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Incidence, prevalence and survival in patients with Langerhans cell histiocytosis: A national registry study from England, 2013–2019 (2022)
Journal Article
Liu, H., Stiller, C. A., Crooks, C. J., Rous, B., Bythell, M., Broggio, J., …West, J. (2022). Incidence, prevalence and survival in patients with Langerhans cell histiocytosis: A national registry study from England, 2013–2019. British Journal of Haematology, 199(5), 728-738. https://doi.org/10.1111/bjh.18459

This analysis is the largest population-based study to date to provide contemporary and comprehensive epidemiological estimates of all third edition of the International Classification of Diseases for Oncology (ICD-O-3) coded Langerhans cell histiocy... Read More about Incidence, prevalence and survival in patients with Langerhans cell histiocytosis: A national registry study from England, 2013–2019.

Prehabilitation and Rehabilitation for Patients with Lung Cancer: A Review of Where we are Today (2022)
Journal Article
Burnett, C., Bestall, J. C., Burke, S., Morgan, E., Murray, R. L., Greenwood-Wilson, S., …Franks, K. N. (2022). Prehabilitation and Rehabilitation for Patients with Lung Cancer: A Review of Where we are Today. Clinical Oncology, 34(11), 724-732. https://doi.org/10.1016/j.clon.2022.08.028

Lung cancer is the third most common type of cancer in the UK, with nearly 50 000 new cases diagnosed a year. Treatments for lung cancer have improved in recent years with the advent of new surgical and radiotherapy techniques and the increased use o... Read More about Prehabilitation and Rehabilitation for Patients with Lung Cancer: A Review of Where we are Today.

Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units. QJM: An International Journal of Medicine, 116(1), 63-67. https://doi.org/10.1093/qjmed/hcac218

Summary Background Pulse oximeters are widely used to monitor blood oxygen saturations, although concerns exist that they are less accurate in individuals with pigmented skin. Aims This study aimed to determine if patients with pigmented skin were mo... Read More about Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units.

Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores (2022)
Journal Article
Forster, S., McKeever, T. M., Churpek, M., Gonem, S., & Shaw, D. (2022). Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores. Clinical Medicine, 22(5), 409-415. https://doi.org/10.7861/clinmed.2022-0074

Aims Accurately predicting risk of patient deterioration is vital. Altered physiology in chronic disease affects the prognostic ability of vital signs based early warning score systems. We aimed to assess the potential of early warning score patterns... Read More about Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores.

Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic (2022)
Journal Article
Fuller, A., Hancox, J., Vedhara, K., Card, T., Mallen, C., Van-Tam, J. S. N., & Abhishek, A. (2022). Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic. PLoS ONE, 17(9), Article e0267769. https://doi.org/10.1371/journal.pone.0267769

Objectives To explore barriers and facilitators to COVID-19, influenza, and pneumococcal vaccine uptake in immunosuppressed adults with immune-mediated inflammatory diseases (IMIDs). Methods Recruiting through national patient charities and a local h... Read More about Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic.

Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv) (2022)
Journal Article
Martello, E., Gillingham, E. L., Phalkey, R., Vardavas, C., Nikitara, K., Bakonyi, T., …Leonardi-Bee, J. (2022). Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv). Ticks and Tick-borne Diseases, 13(6), Article 102028. https://doi.org/10.1016/j.ttbdis.2022.102028

Tick-borne encephalitis (TBE) is an infection caused by the Tick-borne encephalitis virus (TBEv) and it is common in Europe. The virus is predominantly transmitted by ticks, but other non-vectorial modes of transmission are possible. This systematic... Read More about Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv).

Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions (2022)
Journal Article
Geetha, D., Kronbichler, A., Rutter, M., Bajpai, D., Menez, S., Weissenbacher, A., …Luyckx, V. (2022). Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions. Nature Reviews Nephrology, https://doi.org/10.1038/s41581-022-00618-4

The coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected patients with kidney disease, causing significant challenges in disease management, kidney research and trainee education. For patients, increased infection risk and dis... Read More about Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions.

The epidemiology of diphtheria in Haiti, December 2014-June 2021: A spatial modeling analysis (2022)
Journal Article
Ikejezie, J., Langley, T., Lewis, S., Bisanzio, D., & Phalkey, R. (2022). The epidemiology of diphtheria in Haiti, December 2014-June 2021: A spatial modeling analysis. PLoS ONE, 17(8), Article e0273398. https://doi.org/10.1371/journal.pone.0273398

BACKGROUND: Haiti has been experiencing a resurgence of diphtheria since December 2014. Little is known about the factors contributing to the spread and persistence of the disease in the country. Geographic information systems (GIS) and spatial analy... Read More about The epidemiology of diphtheria in Haiti, December 2014-June 2021: A spatial modeling analysis.

Mental health systems in six Caribbean small island developing states: a comparative situational analysis (2022)
Journal Article
Walker, I. F., Asher, L., Pari, A., Attride-Stirling, J., Oyinloye, A. O., Simmons, C., …Gibson, R. C. (2022). Mental health systems in six Caribbean small island developing states: a comparative situational analysis. International Journal of Mental Health Systems, 16, Article 39. https://doi.org/10.1186/s13033-022-00552-9

Background: Small island developing states (SIDS) have particular mental health system needs due to their remoteness and narrow resource base. We conducted situational analyses to support mental health system strengthening in six SIDS: Anguilla, Berm... Read More about Mental health systems in six Caribbean small island developing states: a comparative situational analysis.

Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout (2022)
Journal Article
Cipolletta, E., Tata, L. J., Nakafero, G., Avery, A. J., Mamas, M. A., & Abhishek, A. (2022). Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout. Journal of the American Medical Association, 328(5), 440-450. https://doi.org/10.1001/jama.2022.11390

Importance: Gout is associated with cardiovascular diseases. The temporal association between gout flares and cardiovascular events has not been investigated. Objective: To investigate whether there is a transient increase in risk of cardiovascular e... Read More about Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout.

Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman (2022)
Journal Article
Alsumri, H., Fiaschi, L., Gibson, J., Bains, M., & Szatkowski, L. (2022). Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman. Journal of Health and Medical Informatics, 13, Article 54

Objectives: To examine the association between PCOS and selected metabolic, pregnancy and neonatal outcomes among pregnant women and their newborns. Methods: Cohort study using electronic hospital records from two tertiary hospitals in Oman. Data wer... Read More about Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman.

Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (2022)
Journal Article
Crooks, C. J., West, J., Fogarty, A., Morling, J. R., Grainge, M. J., Gonem, S., …Card, T. R. (2022). Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2. American Journal of Epidemiology, 191(11), 1944-1953. https://doi.org/10.1093/aje/kwac126

We compared the performance of prognostic tools for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using parameters fitted either at the time of hospital admission or across all time points of an admission. This cohort study used clinic... Read More about Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2.

The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy (2022)
Journal Article
Lewis-Lloyd, C. A., Humes, D. J., West, J., Peacock, O., & Crooks, C. J. (2022). The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy. Annals of Surgery, 276(3), E177-E184. https://doi.org/10.1097/SLA.0000000000005563

Objective: To assess the impact of current guidelines by reporting weekly postoperative postdischarge venous thromboembolism (VTE) rates. Summary Background Data: Disparity exists between the postoperative thromboprophylaxis duration colectomy patien... Read More about The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy.

Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: Results from a genome-wide case-control study (2022)
Journal Article
Buch, S., Innes, H., Lutz, P. L., Nischalke, H. D., Marquardt, J. U., Fischer, J., …Stickel, F. (2022). Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: Results from a genome-wide case-control study. Gut, https://doi.org/10.1136/gutjnl-2022-327196

Objective: Hepatocellular carcinoma (HCC) often develops in patients with alcohol-related cirrhosis at an annual risk of up to 2.5%. Some host genetic risk factors have been identified but do not account for the majority of the variance in occurrence... Read More about Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: Results from a genome-wide case-control study.

Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study (2022)
Journal Article
Carter, N., Li, J., Xu, M., Li, L., Fan, X., Zhu, S., …Chattopadhyay, K. (2022). Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study. Endocrinology, Diabetes and Metabolism, 5(5), Article e353. https://doi.org/10.1002/edm2.353

Introduction: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health-related quality of life (HRQoL) of those who develop the disease. Context-specific assessment of HRQoL and its associated factors informs... Read More about Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study.

Participation in community-based lung cancer screening: the Yorkshire Lung Screening Trial (2022)
Journal Article
Crosbie, P. A., Gabe, R., Simmonds, I., Hancock, N., Alexandris, P., Kennedy, M., …Callister, M. E. J. (2022). Participation in community-based lung cancer screening: the Yorkshire Lung Screening Trial. European Respiratory Journal, 60(5), https://doi.org/10.1183/13993003.00483-2022

Background Screening with low-dose computed tomography (LDCT) reduces lung cancer mortality; however, the most effective strategy for optimising participation is unknown. Here we present data from the Yorkshire Lung Screening Trial, including respons... Read More about Participation in community-based lung cancer screening: the Yorkshire Lung Screening Trial.

Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink (2022)
Journal Article
Abhishek, A., Cipolletta, E., Nakafero, G., Avery, A. J., Mamas, M., & Tata, L. J. (2022). Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 81(12), https://doi.org/10.1136/ard-2022-222668

Exploring the influence of health management processes on health outcomes among internally displaced persons (IDPs) (2022)
Journal Article
Ekezie, W., Siebert, P., Timmons, S., Murray, R. L., & Bains, M. (2022). Exploring the influence of health management processes on health outcomes among internally displaced persons (IDPs). Journal of Migration and Health, 6, Article 100124. https://doi.org/10.1016/j.jmh.2022.100124

Background: Despite global action and policy initiatives, internally displaced persons (IDPs) experience poor living conditions and lack healthcare access compared to refugees. This study sought to understand the relationship between health managemen... Read More about Exploring the influence of health management processes on health outcomes among internally displaced persons (IDPs).

Opportunistic Non-Governmental Organisation Delivery of a Virtual Stop Smoking Service in England during the COVID-19 Lockdown (2022)
Journal Article
Davies, N. P., Callister, M. E., Copeland, H., Griffiths, S., Holtam, L., Lambert, P., …Murray, R. L. (2022). Opportunistic Non-Governmental Organisation Delivery of a Virtual Stop Smoking Service in England during the COVID-19 Lockdown. International Journal of Environmental Research and Public Health, 19(13), Article 7722. https://doi.org/10.3390/ijerph19137722

Smoking cessation services have rapidly transformed during the COVID-19 pandemic. Changes include pivoting from face-to-face to telephone and video call support, remote provision of stop smoking aids and more flexible appointments. This study reports... Read More about Opportunistic Non-Governmental Organisation Delivery of a Virtual Stop Smoking Service in England during the COVID-19 Lockdown.