All Outputs (63)

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma (2008)
Journal Article
Ridley, L., Rahman, R., Brundler, M., Ellison, D., Lowe, J., Robson, K., …Grundy, R. G. (2008). Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro-Oncology, 10(5), 675–689. https://doi.org/10.1215/15228517-2008-036

Telomeric 3?-overhang length is associated with the size of telomeres (2008)
Journal Article
Rahman, R., Forsyth, N. R., & Cui, W. (2008). Telomeric 3?-overhang length is associated with the size of telomeres. Experimental Gerontology, 43(4), 258-265. doi:10.1016/j.exger.2008.01.005

Telomeres are specialized DNA/protein complexes that cap eukaryotic chromosome ends as T-loop structures and maintain genomic integrity. Vertebrate telomeric DNA consists of tandem double-strand repeats which terminate in a 3 0 single-strand G-rich o... Read More about Telomeric 3?-overhang length is associated with the size of telomeres.

Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth (2006)
Journal Article
Rahman, R., Mo, L., & Cui, W. (2006). Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth. Biochemical and Biophysical Research Communications, 350(3), 796-802. doi:10.1016/j.bbrc.2006.09.125

Telomerase catalytic subunit (TERT) seems a key factor controlling telomerase activity, telomere length, and cell growth. To further address this issue, we forced expression of a catalytically inactive mutant human TERT (hTERT) in hTERT-immortalised... Read More about Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth.