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UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI) (2024)
Journal Article
McClaughlin, E., Elliott, S., Jewitt, S., Smallman-Raynor, M., Dunham, S., Parnell, T., …Tarlinton, R. (2024). UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI). Preventive Veterinary Medicine, 224, Article 106117. https://doi.org/10.1016/j.prevetmed.2024.106117

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI).

Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK (2024)
Journal Article
Jewitt, S., McClaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK. Veterinary Record, Article e3713. https://doi.org/10.1002/vetr.3713

Background: The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented. Methods: An online survey was designed to explore veterinarians’ experiences of and confidence in treatin... Read More about Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK.

Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom (2024)
Journal Article
Jewitt, S., Mcclaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (in press). Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom. Veterinary Record, Article e3713

Background The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented. Methods An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom.

Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China (2024)
Journal Article
Baker, M., Zhang, X., Maciel-Guerra, A., Babaarslan, K., Dong, Y., Wang, W., …Dottorini, T. (2024). Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China. Nature Communications, 15, Article 206. https://doi.org/10.1038/s41467-023-44272-1

Sharing of genetic elements among different pathogens and commensals inhabiting same hosts and environments has significant implications for antimicrobial resistance (AMR), especially in settings with high antimicrobial exposure. We analysed 661 Esch... Read More about Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China.

Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis (2024)
Journal Article
Yan, W. L., Sun, H. T., Zhao, Y. C., Hou, X. W., Zhang, M., Zhao, Q., …Ni, H. B. (2024). Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis. Research in Veterinary Science, 168, Article 105136. https://doi.org/10.1016/j.rvsc.2024.105136

Avian malaria is a vector-borne parasitic disease caused by Plasmodium infection transmitted to birds by mosquitoes. The aim of this systematic review was to analyze the global prevalence of malaria and risk factors associated with infection in wild... Read More about Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis.

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Palomino Lago, E., Baird, A., Blott, S. C., McPhail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2024). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), Article 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms under... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence (2023)
Journal Article
Liang, Q. L., Nie, L. B., Elsheikha, H. M., Li, T. T., Sun, L. X., Zhang, Z. W., …Wang, J. L. (2023). The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence. PLoS Pathogens, 19(12), Article e1011831. https://doi.org/10.1371/journal.ppat.1011831

Protein phosphatases are post-translational regulators of Toxoplasma gondii proliferation, tachyzoite-bradyzoite differentiation and pathogenesis. Here, we identify the putative protein phosphatase 6 (TgPP6) subunits of T. gondii and elucidate their... Read More about The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence.

Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. (2023)
Journal Article
Leach, K. A., Holsey, H. J., Bradley, A. J., & Green, M. J. (2023). Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. Veterinary Record, Article e3605. https://doi.org/10.1002/vetr.3605

Background: Achieving a reduction in mastitis in dairy cows is a common industry goal, but there is no recent peer-reviewed record of progress in the UK. Methods: A convenience sample of 125 herds in England and Scotland was recruited based on the qu... Read More about Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021..

The splicing factor SR2 is an important virulence factor of Toxoplasma gondii (2023)
Journal Article
Wu, X., Nanzheng, X., Elsheikha, H. M., Li, T., Kou, Y., & Zhu, X. (2023). The splicing factor SR2 is an important virulence factor of Toxoplasma gondii. Frontiers in Microbiology, 14, Article 1302512. https://doi.org/10.3389/fmicb.2023.1302512

Serine/arginine-rich (SR) proteins are key factors with important roles in constitutive and alternative splicing (AS) of pre-mRNAs. However, the role of SR splicing factors in the pathogenicity of T. gondii remains largely unexplored. Here, we invest... Read More about The splicing factor SR2 is an important virulence factor of Toxoplasma gondii.

Prospective case study of critical decision making for horses referred for treatment of colic (2023)
Journal Article
Burrell, K., Sutton‐Walker, G., England, G. C. W., Burford, J. H., & Freeman, S. L. (2023). Prospective case study of critical decision making for horses referred for treatment of colic. Veterinary Record, Article e3615. https://doi.org/10.1002/vetr.3615

Background There is limited evidence on factors affecting critical decision making for horses with colic. This study's aim was to describe the assessment and decision making involved in horses referred for management of colic. Methods An in-dept... Read More about Prospective case study of critical decision making for horses referred for treatment of colic.

Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions (2023)
Journal Article
Roque, F. D. O., Bellón, B., Guerra, A., Valente-Neto, F., Santos, C. C., Melo, I., …Ochoa-Quintero, J. M. (2023). Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions. Frontiers in Veterinary Science, 10, Article 1229676. https://doi.org/10.3389/fvets.2023.1229676

The need to reconcile food production, the safeguarding of nature, and the protection of public health is imperative in a world of continuing global change, particularly in the context of risks of emerging zoonotic disease (EZD). In this paper, we ex... Read More about Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions.

Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study (2023)
Journal Article
Gibson, J., Brennan, M. L., Oxtoby, C., Mossop, L., & White, K. (2023). Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study. Veterinary Record, 193(12), Article e3601. https://doi.org/10.1002/vetr.3601

Background Understanding ethical challenges experienced in relation to adverse events is necessary to inform strategies that optimise patient safety and practitioner wellbeing. Methods A qualitative exploration of UK veterinary practitioners’ ex... Read More about Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study.

Pseudomonas spp. in Canine Otitis Externa (2023)
Journal Article
Secker, B., Shaw, S., & Atterbury, R. J. (2023). Pseudomonas spp. in Canine Otitis Externa. Microorganisms, 11(11), Article 2650. https://doi.org/10.3390/microorganisms11112650

Canine otitis externa (OE) is a commonly diagnosed condition seen in veterinary practice worldwide. In this review, we discuss the mechanisms of the disease, with a particular focus on the biological characteristics of Pseudomonas aeruginosa and the... Read More about Pseudomonas spp. in Canine Otitis Externa.

Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression (2023)
Journal Article
Atallah, N. M., Haque, M., Quinn, C., Toss, M. S., Makhlouf, S., Ibrahim, A., …Rakha, E. (2023). Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression. European Journal of Cancer, 195, Article 113371. https://doi.org/10.1016/j.ejca.2023.113371

Background: Breast cancer (BC) expressing low levels of human epidermal growth factor receptor 2 (HER2 Low) is an emerging category that needs further refining. This study aims to provide a comprehensive clinico-pathological and molecular profile of... Read More about Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression.

Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection (2023)
Journal Article
Occhiuto, F., Vázquez-Diosdado, J. A., King, A. J., & Kaler, J. (2023). Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection. Scientific Reports, 13, Article 18243. https://doi.org/10.1038/s41598-023-44957-z

Individual consistency in behaviour, known as animal personality, and behavioural plasticity in response to environmental changes are important factors shaping individual behaviour. Correlations between them, called personality-dependent plasticity,... Read More about Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection.

A newly characterized dense granule protein (GRA76) is important for the growth and virulence of Toxoplasma gondii (2023)
Journal Article
Zheng, X., Sun, L., Elsheikha, H. M., Li, T., Gao, J., Wu, X., …Wang, J. (2024). A newly characterized dense granule protein (GRA76) is important for the growth and virulence of Toxoplasma gondii. International Journal for Parasitology, 54(2), 109-121. https://doi.org/10.1016/j.ijpara.2023.09.001

Pathogenicity of the zoonotic pathogen Toxoplasma gondii largely depends on the secretion of effector proteins into the extracellular milieu and host cell cytosol, including the dense granule proteins (GRAs). The protein-encoding gene TGME49_299780 w... Read More about A newly characterized dense granule protein (GRA76) is important for the growth and virulence of Toxoplasma gondii.

Exploring the data divide through a social practice lens: A qualitative study of UK cattle farmers (2023)
Journal Article
Doidge, C., Palczynski, L., Zhou, X., Bearth, A., van Schaik, G., & Kaler, J. (2023). Exploring the data divide through a social practice lens: A qualitative study of UK cattle farmers. Preventive Veterinary Medicine, 220, Article 106030. https://doi.org/10.1016/j.prevetmed.2023.106030

Appropriate management decisions are key for sustainable and profitable beef and dairy farming. Data-driven technologies aim to provide information which can improve farmers’ decision-making practices. However, data-driven technologies have resulted... Read More about Exploring the data divide through a social practice lens: A qualitative study of UK cattle farmers.

Antiviral activity of salt-coated materials against SARS-CoV-2 (2023)
Journal Article
Coleman, C. M., Wang, B., Wang, Y., Tapia-Brito, E., Chen, Z., Riffat, J., …Ghaemmaghami, A. (2023). Antiviral activity of salt-coated materials against SARS-CoV-2. Access Microbiology, 5(9), Article 000492. https://doi.org/10.1099/acmi.0.000492.v5

The SARS-CoV-2 pandemic demonstrated the importance of human coronaviruses and the need to develop materials to prevent the spread of emergent respiratory viruses. Coating of surfaces with antiviral materials is a major interest in controlling spread... Read More about Antiviral activity of salt-coated materials against SARS-CoV-2.

Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions (2023)
Journal Article
Dlamini, S. B., Gigante, A. M., Hooton, S. P. T., & Atterbury, R. J. (2023). Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions. Microorganisms, 11(10), Article 2389. https://doi.org/10.3390/microorganisms11102389

Salmonella causes a range of diseases in humans and livestock of considerable public health and economic importance. Widespread antimicrobial use, particularly in intensively produced livestock (e.g., poultry and pigs) may contribute to the rise of m... Read More about Efficacy of Different Encapsulation Techniques on the Viability and Stability of Diverse Phage under Simulated Gastric Conditions.