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Coordinate based random effect size meta-analysis of neuroimaging studies (2017)
Journal Article
Tench, C. R., Tanasescu, R., Constantinescu, C. S., Auer, D. P., & Cottam, W. J. (in press). Coordinate based random effect size meta-analysis of neuroimaging studies. NeuroImage, 153, https://doi.org/10.1016/j.neuroimage.2017.04.002

Low power in neuroimaging studies can make them difficult to interpret, and Coordinate based meta-analysis (CBMA) may go some way to mitigating this issue. CBMA has been used in many analyses to detect where published functional MRI or voxel-based mo... Read More about Coordinate based random effect size meta-analysis of neuroimaging studies.

The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis (2017)
Journal Article
Morandi, E., Tanasescu, R., Tarlinton, R. E., Constantinescu, C. S., Zhang, W., Tench, C. R., & Gran, B. (2017). The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis. PLoS ONE, 12(2), Article e0172415. https://doi.org/10.1371/journal.pone.0172415

Background: The interaction between genetic and environmental factors is crucial to multiple sclerosis (MS) pathogenesis. Human Endogenous Retroviruses (HERVs) are endogenous viral elements of the human genome whose expression is associated with MS.... Read More about The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis.

Potential pitfalls when denoising resting state fMRI data using nuisance regression (2016)
Journal Article
Bright, M. G., Tench, C. R., & Murphy, K. (2017). Potential pitfalls when denoising resting state fMRI data using nuisance regression. NeuroImage, 154, 159-168. https://doi.org/10.1016/j.neuroimage.2016.12.027

In resting state fMRI, it is necessary to remove signal variance associated with noise sources, leaving cleaned fMRI time-series that more accurately reflect the underlying intrinsic brain fluctuations of interest. This is commonly achieved through n... Read More about Potential pitfalls when denoising resting state fMRI data using nuisance regression.

Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease (2016)
Journal Article
Meng, D., Hosseini, A. A., Simpson, R. J., Shaikh, Q., Tench, C. R., Dineen, R. A., & Auer, D. P. (2017). Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease. Radiology, 282(2), 502-515. https://doi.org/10.1148/radiol.2016152685

Purpose: To investigate associations between neuroimaging markers of cerebrovascular disease, including lesion topography and extent and severity of strategic and global cerebral tissue injury, and cognition in carotid artery disease (CAD). Material... Read More about Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease.

Imaging central veins in brain lesions with 3-T T2*-weighted magnetic resonance imaging differentiates multiple sclerosis from microangiopathic brain lesions (2016)
Journal Article
Mistry, N., Abdel-Fahim, R., Samaraweera, A., Mougin, O., Tallantyre, E., Tench, C., …Evangelou, N. (2016). Imaging central veins in brain lesions with 3-T T2*-weighted magnetic resonance imaging differentiates multiple sclerosis from microangiopathic brain lesions. Multiple Sclerosis Journal, 22(10), 1289-1296. https://doi.org/10.1177/1352458515616700

Functional reorganisation in chronic pain and neural correlates of pain sensitisation (2016)
Journal Article
Tanasescu, R., Cottam, W., Condon, L., Tench, C. R., & Auer, D. P. (2016). Functional reorganisation in chronic pain and neural correlates of pain sensitisation. Neuroscience and Biobehavioral Reviews, 68, 120-133. https://doi.org/10.1016/j.neubiorev.2016.04.001

© 2016 Published by Elsevier Ltd. Maladaptive mechanisms of pain processing in chronic pain conditions (CP) are poorly understood. We used coordinate based meta-analysis of 266 fMRI pain studies to study functional brain reorganisation in CP and expe... Read More about Functional reorganisation in chronic pain and neural correlates of pain sensitisation.

Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study (2015)
Journal Article
Manouchehrinia, A., Edwards, L. J., Roshanisefat, H., Tench, C. R., & Constantinescu, C. S. (2015). Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study. BMJ Open, 5(5), 1-7. https://doi.org/10.1136/bmjopen-2015-007806

Objective: To determine if comorbid asthma is associated with accumulation of multiple sclerosis (MS)-related impairment and disability. Method: We sent a comprehensive questionnaire to a cohort of patients with MS and examined the association bet... Read More about Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study.

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article
Tench, C. R., Tanasescu, R., Auer, D. P., & Constantinescu, C. S. (2013). Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics. PLoS ONE, 8(7), Article e70143. https://doi.org/10.1371/journal.pone.0070143

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More about Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics.