Coordinated prefrontal state transition leads extinction of reward-seeking behaviors
(2021)
Journal Article
Russo, E., Ma, T., Spanagel, R., Durstewitz, D., Toutounji, H., & Köhr, G. (2021). Coordinated prefrontal state transition leads extinction of reward-seeking behaviors. Journal of Neuroscience, 41(11), 2406-2419. https://doi.org/10.1523/jneurosci.2588-20.2021
Extinction learning suppresses conditioned reward responses and is thus fundamental to adapt to changing environmental demands and to control excessive reward seeking. The medial prefrontal cortex (mPFC) monitors and controls conditioned reward respo... Read More about Coordinated prefrontal state transition leads extinction of reward-seeking behaviors.