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All Outputs (1362)

Use of radiography in small animal practice in the UK and Republic of Ireland in 2013 (2018)
Journal Article
Booth, N. J., Morley, S. J., & Ewers, R. (in press). Use of radiography in small animal practice in the UK and Republic of Ireland in 2013. Veterinary Record, 182(8), https://doi.org/10.1136/vr.104670

Background: Radiography is an essential diagnostic tool in small animal practice. A major transition is currently underway from film-screen to digital systems. However, there is limited published research detailing the use of radiography in practices... Read More about Use of radiography in small animal practice in the UK and Republic of Ireland in 2013.

Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach (2018)
Journal Article
Viljanto, M., Hillyer, L., Hincks, P., Pearce, C., & Paine, S. (2018). Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach. Journal of Veterinary Pharmacology and Therapeutics, 41(3), 469-475. https://doi.org/10.1111/jvp.12491

Medication and doping control has been established in horseracing to ensure the integrity of the sport and the welfare of the horses. This ensures that horses do not compete under the influence of any drugs, including omeprazole, a therapeutic medica... Read More about Re-evaluation of the regulation of omeprazole in racehorses: an evidence-based approach.

Identification of stable reference genes for quantitative PCR in koalas (2018)
Journal Article
Sarker, N., Fabijan, J., Emes, R. D., Hemmatzadeh, F., Meers, J., Moreton, J., …Tarlinton, R. E. (in press). Identification of stable reference genes for quantitative PCR in koalas. Scientific Reports, 8, Article 3364. https://doi.org/10.1038/s41598-018-21723-0

To better understand host and immune response to diseases, gene expression studies require identification of reference genes with stable expression for accurate normalisation. This study describes the identification and testing of reference genes wit... Read More about Identification of stable reference genes for quantitative PCR in koalas.

Science, culture, and care in laboratory animal research: interdisciplinary perspectives on the history and future of the 3Rs (2018)
Journal Article
Davies, G., Greenhough, B. J., Hobson-West, P., & Kirk, R. G. (in press). Science, culture, and care in laboratory animal research: interdisciplinary perspectives on the history and future of the 3Rs. Science, Technology, and Human Values, 43(4), https://doi.org/10.1177/0162243918757034

The principles of the 3Rs—replacement, refinement, and reduction—strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience. This special issue looks back to the origins... Read More about Science, culture, and care in laboratory animal research: interdisciplinary perspectives on the history and future of the 3Rs.

“I always feel like I have to rush…”: pet owner and small animal veterinary surgeons’ reflections on time during preventative healthcare consultations in the United Kingdom (2018)
Journal Article
Belshaw, Z., Robinson, N., Dean, R. S., & Brennan, M. L. (2018). “I always feel like I have to rush…”: pet owner and small animal veterinary surgeons’ reflections on time during preventative healthcare consultations in the United Kingdom. Veterinary Sciences, 5(1), Article 20. https://doi.org/10.3390/vetsci5010020

Canine and feline preventative healthcare consultations can be more complex than other consultation types, but they are typically not allocated additional time in the United Kingdom (UK). Impacts of the perceived length of UK preventative healthcare... Read More about “I always feel like I have to rush…”: pet owner and small animal veterinary surgeons’ reflections on time during preventative healthcare consultations in the United Kingdom.

Evaluation of sampling frequency, window size and sensor position for classification of sheep behaviour (2018)
Journal Article
Walton, E., Casey, C., Mitsch, J., Vázquez-Diosdado, J. A., Yan, J., Dottorini, T., …Kaler, J. (2018). Evaluation of sampling frequency, window size and sensor position for classification of sheep behaviour. Royal Society Open Science, 5(2), https://doi.org/10.1098/rsos.171442

Automated behavioural classification and identification through sensors has the potential to improve health and welfare of the animals. Position of a sensor, sampling frequency and window size of segmented signal data has a major impact on classifica... Read More about Evaluation of sampling frequency, window size and sensor position for classification of sheep behaviour.

Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro (2018)
Journal Article
Nizamudeen, Z. A., Chakrabarti, L., & Sottile, V. (2018). Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro. Stem Cell Research, 28, 75-86. https://doi.org/10.1016/j.scr.2018.02.001

Fasudil is a clinically approved Rho-associated protein kinase (ROCK) inhibitor that has been used widely to treat cerebral consequences of subarachnoid haemorrhage. It is known to have a positive effect on animal models of neurological disorders inc... Read More about Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro.

Pulmonary basaloid squamous cell carcinoma in a dog (2018)
Journal Article
Morey-Matamalas, A., de Stefani, A., Corbetta, D., Grau-Roma, L., & de Brot, S. (2018). Pulmonary basaloid squamous cell carcinoma in a dog. Journal of Comparative Pathology, 159, https://doi.org/10.1016/j.jcpa.2017.12.007

A 9-year-old neutered male crossbred dog with a 4-week history of progressive vestibulocerebellar signs was presented for necropsy examination. Gross examination revealed neoplastic growth in the lungs, thoracic lymph nodes, the left kidney and the c... Read More about Pulmonary basaloid squamous cell carcinoma in a dog.

Zoonotic potential of Salmonella enterica carried by pet tortoises (2018)
Journal Article
Bruce, H. L., Barrow, P. A., & Rycroft, A. N. (2018). Zoonotic potential of Salmonella enterica carried by pet tortoises. Veterinary Record, 182(5), 141-141. https://doi.org/10.1136/vr.104457

The prevalence of Salmonella in chelonians is not known in the UK and it is not clear whether such Salmonella strains would be pathogenic for human beings. Some strains, such as members of the Arizonae subgroup, may be unable to cause anything more t... Read More about Zoonotic potential of Salmonella enterica carried by pet tortoises.

Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies (2018)
Journal Article
Wu, P., Farrell, W. E., Haworth, K. E., Emes, R. D., Kitchen, M. O., Glossop, J. R., …Fryer, A. A. (2018). Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies. Epigenetics, 13(2), 122-128. https://doi.org/10.1080/15592294.2016.1166321

Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450Karray analysis to dete... Read More about Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies.

Novel Entamoeba findings in nonhuman primates (2018)
Journal Article
Elsheikha, H. M., Regan, C. S., & Clark, C. G. (2018). Novel Entamoeba findings in nonhuman primates. Trends in Parasitology, 34(4), https://doi.org/10.1016/j.pt.2017.12.008

In addition to well-known human-infecting species, Entamoeba species not found in humans have been identified recently in nonhuman primates (NHPs). Importantly, it has become clear that the organism identified as Entamoeba histolytica in NHPs is usua... Read More about Novel Entamoeba findings in nonhuman primates.

True cowmen and commercial farmers: exploring vets’ and dairy farmers’ contrasting views of ‘good farming’ in relation to biosecurity (2018)
Journal Article
Shortall, O., Sutherland, L., Ruston, A., & Kaler, J. (in press). True cowmen and commercial farmers: exploring vets’ and dairy farmers’ contrasting views of ‘good farming’ in relation to biosecurity. Sociologia Ruralis, https://doi.org/10.1111/soru.12205

Responsibility for biosecurity in UK farming is being devolved from government to industry, with a greater emphasis on the veterinarian (vet)-farmer relationship. Although social science has shown that care for animals is part of ‘good farming’, the... Read More about True cowmen and commercial farmers: exploring vets’ and dairy farmers’ contrasting views of ‘good farming’ in relation to biosecurity.

Ultrasonographic-based predictive factors influencing successful return to racing after superficial digital flexor tendon injuries in flat racehorses: a retrospective cohort study in 469 Thoroughbred racehorses in Hong Kong (2018)
Journal Article
Alzola, R., Easter, C., Riggs, C., Gardner, D., & Freeman, S. (2018). Ultrasonographic-based predictive factors influencing successful return to racing after superficial digital flexor tendon injuries in flat racehorses: a retrospective cohort study in 469 Thoroughbred racehorses in Hong Kong. Equine Veterinary Journal, 50(5), 602-608. https://doi.org/10.1111/evj.12810

Background: Superficial digital flexor tendon (SDFT) injury is an important health and welfare concern in racehorses. It is generally diagnosed with ultrasonography, predictive ultrasonographic features have not been reported. Objectives: To determi... Read More about Ultrasonographic-based predictive factors influencing successful return to racing after superficial digital flexor tendon injuries in flat racehorses: a retrospective cohort study in 469 Thoroughbred racehorses in Hong Kong.

Owners and veterinary surgeons in the United Kingdom disagree about what should happen during a small animal vaccination consultation (2018)
Journal Article
Belshaw, Z., Robinson, N. J., Dean, R. S., & Brennan, M. L. (2018). Owners and veterinary surgeons in the United Kingdom disagree about what should happen during a small animal vaccination consultation. Veterinary Sciences, 5(1), https://doi.org/10.3390/vetsci5010007

Dog and cat vaccination consultations are a common part of small animal practice in the United Kingdom. Few data are available describing what happens during those consultations or what participants think about their content. The aim of this novel st... Read More about Owners and veterinary surgeons in the United Kingdom disagree about what should happen during a small animal vaccination consultation.

Quantitative outcomes of a One Health approach to study global health challenges (2018)
Journal Article
Falzon, L. C., Lechner, I., Chantziaras, I., Collineau, L., Courcoul, A., Filippitzi, M., …Brennan, M. L. (2018). Quantitative outcomes of a One Health approach to study global health challenges. EcoHealth, 15(1), 209-227. https://doi.org/10.1007/s10393-017-1310-5

Having gained momentum in the last decade, the One Health initiative promotes a holistic approach to address complex global health issues. Before recommending its adoption to stakeholders, however, it is paramount to first compile quantitative eviden... Read More about Quantitative outcomes of a One Health approach to study global health challenges.

Epidemiological survey of equine influenza in Andalusia, Spain (2018)
Journal Article
Jurado-Tarifa, E., Daly, J. M., Pérez-Écija, A., Barba-Recreo, M., Mendoza, F., Al-Shuwaikh, A., & García-Bocanegra, I. (2018). Epidemiological survey of equine influenza in Andalusia, Spain. Preventive Veterinary Medicine, 151, https://doi.org/10.1016/j.prevetmed.2018.01.003

Equine influenza is a highly contagious respiratory disease considered the most important respiratory disease in equids. Although influenza A virus (IAV) has caused outbreaks in equids worldwide, surveillance on these species in Spain has not been co... Read More about Epidemiological survey of equine influenza in Andalusia, Spain.

HumanMethylation450K array–identified biomarkers predict tumour recurrence/progression at initial diagnosis of high-risk non-muscle Invasive bladder cancer (2018)
Journal Article
Kitchen, M. O., Bryan, R. T., Emes, R. D., Luscombe, C. J., Cheng, K., Zeegers, M. P., …Fryer, A. A. (in press). HumanMethylation450K array–identified biomarkers predict tumour recurrence/progression at initial diagnosis of high-risk non-muscle Invasive bladder cancer. Biomarkers in Cancer,

Background: High-risk non-muscle invasive bladder cancer (HR-NMIBC) is a clinically unpredictable disease. Despite clinical risk estimation tools, many patients are undertreated with intra-vesical therapies alone, whereas others may be over-treated w... Read More about HumanMethylation450K array–identified biomarkers predict tumour recurrence/progression at initial diagnosis of high-risk non-muscle Invasive bladder cancer.

Use of clinical vignette questionnaires to investigate the variation in management of keratoconjunctivitis sicca and acute glaucoma in dogs (2018)
Journal Article
White, C., Downes, M. J., Jones, G., Wigfall, C., Dean, R. S., & Brennan, M. L. (2018). Use of clinical vignette questionnaires to investigate the variation in management of keratoconjunctivitis sicca and acute glaucoma in dogs. Veterinary Record, 182(1), https://doi.org/10.1136/vr.104390

There is little peer-reviewed research assessing therapeutic effectiveness in canine eye disease. Current treatments used in first opinion and ophthalmology referral practices are also somewhat poorly documented. The aim of this study was to investig... Read More about Use of clinical vignette questionnaires to investigate the variation in management of keratoconjunctivitis sicca and acute glaucoma in dogs.