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Design decisions and data completeness for experience sampling methods used in psychosis: systematic review (2022)
Journal Article
Deakin, E., Ng, F., Young, E., Thorpe, N., Newby, C., Coupland, C., …Slade, M. (2022). Design decisions and data completeness for experience sampling methods used in psychosis: systematic review. BMC Psychiatry, 22, Article 669. https://doi.org/10.1186/s12888-022-04319-x

Background: The experience sampling method (ESM) is an intensive longitudinal research method. Participants complete questionnaires at multiple times about their current or very recent state. The design of ESM studies is complex. People with psychosi... Read More about Design decisions and data completeness for experience sampling methods used in psychosis: systematic review.

European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction (2022)
Journal Article
Qureshi, N., Antoniou, S., Cornel, J. H., Schiele, F., Perrone-Filardi, P., Brachmann, J., …González-Juanatey, J. R. (2022). European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction. Advances in Therapy, https://doi.org/10.1007/s12325-022-02344-6

Introduction: The 2019 European Society of Cardiology and European Atherosclerosis Society (2019 ESC/EAS) guidelines stress the importance of managing low-density lipoprotein cholesterol (LDL-C) after myocardial infarction (MI) to reduce the risk of... Read More about European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction.

Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination (2022)
Journal Article
Gumber, L., Gomez, N., Hopkins, G., Tucis, D., Bartlett, L., Ayling, K., …Fairclough, L. (2023). Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination. Rheumatology, 62(6), 2294-2303. https://doi.org/10.1093/rheumatology/keac574

Objectives: COVID-19 vaccine responses in rare autoimmune rheumatic diseases (RAIRD) remain poorly understood, in particular there is little known about whether people develop effective T-cell responses. We conducted a prospective cohort study to eva... Read More about Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination.

Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. (2022)
Journal Article
Shoesmith, E., Huddlestone, L., Pervin, J., Shahab, L., Coventry, P., Coleman, T., …Ratschen, E. (2023). Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel. Nicotine & Tobacco Research, 25(4), 729-737. https://doi.org/10.1093/ntr/ntac242

Evidence suggests that smokers can successfully quit, remain abstinent or reduce smoking during a smokefree mental health inpatient stay, provided behavioural/pharmacological support are offered. However, few evidence-based strategies to prevent the... Read More about Promoting and maintaining changes in smoking behaviour for patients following discharge from a smokefree mental health inpatient stay: Development of a complex intervention using the Behaviour Change Wheel..

Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients (2022)
Journal Article
Mohammadnia, N., Akyea, R. K., Qureshi, N., Bax, W. A., & Cornel, J. H. (2022). Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients. European Heart Journal – Digital Health, 3(4), 578-586. https://doi.org/10.1093/ehjdh/ztac059

Aims: Familial hypercholesterolaemia (FH) is a disorder of LDL cholesterol clearance, resulting in increased risk of cardiovascular disease. Recently, we developed a Dutch Lipid Clinic Network (DLCN) criteria-based algorithm to facilitate FH detectio... Read More about Electronic health record-based facilitation of familial hypercholesterolaemia detection sensitivity of different algorithms in genetically confirmed patients.

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial (2022)
Journal Article
Mackenzie, I. S., Hawkey, C. J., Ford, I., Greenlaw, N., Pigazzani, F., Rogers, A., …MacDonald, T. M. (2022). Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400(10359), 1195-1205. https://doi.org/10.1016/S0140-6736%2822%2901657-9

Background: Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to determine whether allopurinol t... Read More about Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.

Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study (2022)
Journal Article
Law, M., Gasteiger, N., Vedhara, K., Massey, A., Jia, R., Ayling, K., …Broadbent, E. (2022). Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study. Psych, 4(4), 706-716. https://doi.org/10.3390/psych4040052

This longitudinal study investigated changes in and risk factors for anxiety and depression during the COVID-19 pandemic in a New Zealand cohort. Online surveys were distributed to 681 participants at three time-points: May 2020 (Time 1), August–Sept... Read More about Risk Factors and Changes in Depression and Anxiety over Time in New Zealand during COVID-19: A Longitudinal Cohort Study.

Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability (2022)
Journal Article
Laing, L., Salema, N., Jeffries, M., Shamsuddin, A., Sheikh, A., Chuter, A., …Keers, R. N. (2022). Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability. PLoS ONE, 17(10), Article e0275633. https://doi.org/10.1371/journal.pone.0275633

Introduction Medication errors are an important cause of morbidity and mortality. The pharmacist-led IT-based intervention to reduce clinically important medication errors (PINCER) intervention was shown to reduce medication errors when tested in a c... Read More about Understanding factors that could influence patient acceptability of the use of the PINCER intervention in primary care: A qualitative exploration using the Theoretical Framework of Acceptability.

Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme (2022)
Journal Article
Sheikh, A., Coleman, J., Chuter, A., Williams, R., Lilford, R., Slee, A., …Watson, N. (2022). Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme. Programme Grants for Applied Research, 10(7), 1-164. https://doi.org/10.3310/KSRS2009

Background: There is a need to identify approaches to reduce medication errors. Interest has converged on ePrescribing systems that incorporate computerised provider order entry and clinical decision support functionality. Objectives: We sought to de... Read More about Electronic prescribing systems in hospitals to improve medication safety: a multimethods research programme.

Understanding social care need through primary care big data: a rapid scoping review (2022)
Journal Article
Simpson, G., Kaluvu, L. M., Stokes, J., Roderick, P., Chapman, A., Akyea, R. K., …Dambha-Miller, H. (2022). Understanding social care need through primary care big data: a rapid scoping review. BJGP Open, 6(4), Article BJGPO.2022.0016. https://doi.org/10.3399/BJGPO.2022.0016

Background: A more comprehensive understanding and measurement of adult social care need could contribute to efforts to develop more effective, holistic personalised care, particularly for those with multiple long-term conditions (MLTC). Progress in... Read More about Understanding social care need through primary care big data: a rapid scoping review.

Understanding factors influencing uptake and sustainable use of the PINCER intervention at scale: A qualitative evaluation using Normalisation Process Theory (2022)
Journal Article
Laing, L., Salema, N. E., Jeffries, M., Shamsuddin, A., Sheikh, A., Chuter, A., …Keers, R. N. (2022). Understanding factors influencing uptake and sustainable use of the PINCER intervention at scale: A qualitative evaluation using Normalisation Process Theory. PLoS ONE, 17(9), Article e0274560. https://doi.org/10.1371/journal.pone.0274560

INTRODUCTION: Medication errors are an important cause of morbidity and mortality. The pharmacist-led IT-based intervention to reduce clinically important medication errors (PINCER) has demonstrated improvements in primary care medication safety, and... Read More about Understanding factors influencing uptake and sustainable use of the PINCER intervention at scale: A qualitative evaluation using Normalisation Process Theory.

Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic (2022)
Journal Article
Fuller, A., Hancox, J., Vedhara, K., Card, T., Mallen, C., Van-Tam, J. S. N., & Abhishek, A. (2022). Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic. PLoS ONE, 17(9), Article e0267769. https://doi.org/10.1371/journal.pone.0267769

Objectives To explore barriers and facilitators to COVID-19, influenza, and pneumococcal vaccine uptake in immunosuppressed adults with immune-mediated inflammatory diseases (IMIDs). Methods Recruiting through national patient charities and a local h... Read More about Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic.

P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention (2022)
Journal Article
Blackmore, C., Kendrick, D., & Orton, E. (2022). P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention. European Journal of Public Health, 32(Supplement_2), Article ckac095.061. https://doi.org/10.1093/eurpub/ckac095.061

Abstract Background Falls are a major cause of mortality and morbidity in older adults worldwide, yet those who are more physically active have a lower risk of falling. There is little information on which participants are most likely to complete fal... Read More about P04-07 Factors associated with maintenance of physical activity in older adults undertaking a strength and balance programme for falls prevention.

The frequency and nature of prescribing problems by GPs-in-training (REVISiT): a retrospective review (2022)
Journal Article
Salema, N. E., Bell, B., Marsden, K., Gookey, G., Swanwick, G., Bassi, M., …Knox, R. (2022). The frequency and nature of prescribing problems by GPs-in-training (REVISiT): a retrospective review. BJGP Open, 6(3), Article BJGPO.2021.0231. https://doi.org/10.3399/BJGPO.2021.0231

Background: Prescribing errors can cause significant morbidity and occur in about 5% of prescriptions in English general practices. Aim: To describe the frequency and nature of prescribing problems in a cohort of GPs-in-training to determine whether... Read More about The frequency and nature of prescribing problems by GPs-in-training (REVISiT): a retrospective review.

Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout (2022)
Journal Article
Cipolletta, E., Tata, L. J., Nakafero, G., Avery, A. J., Mamas, M. A., & Abhishek, A. (2022). Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout. Journal of the American Medical Association, 328(5), 440-450. https://doi.org/10.1001/jama.2022.11390

Importance: Gout is associated with cardiovascular diseases. The temporal association between gout flares and cardiovascular events has not been investigated. Objective: To investigate whether there is a transient increase in risk of cardiovascular e... Read More about Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout.

Cryptocurrency and new financial instruments: unquantified public health harms (2022)
Journal Article
Davies, N., & Ferris, S. (2022). Cryptocurrency and new financial instruments: unquantified public health harms. Lancet Public Health, 7(8), Article e655. https://doi.org/10.1016/S2468-2667%2822%2900173-6

Public health harms from gambling are now well recognised. Public Health England estimates societal gambling-related harm in England exceeds £1·27 billion. Australian research estimates that the years lost to disability from gambling exceeds that of... Read More about Cryptocurrency and new financial instruments: unquantified public health harms.

The effect of expressive writing on wound healing: Immunohistochemistry analysis of skin tissue two weeks after punch biopsy wounding (2022)
Journal Article
Robinson, H., Jarrett, P., Vedhara, K., Tarlton, J., Whiting, C., Law, M., & Broadbent, E. (2022). The effect of expressive writing on wound healing: Immunohistochemistry analysis of skin tissue two weeks after punch biopsy wounding. Journal of Psychosomatic Research, 161, Article 110987. https://doi.org/10.1016/j.jpsychores.2022.110987

Objective: To investigate the effects of expressive writing and its timing (pre or post wounding) on re-epithelialisation and leucocyte subsets within healing tissue. We previously showed expressive writing pre-wounding improved re-epithelialisation.... Read More about The effect of expressive writing on wound healing: Immunohistochemistry analysis of skin tissue two weeks after punch biopsy wounding.

Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study (2022)
Journal Article
Piernas, C., Patone, M., Astbury, N. M., Gao, M., Sheikh, A., Khunti, K., …Jebb, S. A. (2022). Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study. Lancet Diabetes and Endocrinology, 10(8), 571-580. https://doi.org/10.1016/s2213-8587%2822%2900158-9

Background: A high BMI has been associated with a reduced immune response to vaccination against influenza. We aimed to investigate the association between BMI and COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes a... Read More about Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study.

Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink (2022)
Journal Article
Abhishek, A., Cipolletta, E., Nakafero, G., Avery, A. J., Mamas, M., & Tata, L. J. (2022). Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 81(12), https://doi.org/10.1136/ard-2022-222668

Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study (2022)
Journal Article
Tan, P. S., Garriga, C., Clift, A., Liao, W., Patone, M., Coupland, C., …Hippisley-Cox, J. (2023). Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study. Gut, 72(3), 512-521. https://doi.org/10.1136/gutjnl-2021-326522

Objective Prior studies identified clinical factors associated with increased risk of pancreatic ductal adenocarcinoma (PDAC). However, little is known regarding their time-varying nature, which could inform earlier diagnosis. This study assessed tem... Read More about Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study.