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All Outputs (38)

A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia (2018)
Journal Article
Harwood, R. H., van der Wardt, V., Goldberg, S. E., Keamey, F., Logan, P., Hood-Moore, V., …Orrell, M. (2018). A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia. Pilot and Feasibility Studies, 4, Article 49. https://doi.org/10.1186/s40814-018-0239-y

Background: People with dementia progressively lose abilities and are prone to falling. Exercise- and activity-based interventions hold the prospect of increasing abilities, reducing falls, and slowing decline in cognition. Current falls prevention... Read More about A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia.

Withdrawal of antihypertensive therapy in people with dementia: feasibility study (2018)
Journal Article
van der Wardt, V., Burton, J. K., Conroy, S., Welsh, T., Logan, P., Taggar, J., …Gladman, J. (2018). Withdrawal of antihypertensive therapy in people with dementia: feasibility study. Pilot and Feasibility Studies, 4(1), Article 29. https://doi.org/10.1186/s40814-017-0221-0

© 2018 The Author(s). Background: This study explored the feasibility of a randomised controlled withdrawal trial of antihypertensive medication in normotensive people with dementia. Feasibility aspects included response, recruitment, exclusion and d... Read More about Withdrawal of antihypertensive therapy in people with dementia: feasibility study.

Attitudes of older people with mild dementia and mild cognitive impairment and their relatives about falls risk and prevention: a qualitative study (2017)
Journal Article
Peach, T., Pollock, K., van der Wardt, V., das Nair, R., Logan, P., & Harwood, R. H. (2017). Attitudes of older people with mild dementia and mild cognitive impairment and their relatives about falls risk and prevention: a qualitative study. PLoS ONE, 12(5), 1-15. https://doi.org/10.1371/journal.pone.0177530

Objective: To explore the perceptions of older people with mild dementia and mild cognitive impairment, and their family carers, about falling, falls risk and the acceptability of falls prevention interventions. Design: Qualitative study involving t... Read More about Attitudes of older people with mild dementia and mild cognitive impairment and their relatives about falls risk and prevention: a qualitative study.

Adherence support strategies for exercise interventions in people with mild cognitive impairment and dementia: a systematic review (2017)
Journal Article
van der Wardt, V., Hancox, J., Gondek, D., Logan, P., das Nair, R., Pollock, K., & Harwood, R. H. (2017). Adherence support strategies for exercise interventions in people with mild cognitive impairment and dementia: a systematic review. Preventive Medicine Reports, 7, https://doi.org/10.1016/j.pmedr.2017.05.007

Exercise-based therapy may improve health status for people with Mild Cognitive Impairment (MCI) or dementia but cannot work without adherence, which has proven difficult. This review aimed to evaluate strategies to support adherence among people wit... Read More about Adherence support strategies for exercise interventions in people with mild cognitive impairment and dementia: a systematic review.

Withdrawal of antihypertensive medication: a systematic review (2017)
Journal Article
van der Wardt, V., Harrison, J. K., Welsh, T. J., Conroy, S., & Gladman, J. R. (2017). Withdrawal of antihypertensive medication: a systematic review. Journal of Hypertension, 35, https://doi.org/10.1097/HJH.0000000000001405

Although antihypertensive medication is usually continued indefinitely, observations during wash-out phases in hypertension trials have shown that withdrawal of antihypertensive medication might be well tolerated to do in a considerable proportion of... Read More about Withdrawal of antihypertensive medication: a systematic review.

New horizons: the management of hypertension in people with dementia (2016)
Journal Article
Harrison, J. K., Van Der Wardt, V., Conroy, S. P., Stott, D. J., Dening, T., Gordon, A. L., …Gladman, J. R. (2016). New horizons: the management of hypertension in people with dementia. Age and Ageing, 45(6), 740-746. https://doi.org/10.1093/ageing/afw155

The optimal management of hypertension in people with dementia is uncertain. This review explores if people with dementia experience greater adverse effects from antihypertensive medications, if cognitive function is protected or worsened by controll... Read More about New horizons: the management of hypertension in people with dementia.

Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability (2016)
Journal Article
Conroy, S. P., Harrison, J. K., van der Wardt, V., Harwood, R. H., Logan, P., Welsh, T., & Gladman, J. R. (2016). Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability. Age and Ageing, 45(4), 456-462. https://doi.org/10.1093/ageing/afw050

BACKGROUND: Ambulatory blood pressure monitoring (ABPM) may be helpful for the management of hypertension, but little is known about its tolerability in people with dementia. OBJECTIVE: To review the published evidence to determine the tolerabil... Read More about Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability.

Should guidance for the use of antihypertensive medication in older people with frailty be different? (2015)
Journal Article
van der Wardt, V. (2015). Should guidance for the use of antihypertensive medication in older people with frailty be different?. Age and Ageing, 44(6), https://doi.org/10.1093/ageing/afv147

The benefits of antihypertensive treatments have been established in numerous large clinical trials. Although the Hypertension in the Very Elderly Trial (HYVET) confirmed the protective effect of blood pressure medication for healthy, older individua... Read More about Should guidance for the use of antihypertensive medication in older people with frailty be different?.

Recruitment of people with dementia in primary care –experiences from the HIND study (2015)
Journal Article
van der Wardt, V., Conroy, S., Tomas, W., Logan, P., Harrison, J. K., Taggar, J., & Gladman, J. R. (2015). Recruitment of people with dementia in primary care –experiences from the HIND study. European Geriatric Medicine, 6(Supp.1), S55-S56. https://doi.org/10.1016/S1878-7649%2815%2930191-1

OBJECTIVES: A purpose of the Hypertension in Dementia feasibility study was to explore recruitment of people with dementia and essential hypertension in primary care practices to prepare a withdrawal study of their antihypertensive medication. METH... Read More about Recruitment of people with dementia in primary care –experiences from the HIND study.

The Balance and the Mind study: baseline data (2015)
Journal Article
van der Wardt, V., Logan, P., Booth, V., Hood, V., Masud, T., & Harwood, R. H. (2015). The Balance and the Mind study: baseline data. European Geriatric Medicine, 6(1), Article S55. https://doi.org/10.1016/S1878-7649%2815%2930190-X

OBJECTIVES: The purpose of the study was to establish falls risk factors for people with mild cognitive impairment and mild dementia. METHODS: Survey of 76 people recruited from Memory Clinics (n=56), Falls Services (n=12), Community Geriatricians (... Read More about The Balance and the Mind study: baseline data.

The Association of Specific Executive Functions and Falls Risk in People with Mild Cognitive Impairment and Early-Stage Dementia (2015)
Journal Article
Harwood, R., Logan, P., van der Wardt, V., Logan, P. A., Hood, V., Booth, V., …Harwood, R. H. (2015). The Association of Specific Executive Functions and Falls Risk in People with Mild Cognitive Impairment and Early-Stage Dementia. Dementia and Geriatric Cognitive Disorders, 40(3-4), 178-185. https://doi.org/10.1159/000433523

Background/Aims: Impairment in executive function is associated with a heightened risk for falls in people with mild cognitive impairment (MCI) and dementia. The purpose of this study was to determine which aspects of executive function are assoc... Read More about The Association of Specific Executive Functions and Falls Risk in People with Mild Cognitive Impairment and Early-Stage Dementia.

Preparatory review of studies of withdrawal of anti-hypertensive medication in older people (2015)
Journal Article
Harrison, J. K., Gladman, J. R., van der Wardt, V., & Conroy, S. (2015). Preparatory review of studies of withdrawal of anti-hypertensive medication in older people. East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series, 3,

Introduction: Since 2012 we have undertaken a programme of research into the management of hypertension in people with dementia. As part of this we are studying the feasibility of withdrawing antihypertensive drugs in people with dementia and well-co... Read More about Preparatory review of studies of withdrawal of anti-hypertensive medication in older people.

General Practitioners’ views of blood pressure control in people with and without dementia (2015)
Journal Article
van der Wardt, V., Conroy, S., Taggar, J., & Gladman, J. R. (2015). General Practitioners’ views of blood pressure control in people with and without dementia. East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series, 1,

Introduction: Since 2012, our group has undertaken a programme of research examining the treatment of hypertension in people with dementia. Hypertension is managed by GPs, who are guided by NICE guidelines, which make no mention of different manageme... Read More about General Practitioners’ views of blood pressure control in people with and without dementia.

P488: The effects of cognitive and exercise interventions for people with mild cognitive impairment and dementia on carers: a systematic review (2014)
Journal Article
Gondek, D., Patel, D. R. K., Pollock, K., das Nair, R., Harwood, R. H., & van der Wardt, V. (in press). P488: The effects of cognitive and exercise interventions for people with mild cognitive impairment and dementia on carers: a systematic review. European Geriatric Medicine, 5(S1), Article S237. https://doi.org/10.1016/S1878-7649%2814%2970653-9

Systematic review into motivational strategies that support adherence to exercise for people with mild cognitive impairment (MCI) or dementia (2014)
Journal Article
Van der Wardt, V., Patel, D. R. K., Gondek, D., Pollock, K., Logan, P., das Nair, R., & Harwood, R. H. (2014). Systematic review into motivational strategies that support adherence to exercise for people with mild cognitive impairment (MCI) or dementia. European Geriatric Medicine, 5(Supp.1), S238. https://doi.org/10.1016/s1878-7649%2814%2970657-6

Introduction: Physical exercise has a positive effect on cognitive functioning, mobility and activities of daily living in people with dementia (Forbes & al., 2013; Pitkälä & al., 2013). Most exercise studies employ motivational strategies to support... Read More about Systematic review into motivational strategies that support adherence to exercise for people with mild cognitive impairment (MCI) or dementia.

A qualitative study into the attitudes of people with mild cognitive impairment and early stages of dementia, and their carers, about falls interventions and risk (2014)
Journal Article
Peach, M., Pollock, K., Harwood, R., Van Der Wardt, V., & Masud, T. (2014). A qualitative study into the attitudes of people with mild cognitive impairment and early stages of dementia, and their carers, about falls interventions and risk. European Geriatric Medicine, 5(S1), S169. doi:10.1016/S1878-7649(14)70440-1

Introduction: Falls are a common and serious problem for older people with cognitive impairment. Successful intervention to reduce falls risk could result in great benefit to patients and their families, and reduce costs. This study examines patients... Read More about A qualitative study into the attitudes of people with mild cognitive impairment and early stages of dementia, and their carers, about falls interventions and risk.

Antihypertensive treatment in people with dementia (2014)
Journal Article
van der Wardt, V., Logan, P. A., Conroy, S., Harwood, R. H., & Gladman, J. R. (2014). Antihypertensive treatment in people with dementia. Journal of the American Medical Directors Association, 15(9), https://doi.org/10.1016/j.jamda.2014.03.005

Introduction The range and magnitude of potential benefits and harms of antihypertensive treatment in people with dementia has not been previously established. Method A scoping review to identify potential domains of benefits and harms of antihyp... Read More about Antihypertensive treatment in people with dementia.