Skip to main content

Research Repository

Advanced Search

All Outputs (221)

Critical Psychiatry (2007)
Journal Article
Middleton, H. (2007). Critical Psychiatry. Mental Health Review Journal, 12,

Critical psychiatry appraises and comments upon psychiatric services as they are usually provided. This article, prompted by the publication of a recent book, considers the place of critical psychiatry historically and in the context of contemporar... Read More about Critical Psychiatry.

National evaluation of NHS genetics service investments: emerging issues from the cancer genetics pilots (2007)
Journal Article
Martin, G. P., Finn, R., & Currie, G. (2007). National evaluation of NHS genetics service investments: emerging issues from the cancer genetics pilots. Familial Cancer, 6(2), https://doi.org/10.1007/s10689-007-9130-3

In seeking to fulfil the ambition of the 2003 genetics white paper, Our Inheritance, Our Future, to ‘mainstream’ genetic knowledge and practices, the Department of Health provided start-up funding for pilot services in various clinical areas, includi... Read More about National evaluation of NHS genetics service investments: emerging issues from the cancer genetics pilots.

The Virtual International Stroke Trials Archive (2007)
Journal Article
Myzoon, A., Bath, P. M., Curram, J., Davis, S. M., Diener, H., Donnan, G. A., …Lees, K. R. (2007). The Virtual International Stroke Trials Archive. Stroke, 38(6),

Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for r... Read More about The Virtual International Stroke Trials Archive.

A Utilitarian Perspective of Social and Medical Contributions to Three Illustrative Conditions, and Recent UK NHS Policy Initiatives (2007)
Journal Article
Middleton, H., & Shaw, I. (2007). A Utilitarian Perspective of Social and Medical Contributions to Three Illustrative Conditions, and Recent UK NHS Policy Initiatives. Journal of Mental Health, 16(3),

Background: To date debate concerning the relative merits of social and medical sciences has been largely academic. Aims: To outline and critically appraise a utilitarian approach to mental health research that reflects a critical realist perspect... Read More about A Utilitarian Perspective of Social and Medical Contributions to Three Illustrative Conditions, and Recent UK NHS Policy Initiatives.

Bacteriophage therapy to reduce Salmonella colonization of broiler chickens (2007)
Journal Article
Atterbury, R. J., Van Bergen, M., Ortiz, F., Lovell, M., Harris, J., De Boer, A., …Barrow, P. (2007). Bacteriophage therapy to reduce Salmonella colonization of broiler chickens. Applied and Environmental Microbiology, 73(14), https://doi.org/10.1128/AEM.00049-07

Acute enteric infections caused by salmonellas remain a major public health burden worldwide. Poultry, particularly chickens, are known to be the main reservoir for this zoonotic pathogen. Although some progress has been made in reducing Salmonella c... Read More about Bacteriophage therapy to reduce Salmonella colonization of broiler chickens.

Self-reported efficacy of an online dental anxiety support group: A pilot study (2007)
Journal Article
Coulson, N. S., & Buchanan, H. (2008). Self-reported efficacy of an online dental anxiety support group: A pilot study. Community Dentistry and Oral Epidemiology, 36(1), 43-46. https://doi.org/10.1111/j.1600-0528.2007.00349.x

This study aimed to explore the self-reported effectiveness of an existing online dental anxiety support group in terms of perceived level of anxiety since accessing the group. An online questionnaire was completed by 91 individuals who accessed the... Read More about Self-reported efficacy of an online dental anxiety support group: A pilot study.

Should eye protection be worn during dermatological surgery: prospective observational study (2007)
Journal Article
Birnie, A., Thomas, K., & Varma, S. (2007). Should eye protection be worn during dermatological surgery: prospective observational study. British Journal of Dermatology, 156(6), https://doi.org/10.1111/j.1365-2133.2007.07930.x

Background There is a potential risk of infection with blood-borne viruses if a doctor receives a blood splash to a mucous membrane. The quantification of facial contamination with blood has never been documented in the context of dermatological sur... Read More about Should eye protection be worn during dermatological surgery: prospective observational study.

Randomized controlled trial of the intraligamental use of a local anaesthetic (lignocaine 2%) versus controls in paediatric tooth extraction (2007)
Journal Article
Sammons, H. M., Unsworth, . V., Gray, C., Choonara, I., Cherrill, . J., & Quirke, W. (2007). Randomized controlled trial of the intraligamental use of a local anaesthetic (lignocaine 2%) versus controls in paediatric tooth extraction. International Journal of Paediatric Dentistry, 17(4), 297-303. https://doi.org/10.1111/j.1365-263x.2007.00832.x

Background. Children still experience pain upon waking following dental extraction under general anaesthesia. Local anaesthetic has been shown to reduce this pain, but needs to be administered via a method that causes minimum injury or distress to th... Read More about Randomized controlled trial of the intraligamental use of a local anaesthetic (lignocaine 2%) versus controls in paediatric tooth extraction.

Dynamic instabilities in scalar neural field equations with space-dependent delays (2007)
Journal Article
Venkov, N. A., Coombes, S., & Matthews, P. C. (2007). Dynamic instabilities in scalar neural field equations with space-dependent delays. Physica D: Nonlinear Phenomena, 232(1), 1-15. https://doi.org/10.1016/j.physd.2007.04.011

In this paper we consider a class of scalar integral equations with a form of space-dependent delay. These nonlocal models arise naturally when modelling neural tissue with active axons and passive dendrites. Such systems are known to support a dynam... Read More about Dynamic instabilities in scalar neural field equations with space-dependent delays.

Rule Generalisation in Intrusion Detection Systems using Snort (2007)
Journal Article
Aickelin, U., Twycross, J., & Hesketh-Roberts, T. (2007). Rule Generalisation in Intrusion Detection Systems using Snort. International Journal of Electronic Security and Digital Forensics, 1(1), 101-116. https://doi.org/10.1504/IJESDF.2007.013596

Intrusion Detection Systems (IDSs) provide an important layer of security for computer systems and networks, and are becoming more and more necessary as reliance on Internet services increases and systems with sensitive data are more commonly open to... Read More about Rule Generalisation in Intrusion Detection Systems using Snort.

Organisational justice and smoking: the Finnish Public Sector Study (2007)
Journal Article
Kouvonen, A., Vahtera, J., Elovainio, M., Cox, S. J., Cox, T., Linna, A., …Kivimaki, M. (2007). Organisational justice and smoking: the Finnish Public Sector Study

Study Objective: To examine the extent to which justice of decision-making procedures and interpersonal relations is associated with smoking. Setting: Ten municipalities and 21 hospitals in Finland. Design and Participants: Cross-sectional data der... Read More about Organisational justice and smoking: the Finnish Public Sector Study.

Modelling windage power loss from an enclosed spur gear (2007)
Journal Article
Eastwick, C., Simmons, K., & Al-Shibl, K. (2007). Modelling windage power loss from an enclosed spur gear. Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, 221(3), https://doi.org/10.1243/09576509JPE344

Within a gearbox the majority of transmission losses can be attributed to bearing losses, meshing losses, or losses due to windage/churning. In this paper the commercial computational fluid dynamics (CFD) code Fluent 6.2.16 is applied in a two-dimens... Read More about Modelling windage power loss from an enclosed spur gear.

The effect of striatal dopamine depletion and the adenosine A2A antagonist KW-6002 on reversal learning in rats (2007)
Journal Article
O’Neill, M., & Brown, V. J. (2007). The effect of striatal dopamine depletion and the adenosine A2A antagonist KW-6002 on reversal learning in rats. Neurobiology of Learning and Memory, 88(1), 75-81. https://doi.org/10.1016/j.nlm.2007.03.003

This study assessed whether dopamine in the dorsomedial striatum is necessary for flexible adaptation to changes in stimulus–response contingencies. As KW-6002 (Istradefylline), an adenosine A2A antagonist, improves motor deficits resulting from stri... Read More about The effect of striatal dopamine depletion and the adenosine A2A antagonist KW-6002 on reversal learning in rats.

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials (2007)
Journal Article
Bath, P. M., & Optimising Analysis of Stroke Trials Collaboration, O. (2007). Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials. Stroke, 38(6), https://doi.org/10.1161/STROKEAHA.106.474080

Background and Purpose—Most large acute stroke trials have been neutral. Functional outcome is usually analyzed usinga yes or no answer, eg, death or dependency versus independence. We assessed which statistical approaches are mostefficient in analyz... Read More about Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials.

Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3 (2007)
Journal Article
Lane, J. R., Powney, B., Wise, A., Rees, S., & Milligan, G. (2007). Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3. Molecular Pharmacology, 71(5), 1349-1359. https://doi.org/10.1124/mol.106.032722

A range of ligands displayed agonism at the long isoform of the human dopamine D(2) receptor, whether using receptor-G protein fusions or membranes of cells in which pertussis toxin-resistant mutants of individual Galpha(i)-family G proteins could be... Read More about Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

Factors affecting participation in Sure Start programmes: a qualitative investigation of parents' views. (2007)
Journal Article
Avis, M., Bulman, D., & Leighton, P. (2007). Factors affecting participation in Sure Start programmes: a qualitative investigation of parents' views. Health and Social Care in the Community, 15(3), 203-211. https://doi.org/10.1111/j.1365-2524.2006.00673.x

The objectives of the present study were to examine the factors that parents identify as promoting or hindering participation in Sure Start programmes, and to identify methods for enhancing parents’ engagement with Sure Start. A qualitative, in-depth... Read More about Factors affecting participation in Sure Start programmes: a qualitative investigation of parents' views..

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis (2007)
Journal Article
Rioux, J. D., Xavier, R. J., Taylor, K. D., Silverberg, M. S., Goyette, P., Huett, A., …Brant, S. R. (2007). Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nature Genetics, 39(5), 596-604. https://doi.org/10.1038/ng2032

We present a genome-wide association study of ileal Crohn disease and two independent replication studies that identify several new regions of association to Crohn disease. Specifically, in addition to the previously established CARD15 and IL23R asso... Read More about Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.