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Multiparametric measurement of cerebral physiology using calibrated fMRI (2017)
Journal Article
Bright, M. G., Croal, P. L., Blockley, N. P., & Bulte, D. P. (2019). Multiparametric measurement of cerebral physiology using calibrated fMRI. NeuroImage, 187, 128-144. https://doi.org/10.1016/j.neuroimage.2017.12.049

The ultimate goal of calibrated fMRI is the quantitative imaging of oxygen metabolism (CMRO2), and this has been the focus of numerous methods and approaches. However, one underappreciated aspect of this quest is that in the drive to measure CMRO2, m... Read More about Multiparametric measurement of cerebral physiology using calibrated fMRI.

Field strength dependence of grey matter R2* on venous oxygenation (2016)
Journal Article
Croal, P. L., Driver, I. D., Francis, S. T., & Gowland, P. A. (2017). Field strength dependence of grey matter R2* on venous oxygenation. NeuroImage, 146, 327-332. https://doi.org/10.1016/j.neuroimage.2016.10.004

The relationship between venous blood oxygenation and change in transverse relaxation rate (?R2 *) plays a key role in calibrated BOLD fMRI. This relationship, defined by the parameter ?, has previously been determined using theoretical simulations a... Read More about Field strength dependence of grey matter R2* on venous oxygenation.

The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG (2015)
Journal Article
Croal, P. L., Hall, E. L., Driver, I. D., Brookes, M. J., Gowland, P. A., & Francis, S. T. (2015). The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG. NeuroImage, 105, https://doi.org/10.1016/j.neuroimage.2014.10.036

The physiological effect of hyperoxia has been poorly characterised, with studies reporting conflicting results on the role of hyperoxia as a vasoconstrictor. It is not clear whether hyperoxia is the primary contributor to vasoconstriction or whether... Read More about The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG.