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Attitudes and current practice in alcohol screening, brief intervention, and referral for treatment among staff working in urgent and emergency settings: a survey (2023)
Presentation / Conference
Blake, H., Yildirim, M., Premakumar, V., Morris, L., Miller, P., & Coffey, F. (2023, June). Attitudes and current practice in alcohol screening, brief intervention, and referral for treatment among staff working in urgent and emergency settings: a survey. Presented at Tomorrow’s Doctors Conference 2023, London, UK

The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review (2023)
Journal Article
Khan, M., Cassidy, E., Parkin, T., Wallace, A., Carter, B., Paton, J., …Bunn, L. (2023). The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review. Cerebellum, https://doi.org/10.1007/s12311-023-01555-z

Ataxia telangiectasia (A-T) is a rare, multisystem progressive condition that typically presents in early childhood. In the absence of cure, people with A-T require coordinated multidisciplinary care to manage their complex array of needs and to mini... Read More about The Care and Management of Children and Young People with Ataxia Telangiectasia Provided by Nurses and Allied Health Professionals: a Scoping Review.

Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models (2023)
Journal Article
Liao, W., Coupland, C., Burchardt, J., Baldwin, D. R., Gleeson, F. V., Hippisley-Cox, J., & DART initiative. (2023). Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models. Lancet Respiratory Medicine, https://doi.org/10.1016/S2213-2600%2823%2900050-4

Background: Lung cancer is the second most common cancer in incidence and the leading cause of cancer deaths worldwide. Meanwhile, lung cancer screening with low-dose CT can reduce mortality. The UK National Screening Committee recommended targeted l... Read More about Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models.

How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study (2022)
Journal Article
Grunwald, I. Q., Wagner, V., Podlasek, A., Koduri, G., Guyler, P., Gerry, S., …Walter, S. (2022). How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study. Cost Effectiveness and Resource Allocation, 20(1), Article 59. https://doi.org/10.1186/s12962-022-00395-8

Background: There is level 1 evidence for cerebral thrombectomy with thrombolysis in acute large vessel occlusion. Many hospitals are now contemplating setting up this life-saving service. For the hospital, however, the first treatment is associated... Read More about How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study.

Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis (2022)
Journal Article
Subhani, M., Sheth, A., Ahmed, J., Wijayasiri, P., Gardezi, S. A., Enki, D., …Aravinthan, A. D. (2022). Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis. Thrombosis Research, 215, 19-29. https://doi.org/10.1016/j.thromres.2022.05.004

Background and Aims: Historically, bleeding was thought to be a frequent and fatal complication of liver disease. However, thrombosis due to coagulation disorders in cirrhosis remains a real risk. We aim to systematically analyse published articles t... Read More about Incidence and prevalence of venous thromboembolism in chronic liver disease: A systematic review and meta-analysis.

The natural history of ataxia-telangiectasia (A-T): A systematic review (2022)
Journal Article
Petley, E., Yule, A., Alexander, S., Ojha, S., & Whitehouse, W. P. (2022). The natural history of ataxia-telangiectasia (A-T): A systematic review. PLoS ONE, 17(3), Article e0264177. https://doi.org/10.1371/journal.pone.0264177

Background: Ataxia-telangiectasia is an autosomal recessive, multi-system, and life-shortening disease caused by mutations in the ataxia-telangiectasia mutated gene. Although widely reported, there are no studies that give a comprehensive picture of... Read More about The natural history of ataxia-telangiectasia (A-T): A systematic review.

Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice (2022)
Journal Article
Tadavarthi, Y., Makeeva, V., Wagstaff, W., Zhan, H., Podlasek, A., Bhatia, N., …Trivedi, H. (2022). Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice. Radiology: Artificial Intelligence, 4(2), Article e210114. https://doi.org/10.1148/ryai.210114

Artificial intelligence has become a ubiquitous term in radiology over the past several years, and much attention has been given to applications that aid radiologists in the detection of abnormalities and diagnosis of diseases. However, there are man... Read More about Overview of Noninterpretive Artificial Intelligence Models for Safety, Quality, Workflow, and Education Applications in Radiology Practice.

Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content (2022)
Journal Article
Taylor, M., Simoes, F., Smith, J., Genapathy, S., Canning, A., Lledos, M., …Zelzer, M. (2022). Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content. Surface and Interface Analysis, 54(4), 417-432. https://doi.org/10.1002/sia.7052

Peptide-coated surfaces are widely employed in biomaterial design, but quantifiable correlation between surface composition and biological response is challenging due to, for example, instrumental limitations, a lack of suitable model surfaces or lim... Read More about Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.

“I don’t want to take buprenorphine for the rest of my life”: Acceptance and Commitment Therapy for a Client Struggling to Reduce Low-Dose Buprenorphine (a Hermeneutic Single-Case Efficacy Design) (2021)
Journal Article
Shepherd, K., Pritty, B., Tickle, A., & Moghaddam, N. (2023). “I don’t want to take buprenorphine for the rest of my life”: Acceptance and Commitment Therapy for a Client Struggling to Reduce Low-Dose Buprenorphine (a Hermeneutic Single-Case Efficacy Design). International Journal of Mental Health and Addiction, 21(4), 2418-2441. https://doi.org/10.1007/s11469-021-00729-2

The misuse of substances is often maintained by both physical and psychological factors. Opioid-substitution medications manage physical aspects of addiction; however, difficulties with emotional regulation and avoidance perpetuate continued substanc... Read More about “I don’t want to take buprenorphine for the rest of my life”: Acceptance and Commitment Therapy for a Client Struggling to Reduce Low-Dose Buprenorphine (a Hermeneutic Single-Case Efficacy Design).

Sox-positive cell population in the adult cerebellum increases upon tissue degeneration (2021)
Journal Article
Salih, S., Nizamudeen, Z. A., De Melo, N., Chakrabarti, L., & Sottile, V. (2022). Sox-positive cell population in the adult cerebellum increases upon tissue degeneration. Experimental Neurology, 348, Article 113950. https://doi.org/10.1016/j.expneurol.2021.113950

Adult neurogenesis is well-described in the subventricular and subgranular zones of the mammalian brain. Recent observations that resident glia express stem cell markers in some areas of the brain not traditionally associated with neurogenesis hint t... Read More about Sox-positive cell population in the adult cerebellum increases upon tissue degeneration.

Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review (2021)
Journal Article
Ting, D. S. J., Gopal, B. P., Deshmukh, R., Seitzman, G. D., Said, D. G., & Dua, H. S. (2022). Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review. Ocular Surface, 23, 27-39. https://doi.org/10.1016/j.jtos.2021.11.003

Infectious keratitis (IK) represents the leading cause of corneal blindness worldwide, particularly in developing countries. A good outcome of IK is contingent upon timely and accurate diagnosis followed by appropriate interventions. Currently, IK is... Read More about Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review.

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA (2021)
Journal Article
Wang, Y., Meng, X., Wang, A., Xie, X., Pan, Y., Johnston, S. C., …CHANCE-2 Investigators. (2021). Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA. New England Journal of Medicine, 385(27), 2520-2530. https://doi.org/10.1056/NEJMoa2111749

BACKGROUND Comparisons between ticagrelor and clopidogrel for the secondary prevention of stroke in CYP2C19 loss-of-function carriers have not been extensively performed. METHODS We conducted a randomized, double-blind, placebo-controlled trial at 20... Read More about Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA.

Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination (2021)
Journal Article
Allen, C. M., Ramsamy, S., Tarr, A. W., Tighe, P. J., Irving, W. L., Tanasescu, R., & Evans, J. R. (2021). Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination. Annals of Neurology, 90(2), 315-318. https://doi.org/10.1002/ana.26144

Although SARS-CoV-2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain–Barré syndrome (GBS) occurring within 3 weeks of vaccination with the Oxford–AstraZeneca SARS-CoV-2 vaccine. This rare neurol... Read More about Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination.

A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial (2021)
Journal Article
Shaw, D., Martin, M. J., Sutherland, L., Shaw, K., Parrish, C., Singleton, N., …Harrison, T. (2021). A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial. Respirology, 26(7), 666-672. https://doi.org/10.1111/resp.14055

Background and objective: Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker that reflects IL-4/IL-13 production and therefore represents T2 allergic inflammation. FeNO has previously been used to guide inhaled corticosteroid (ICS) tr... Read More about A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial.

Opioid prescription at postoperative discharge: a retrospective observational cohort study (2021)
Journal Article
Daliya, P., Adiamah, A., Roslan, F., Theophilidou, E., Knaggs, R., Levy, N., & Lobo, D. (2021). Opioid prescription at postoperative discharge: a retrospective observational cohort study. Anaesthesia, 76(10), 1367-1376. https://doi.org/10.1111/anae.15460

Opioid misuse is now considered a major public health epidemic in North America, with substantial social and financial consequences. As well as socio-economic and commercial drivers, modifiable risk-factors that have resulted in this crisis have been... Read More about Opioid prescription at postoperative discharge: a retrospective observational cohort study.

A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series (2021)
Journal Article
Reeve, A., Moghaddam, N., Tickle, A., & Young, D. (2021). A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series. Clinical Psychology and Psychotherapy, 28(5), 1001-1019. https://doi.org/10.1002/cpp.2555

Purpose Recent intervention research for burnout amongst those working in health and social care contexts has found acceptance and commitment therapy (ACT) interventions to be of use but has provided less clarity on the role of psychological flexibi... Read More about A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series.

Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery (2021)
Journal Article
Lizio, M. G., Liao, Z., Shipp, D. W., Boitor, R., Mihai, R., Sharp, J. S., …Notingher, I. (2021). Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery. Biomedical Optics Express, 12(2), 940-954. https://doi.org/10.1364/boe.411648

The standard treatment for breast cancer is surgical removal mainly through breast conserving surgey (BCS). We developed a new technique based on auto-fluorescence (AF) spectral imaging and Raman spectroscopy for fast intraoperative assessment of exc... Read More about Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery.