brown, C., Grant, K., Barton, G., Notley, C., …High, J. (2023). An Automated, Online Feasibility Randomized Controlled Trial of a Just-In-Time Adaptive Intervention for Smoking Cessation (Quit Sense). Nicotine and Tobacco Research, 25(7), 1319-1329. https://doi.org/10.1093/ntr/ntad032

Introduction: Learned smoking cues from a smoker's environment are a major cause of lapse and relapse. Quit Sense, a theory-guided Just-In-Time Adaptive Intervention smartphone app, aims to help smokers learn about their situational smoking cues and... Read More about An Automated, Online Feasibility Randomized Controlled Trial of a Just-In-Time Adaptive Intervention for Smoking Cessation (Quit Sense).

Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy (2023)
Journal Article
Emery, J., Mcdaid, L., Coleman, T., Cooper, S., Thomson, R., Kinahan-Goodwin, D., …Naughton, F. (2023). Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy. Nicotine and Tobacco Research, 25(7), 1310-1318. https://doi.org/10.1093/ntr/ntad030

Introduction
Improving adherence to nicotine replacement therapy (NRT) in pregnancy may result in higher smoking cessation rates. Informed by the Necessities and Concerns Framework, we developed an intervention targeting pregnancy NRT adherence. To... Read More about Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy.

Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. (2022)
Journal Article
Shoesmith, E., Huddlestone, L., Pervin, J., Shahab, L., Coventry, P., Coleman, T., …Ratschen, E. (2023). Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. Nicotine & Tobacco Research, 25(4), 729-737. https://doi.org/10.1093/ntr/ntac242

Evidence suggests that smokers can successfully quit, remain abstinent or reduce smoking during a smokefree mental health inpatient stay, provided behavioural/pharmacological support are offered. However, few evidence-based strategies to prevent the... Read More about Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel..

Investigating the cost-effectiveness of three cessation interventions on a national scale using the Economics of Smoking in Pregnancy (ESIP) decision analytical model (2022)
Journal Article
Jones, M., Smith, M., Lewis, S., Parrott, S., & Coleman, T. (2022). Investigating the cost-effectiveness of three cessation interventions on a national scale using the Economics of Smoking in Pregnancy (ESIP) decision analytical model. Addiction, https://doi.org/10.1111/add.15968

Aim: To measure the cost-effectiveness of adding text message (TMB), exercise (EB) and abstinent-contingent financial incentive-based (CFIB) stop smoking interventions to standard smoking cessation support for pregnant women in England. Design: Model... Read More about Investigating the cost-effectiveness of three cessation interventions on a national scale using the Economics of Smoking in Pregnancy (ESIP) decision analytical model.

Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial (2022)
Journal Article
Hajek, P., Przulj, D., Pesola, F., Griffiths, C., Walton, R., McRobbie, H., …Myers Smith, K. (2022). Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial. Nature Medicine, 28(5), 958-964. https://doi.org/10.1038/s41591-022-01808-0

Nicotine replacement therapy, in the form of nicotine patches, is commonly offered to pregnant women who smoke to help them to stop smoking, but this approach has limited efficacy in this population. Electronic cigarettes (e-cigarettes) are also used... Read More about Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial.