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Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray (2012)
Journal Article
Fabi, J. P., Seymour, G. B., Graham, N. S., Broadley, M. R., May, S., Lajolo, F. M., …Oliveira do Nascimento, J. R. (in press). Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray. BMC Plant Biology, 12, Article 242. https://doi.org/10.1186/1471-2229-12-242

Background Papaya (Carica papaya L.) is a commercially important crop that produces climacteric fruits with a soft and sweet pulp that contain a wide range of health promoting phytochemicals. Despite its importance, little is known about transcrip... Read More about Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray.

Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem (2012)
Journal Article
Beale, K., Gardiner, J., Bewick, G., Hostomska, K., Patel, N., Hussain, S., …Dhillo, W. (2013). Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem. British Journal of Pharmacology, 168(2), 403-410. https://doi.org/10.1111/j.1476-5381.2012.02191.x

Background and Purpose Prokineticin 2 (PK2) has recently been shown to acutely reduce food intake in rodents. We aimed to determine the CNS sites and receptors that mediate the anorectic effects of peripherally administered PK2 and its chronic effect... Read More about Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem.

Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial (2012)
Journal Article
Patel, M., Pilcher, J., Travers, J., Perrin, K., Shaw, D., Black, P., …Beasley, R. (2013). Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial. Journal of Allergy and Clinical Immunology: In Practice, 1(1), https://doi.org/10.1016/j.jaip.2012.08.004

Background Electronic monitoring of inhaled asthma medications is one method to measure medication adherence and patterns of use. Information on the performance of monitors in a randomized controlled trial allows researchers and clinicians to unde... Read More about Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial.

A neural network approach to predicting price negotiation outcomes in business-to-business contexts (2012)
Journal Article
Moosmayer, D. C., Chong, A. Y. L., Liu, M. J., & Schuppar, B. (2013). A neural network approach to predicting price negotiation outcomes in business-to-business contexts. Expert Systems with Applications, 40(8), https://doi.org/10.1016/j.eswa.2012.12.018

Price premiums are a key profit driver for long-term business relationships. For sellers in business-to-business (B2B) relationships, it is important to have appropriate strategies to negotiate price increases without trading off the relationships wi... Read More about A neural network approach to predicting price negotiation outcomes in business-to-business contexts.

Soft-bound synaptic plasticity increases storage capacity (2012)
Journal Article
van Rossum, M. C., Shippi, M., & Barrett, A. B. (2012). Soft-bound synaptic plasticity increases storage capacity. PLoS Computational Biology, 8(12), Article e1002836. https://doi.org/10.1371/journal.pcbi.1002836

Accurate models of synaptic plasticity are essential to understand the adaptive properties of the nervous system and for realistic models of learning and memory. Experiments have shown that synaptic plasticity depends not only on pre- and post-synapt... Read More about Soft-bound synaptic plasticity increases storage capacity.

What do we mean by wet? Geoarchaeology and the reconstruction of water availability (2012)
Journal Article
Jones, M. D. (2013). What do we mean by wet? Geoarchaeology and the reconstruction of water availability. Quaternary International, 308-309, 76-79. https://doi.org/10.1016/j.quaint.2012.12.015

Geoarchaeology has a key role to play in the human-climate-environment debate, including research into the controls and variability of water availability. However its interdisciplinarity can cause complications as well as advantages and leads to conf... Read More about What do we mean by wet? Geoarchaeology and the reconstruction of water availability.

Can GPs working in secure environments in England re-license using the Royal College of General Practitioners revalidation proposals? (2012)
Journal Article
Coomber, J., Charlton, R., Thistlethwaite, J. E., & England, L. (2012). Can GPs working in secure environments in England re-license using the Royal College of General Practitioners revalidation proposals?. BMC Family Practice, 13(123), https://doi.org/10.1186/1471-2296-13-123

Background Revalidation for UK doctors is expected to be introduced from late 2012. For general practitioners (GPs), this entails collecting supporting information to be submitted and assessed in a revalidation portfolio every five years. The aim of... Read More about Can GPs working in secure environments in England re-license using the Royal College of General Practitioners revalidation proposals?.

Medieval business networks: St Mary's guild and the borough court in later medieval Nottingham (2012)
Journal Article
Goddard, R. (2013). Medieval business networks: St Mary's guild and the borough court in later medieval Nottingham. Urban History, 40(1), 3-27. https://doi.org/10.1017/s0963926812000600

Historians have suggested that medieval urban guilds played a role in political and commercial networking. Guilds' commercial protectionism was designed to benefit their membership and close ties have been discovered between merchant guilds and urban... Read More about Medieval business networks: St Mary's guild and the borough court in later medieval Nottingham.

The visualised foetus: A cultural and political analysis of ultrasound imagery (2012)
Book
Roberts, J. (2012). The visualised foetus: A cultural and political analysis of ultrasound imagery. Routledge. https://doi.org/10.4324/9781315551746

© 2012 Julie Roberts. All rights reserved. The latest three- and four dimensional images produced by modern ultrasound technology offer strikingly realistic representations of the foetus - representations that have further transformed experiences of... Read More about The visualised foetus: A cultural and political analysis of ultrasound imagery.

Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition (2012)
Journal Article
Smith, S. J., Wilson, M., Ward, J. H., Rahman, C. V., Peet, A. C., Macarthur, D. C., …Rahman, R. (2012). Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition. PLoS ONE, 7(12), Article e52335. https://doi.org/10.1371/journal.pone.0052335

INTRODUCTION Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted agents. We present comprehensive characterization of tumor aggregates generated... Read More about Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition.

Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study (2012)
Journal Article
Garrud, P., & Yates, J. (2012). Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study. BMC Medical Education, 12(Decemb), Article 8. https://doi.org/10.1186/1472-6920-12-124

Background 10-15% of students struggle at some point in their medicine course. Risk factors include weaker academic qualifications, male gender, mental illness, UK ethnic minority status, and poor study skills. Recent research on an undergraduate... Read More about Profiling strugglers in a graduate-entry medicine course at Nottingham: a retrospective case study.

The cosmology of the Fab-Four (2012)
Journal Article
Copeland, E. J., Padilla, A., & Saffin, P. M. (2012). The cosmology of the Fab-Four. Journal of Cosmology and Astroparticle Physics, 2012(12), Article 026. https://doi.org/10.1088/1475-7516/2012/12/026

We have recently proposed a novel self tuning mechanism to alleviate the famous cosmological constant problem, based on the general scalar tensor theory proposed by Horndeski. The self-tuning model ends up consisting of four geometric terms in the ac... Read More about The cosmology of the Fab-Four.

Click chemistry in carbon nanoreactors (2012)
Journal Article
Rance, G. A., Solomonsz, W. A., & Khobystov, A. N. (2013). Click chemistry in carbon nanoreactors. Chemical Communications, 49(11), https://doi.org/10.1039/C2CC38035H

Copper-nanoparticle catalytic centres anchored at the 5 graphitic step-edges within hollow carbon nanoreactors exhibit superior activity and stability in cycloaddition reactions as compared to catalytic centres outside the nanoreactors. Nanoscale con... Read More about Click chemistry in carbon nanoreactors.

Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator (2012)
Journal Article
Mobasheri, A. (2012). Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator. Frontiers in Endocrinology, 3(153), Article 153. https://doi.org/10.3389/fendo.2012.00153

In the skeletal system glucose serves as an essential source of energy for the development, growth, and maintenance of bone and articular cartilage. It is particularly needed for skeletal morphogenesis during embryonic growth and fetal development. G... Read More about Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator.

An innovative psychometric solar-powered water desalination system (2012)
Journal Article
Shatat, M., Riffat, S., & Gan, G. (2016). An innovative psychometric solar-powered water desalination system. International Journal of Low-Carbon Technologies, 11(2), https://doi.org/10.1093/ijlct/cts075

Important advances have been made in solar water desalination technology but their wide application is restricted by relatively high capital and running costs. Until recently, solar concentrator collectors had usually been employed to distill water i... Read More about An innovative psychometric solar-powered water desalination system.

A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium (2012)
Journal Article
Safuan, S., Storr, S. J., Patel, P. M., & Martin, S. G. (2012). A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium. Lymphatic Research and Biology, 10(4), https://doi.org/10.1089/lrb.2012.0007

Background: Lymphovascular invasion (LVI) is an important step in the metastatic cascade; tumor cell migration and adhesion to blood and lymphatic vessels is followed by invasion through the vessel wall and subsequent systemic spread. Although prim... Read More about A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium.

Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage (2012)
Journal Article
Gunning, S. J., Chung, K. K., Donaldson, P. J., & Webb, K. F. (2012). Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage. American Journal of Physiology - Cell Physiology, 303(12), C1252-C1259. https://doi.org/10.1152/ajpcell.00237.2012

The initiation of lens cataract has long been associated with the development of a membrane "leak" in lens fiber cells that depolarizes the lens intracellular potential and elevates intracellular Na+ and Ca2+ concentrations. It has been proposed that... Read More about Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage.

The “Sharp” blade against HIF-mediated metastasis (2012)
Journal Article
Amelio, I., & Melino, G. (2012). The “Sharp” blade against HIF-mediated metastasis. Cell Cycle, 11(24), 4530-4535. https://doi.org/10.4161/cc.22820

Hypoxia-inducible factors (HIFs) control cellular adaptation to oxygen deprivation. Cancer cells engage HIFs to sustain their growth in adverse conditions, thus promoting a cellular reprograming that includes metabolism, proliferation, survival and m... Read More about The “Sharp” blade against HIF-mediated metastasis.

The placental renin-angiotensin system and oxidative stress in pre-eclampsia (2012)
Journal Article
Mistry, H., Kurlak, L., & Broughton Pipkin, F. (2013). The placental renin-angiotensin system and oxidative stress in pre-eclampsia. Placenta, 34(2), https://doi.org/10.1016/j.placenta.2012.11.027

There is an inverse correlation between human birthweight and umbilical venous angiotensin II (AngII) concentrations. Oxidative stress and increased pro-renin receptor (PRR) both enhance the cleavage of angiotensin I from angiotensinogen (AGT). Pre-e... Read More about The placental renin-angiotensin system and oxidative stress in pre-eclampsia.