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All Outputs (102)

Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention (2021)
Journal Article
Knight, H., Jia, R., Ayling, K., Bradbury, K., Baker, K., Chalder, T., …Vedhara, K. (2021). Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention. Public Health, 201, 98-107. https://doi.org/10.1016/j.puhe.2021.10.006

Objectives: Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) was identified in late 2019, spreading to over 200 countries and resulting in almost two million deaths worldwide. The emergence of safe and effective vaccines provides a route out of th... Read More about Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention.

Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD) (2021)
Journal Article
Khawagi, W. Y., Steinke, D., Carr, M. J., Wright, A. K., Ashcroft, D. M., Avery, A., & Neil Keers, R. (2022). Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD). BMJ Quality and Safety, 31(5), 364-378. https://doi.org/10.1136/bmjqs-2021-013427

Background: Most patients with mental illness are managed in primary care, yet there is a lack of data exploring potential prescribing safety issues in this setting for this population. Objectives: Examine the prevalence of, between-practice var... Read More about Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD).

Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study (2021)
Journal Article
Pollock, K., Wilson, E., Caswell, G., Latif, A., Caswell, A., Avery, A., …Faul, C. (2021). Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study. Health Services and Delivery Research, 9(14), 1-162. https://doi.org/10.3310/hsdr09140

Background More effective ways of managing symptoms of chronic and terminal illness enable patients to be cared for, and to die, at home. This requires patients and family caregivers to manage complex medicines regimens, including powerful painkille... Read More about Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study.

Strategies supporting sustainable prescribing safety improvement interventions in English primary care: a qualitative study (2021)
Journal Article
Shamsuddin, A., Jeffries, M., Sheikh, A., Laing, L., Salema, N., Avery, A. J., …Keers, R. N. (2021). Strategies supporting sustainable prescribing safety improvement interventions in English primary care: a qualitative study. BJGP Open, 5(5), 1-11. https://doi.org/10.3399/bjgpo.2021.0109

Background: While the use of prescribing safety indicators (PSI) can reduce potentially hazardous prescribing, there is a need to identify actionable strategies for the successful implementation and sustainable delivery of PSI-based interventions in... Read More about Strategies supporting sustainable prescribing safety improvement interventions in English primary care: a qualitative study.

Virtual consultation for red eye (2021)
Journal Article
Ho, C. S., Avery, A. J., Livingstone, I. A., & Ting, D. S. (2021). Virtual consultation for red eye. BMJ, 373, Article n1490. https://doi.org/10.1136/bmj.n1490

This article was written with the aim of helping primary care doctors to reflect on their knowledge and skills in managing common ophthalmic condition such as red eye in the community via virtual consultations. Expert opinions (from both ophthalmolog... Read More about Virtual consultation for red eye.

Anticholinergic drugs and risk of dementia: Time for action? (2021)
Journal Article
Bell, B., Avery, A., Bishara, D., Coupland, C., Ashcroft, D., & Orrell, M. (2021). Anticholinergic drugs and risk of dementia: Time for action?. Pharmacology Research and Perspectives, 9(3), Article e00793. https://doi.org/10.1002/prp2.793

Evidence suggests that the prescription of bladder anticholinergics is increasing. Recent studies have accentuated concerns about whether certain prescribed medications could increase risk of dementia, including anticholinergic drugs, and specificall... Read More about Anticholinergic drugs and risk of dementia: Time for action?.

The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation (2021)
Journal Article
Jeffries, M., Salema, N., Laing, L., Shamsuddin, A., Sheikh, A., Avery, A., …Keers, R. (2021). The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation. PLoS ONE, 16(5), Article e0250946. https://doi.org/10.1371/journal.pone.0250946

Background: The quality and safety of prescribing in general practice is important, Clinical decision support (CDS) systems can be used which present alerts to health professionals when prescribing in order to identify patients at risk of potentiall... Read More about The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation.

From policy to patient: Using a socio-ecological framework to explore the factors influencing safe practice in UK primary care (2021)
Journal Article
Litchfield, I., Perryman, K., Campbell, S., Avery, A., Gill, P., & Greenfield, S. (2021). From policy to patient: Using a socio-ecological framework to explore the factors influencing safe practice in UK primary care. Social Science and Medicine, 277, Article 113906. https://doi.org/10.1016/j.socscimed.2021.113906

Background: The recent and rapid changes in the model of primary care delivery have led to an increased focus on patient safety in what is one of the most diverse and complex healthcare settings. However, previous initiatives have failed to deliver t... Read More about From policy to patient: Using a socio-ecological framework to explore the factors influencing safe practice in UK primary care.

The evaluation of an e-learning prescribing course for general practice (2021)
Journal Article
Salema, N., Clement, N., Hysenagolli, R., Hibberd, R., Bell, B. G., Gookey, G., …Knox, R. (2021). The evaluation of an e-learning prescribing course for general practice. Education for Primary Care, 32(4), 219-225. https://doi.org/10.1080/14739879.2021.1874250

Prescribed medication may lead to significant morbidity or mortality as a result of these medications causing adverse events, or because of a prescribing error. E-learning is a common tool used in supporting training in prescribing. This paper descri... Read More about The evaluation of an e-learning prescribing course for general practice.

Identifying anticholinergic burden in clinical practice (2021)
Journal Article
Bell, B., & Avery, A. (2021). Identifying anticholinergic burden in clinical practice. Prescriber, 32(3), 20-23. https://doi.org/10.1002/psb.1901

Anticholinergic medications are associated with a wide range of adverse effects to which elderly patients are particularly susceptible. This article discusses the various ways that anticholinergic burden can be measured, how these can be used to help... Read More about Identifying anticholinergic burden in clinical practice.

Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis (2020)
Journal Article
Vedhara, K., Royal, S., Sunger, K., Caldwell, D. M., Halliday, V., Taylor, C. M., …Welton, N. J. (2021). Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis. Health Psychology Review, 15(2), 245-271. https://doi.org/10.1080/17437199.2020.1854050

© 2020 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Psychological and behavioural may enhance vaccine effectiveness. We conducted a systematic review and network meta-analysis (NMA) to examine the effects of non-pharmacologi... Read More about Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis.

Incidence, nature and causes of avoidable significant harm in primary care in England: retrospective case note review (2020)
Journal Article
Avery, A. J., Sheehan, C. L., Bell, B. G., Armstrong, S. J., Ashcroft, D. M., Boyd, M. J., …Carson-Stevens, A. (2021). Incidence, nature and causes of avoidable significant harm in primary care in England: retrospective case note review. BMJ Quality and Safety, 30(12), 961-976. https://doi.org/10.1136/bmjqs-2020-011405

Objective To estimate the incidence of avoidable significant harm in primary care in England; describe and classify the associated patient safety incidents and generate suggestions to mitigate risks of ameliorable factors contributing to the incident... Read More about Incidence, nature and causes of avoidable significant harm in primary care in England: retrospective case note review.

Preventable medication harm across health care settings: a systematic review and meta-analysis (2020)
Journal Article
Hodkinson, A., Tyler, N., Ashcroft, D. M., Keers, R. N., Khan, K., Phipps, D., …Campbell, S. (2020). Preventable medication harm across health care settings: a systematic review and meta-analysis. BMC Medicine, 18(1), Article 313. https://doi.org/10.1186/s12916-020-01774-9

Background: Mitigating or reducing the risk of medication harm is a global policy priority. But evidence reflecting preventable medication harm in medical care and the factors that derive this harm remain unknown. Therefore, we aimed to quantify the... Read More about Preventable medication harm across health care settings: a systematic review and meta-analysis.

Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis (2020)
Journal Article
Peek, N., Gude, W. T., Keers, R. N., Williams, R., Kontopantelis, E., Jeffries, M., …Ashcroft, D. M. (2020). Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis. PLoS Medicine, 17(10), Article e1003286. https://doi.org/10.1371/journal.pmed.1003286

Background: We evaluated the impact of the pharmacist-led Safety Medication dASHboard (SMASH) intervention on medication safety in primary care. Methods and findings: SMASH comprised (1) training of clinical pharmacists to deliver the intervention... Read More about Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis.

Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use? (2020)
Journal Article
Mody, S., Kirkdale, C. L., Thornley, T., Dickinson, A., Avery, A. J., Knaggs, R., …Bastable, R. (2020). Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use?. Pharmacy, 8(4), Article 185. https://doi.org/10.3390/pharmacy8040185

The misuse of opioids, including codeine which is sold over-the-counter (OTC) in United Kingdom (UK) community pharmacies, is a growing public health concern. An educational Patient Safety Card was developed and piloted to see if it nudged customers... Read More about Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use?.

Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study (2020)
Journal Article
Jeffries, M., Gude, W. T., Keers, R. N., Phipps, D. L., Williams, R., Kontopantelis, E., …Peek, N. (2020). Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study. BMC Medical Informatics and Decision Making, 20(1), Article 69. https://doi.org/10.1186/s12911-020-1084-5

Background: Improving medication safety is a major concern in primary care settings worldwide. The Salford Medication safety dASHboard (SMASH) intervention provided general practices in Salford (Greater Manchester, UK) with feedback on their safe pre... Read More about Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study.

‘New Medicine Service’: supporting adherence in people starting a new medication for a long-term condition: 26-week follow-up of a pragmatic randomised controlled trial (2019)
Journal Article
Elliott, R. A., Boyd, M., Tanajewski, L., Barber, N., Gkountouras, G., Avery, A. J., …Chuter, A. (2019). ‘New Medicine Service’: supporting adherence in people starting a new medication for a long-term condition: 26-week follow-up of a pragmatic randomised controlled trial. BMJ Quality and Safety, 29(4), 286-295. https://doi.org/10.1136/bmjqs-2018-009177

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Blagojevic-Bucknall, M., Mehta, R., Oppong, R., Avery, A., …Mallen, C. D. (2020). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, 79(2), 276-284. https://doi.org/10.1136/annrheumdis-2019-216154

Objectives: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care. Methods: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general pr... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.