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Obesity in Nigerian Adults and the Associated Cause and Impact on the Population (2022)
Journal Article
Ellecom, J. B., Shaw, I., & Adams, G. G. (2022). Obesity in Nigerian Adults and the Associated Cause and Impact on the Population. Journal of Diabetes Research Reviews & Reports, 4(4), 1-11. https://doi.org/10.47363/JDRR/2022%284%29165

Background: Obesity has been on the rise in developed and developing countries such as Nigeria. Data from the WHO demonstrated the prevalence of obesity increased by 15% between 2002 and 2016 in Nigeria. Here, we examine the rate of obesity in Nigeri... Read More about Obesity in Nigerian Adults and the Associated Cause and Impact on the Population.

Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies (2022)
Journal Article
Alaslani, H., Shaw, I., & Adams, G. (2023). Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies. MOJ Public Health, 11(1), 28-32. https://doi.org/10.15406/mojph.2022.11.00370

Background: Gestational diabetes mellitus (GDM) is a common complication during pregnancy and is associated with adverse pregnancy outcomes and maternal and neonatal risks. Lifestyle intervention through physical activity is generally similar to diet... Read More about Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies.

Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis (2021)
Journal Article
Arabiat, D., Jabery, M. A., Kemp, V., Jenkins, M., Whitehead, L. C., & Adams, G. (2021). Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health, 18(4), Article 1699. https://doi.org/10.3390/ijerph18041699

Studies on the association of maternal diabetes with motor development in children provide inconsistent findings. We searched MEDLINE/PubMed, EMBASE, Emcare, PsycINFO, and Google Scholar databases for primary observational, case–control, or cohort st... Read More about Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis.

Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques (2021)
Journal Article
Gillis, R. B., Solomon, H. V., Govada, L., Oldham, N. J., Dinu, V., Jiwani, S. I., …Adams, G. G. (2021). Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Scientific Reports, 11(1), Article 1737. https://doi.org/10.1038/s41598-021-81251-2

© 2021, The Author(s). This study concerns glulisine, a rapid-acting insulin analogue that plays a fundamental role in diabetes management. We have applied a combination of methods namely X-ray crystallography, and biophysical characterisation to pro... Read More about Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques.

Effectiveness and Safety of Hyperbaric Oxygen Therapy (HBOT) in Treating Diabetic Foot Ulcers (DFUs) (2021)
Journal Article
Alshmimry, A. H., Jiwani, S. I., Gyasi-Antwi, P., & Adams, G. G. (2021). Effectiveness and Safety of Hyperbaric Oxygen Therapy (HBOT) in Treating Diabetic Foot Ulcers (DFUs). Current Research in Clinical Diabetes and Obesity, 01, Article 103. https://doi.org/10.29011/CRCDO-103.100003

Introduction: Diabetic Foot Ulcers (DFUs) are one of the more dangerous complications of diabetes, contributing to morbidity, mortality, and major financial strain, potentially affecting patients' quality of life. Therefore, an effective DFU treatmen... Read More about Effectiveness and Safety of Hyperbaric Oxygen Therapy (HBOT) in Treating Diabetic Foot Ulcers (DFUs).

Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins (2020)
Journal Article
Dinu, V., MacCalman, T., Yang, N., Adams, G. G., Yakubov, G. E., Harding, S. E., & Fisk, I. D. (2020). Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins. European Biophysics Journal, 49(8), 799-808. https://doi.org/10.1007/s00249-020-01475-4

© 2020, The Author(s). Aroma compounds are diverse low molecular weight organic molecules responsible for the flavour of food, medicines or cosmetics. Natural and artificial aroma compounds are manufactured and used by the industry to enhance the fla... Read More about Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins.

Food biotechnology (2020)
Journal Article
Foster, T., Adams, G., di Bari, V., Connerton, I., Gould, J., Gouseti, O., …Yakubov, G. (2020). Food biotechnology. Current Opinion in Chemical Engineering, 30, 53-59. https://doi.org/10.1016/j.coche.2020.08.006

We investigate recent advances in the Chemical Engineering aspects of food structuring agents and macronutrients: carbohydrates, proteins and lipids, and also the fate of food upon ingestion. Prebiotic effects on host-microbe interactions enable impr... Read More about Food biotechnology.

Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis (2020)
Journal Article
Amagyei, A., Meal, A., Shaw, I., & Adams, G. G. (2020). Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis. International Journal of Diabetes, 1(2), 40-50

Objective: Community Health Workers are important in building individual and community capacity through outreach, community education, informal counselling, social support and advocacy programs, which enhance health knowledge and self-sufficiency. Ou... Read More about Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis.

Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review (2020)
Journal Article
Al Oneze, A., Jiwan, S. I., Gyasi-Antw, P., Meal, A., & Adams, G. G. (2020). Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review. Annals of Clinical Diabetes and Endocrinology, 3(2),

Background: The aim of this systematic review is to examine the effectiveness of Liraglutide on glycemic control and Systolic Blood Pressure (SBP) in patients with Type 2 Diabetes (T2D) mellitus and to investigate whether Liraglutide leads to any Gas... Read More about Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review.

Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review (2020)
Journal Article
Naseer, N., Shaw, I., & Adams, G. (2020). Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review. Journal of Diabetes & Metabolic Syndrome, 3(1),

Background: Evidence suggests that all forms of diabetes are on the increase, especially Gestational Diabetes Mellitus (GDM), which increases the risk of maternal and neonatal morbidities. However, the global effect of diet (HA) and lifestyle (PA) of... Read More about Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review.

Global Prevalence of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis (2020)
Journal Article
Gyasi-Antwi, P., Walker, L., Moody, C., Okyere, S., Salt, K., Anang, L., …Adams, G. (2020). Global Prevalence of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis. New American Journal of Medicine, 1(3),

1. Abstract 1.1. Background: Evidence suggests that diabetes in all forms are on the rise especially gesta-tional diabetes mellitus which increases the risk of maternal and neonatal morbidities; however global prevalence rates and geographical distri... Read More about Global Prevalence of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir (2020)
Journal Article
Beji, O., Gillis, R. B., Dinu, V., Jiwani, S. I., Gyasi-Antwi, P., Fisk, I. D., …Adams, G. G. (2020). Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir. European Journal of Pharmaceutics and Biopharmaceutics, 152, 340-347. https://doi.org/10.1016/j.ejpb.2020.05.016

© 2020 Elsevier B.V. Purpose: Insulin, in typical use, undergoes multiple changes in temperature; from refrigerator, to room temperature, to body temperature. Although long-term storage temperature has been well-studied, the short term changes to ins... Read More about Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir.

The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins (2020)
Journal Article
Dinu, V., Lu, Y., Weston, N., Lithgo, R., Coupe, H., Channell, G., …Harding, S. E. (2020). The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins. Scientific Reports, 10(1), Article 960. https://doi.org/10.1038/s41598-020-57776-3

© 2020, The Author(s). Vancomycin, a branched tricyclic glycosylated peptide antibiotic, is a last-line defence against serious infections caused by staphylococci, enterococci and other Gram-positive bacteria. Orally-administered vancomycin is the dr... Read More about The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins.

Management of Diabetes Patients across the Peri- Operative Pathway: A Systematic Review (2020)
Journal Article
Wallace, J., Jiwani, S., Gyasi-Antwi, P., Meal, A., & Adams, G. G. (2020). Management of Diabetes Patients across the Peri- Operative Pathway: A Systematic Review. Endocrinology, Diabetes and Metabolism Journal, 4(1), 1-16

Peri-operative environments are a hazardous setting for diabetes patients. A systematic review of literature regarding the management of diabetes patients across the peri-operative pathway has been undertaken to assess if the management of patients w... Read More about Management of Diabetes Patients across the Peri- Operative Pathway: A Systematic Review.

Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia (2019)
Journal Article
Li, X., Lu, Y., Adams, G. G., Zobel, H., Ballance, S., Wolf, B., & Harding, S. E. (2020). Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia. Food Hydrocolloids, 101, 1-9. https://doi.org/10.1016/j.foodhyd.2019.105446

Scleroglucan, a neutral β(1–3) glucan with β(1–6) glucan branches every third residue, is being considered as an alternative rod-like, shear thinning high molecular weight β-glucan based polysaccharide to xanthan gum for the management of patients wi... Read More about Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia.

Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review (2019)
Journal Article
Thomas, J., Meal, A., & Adams, G. G. (2019). Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review. Journal of Diabetes and Treatment, 4(2), https://doi.org/10.29011/2574-7568.001074

Introduction: This systematic review examines Lipohypertrophy (LH) in patients presenting with Type 1/2 Diabetes (T1/2DM) in relation to education and injection techniques. LH is a condition, which occurs in diabetes individuals at injection sights.... Read More about Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review.

Analysis of Glulisine Crystallisation Utilising Phase Diagrams and Nucleants (2019)
Journal Article
Li, Y., Govada, L., Solomon, H. V., Gillis, R. B., Adams, G. G., & Chayen, N. E. (2019). Analysis of Glulisine Crystallisation Utilising Phase Diagrams and Nucleants. Crystals, 9(9), 1-8. https://doi.org/10.3390/cryst9090462

Glulisine is a US Food and Drug Administration (FDA) approved insulin analogue, used for controlling hyperglycaemia in patients with diabetes mellitus (DM). It is fast acting which better approximates physiological insulin secretion, improving patien... Read More about Analysis of Glulisine Crystallisation Utilising Phase Diagrams and Nucleants.

Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour (2019)
Journal Article
Dinu, V., Yakubov, G. E., Lim, M., Hurst, K., Adams, G. G., Harding, S. E., & Fisk, I. D. (2019). Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour. International Journal of Biological Macromolecules, 138, 831-836. https://doi.org/10.1016/j.ijbiomac.2019.07.148

To reduce animal testing, there is a need to develop novel in-vitro models for evaluating the retention of bioactive compounds in food and pharmaceutical products. Here, a mucus-mimetic platform was developed through a one-step approach based on enca... Read More about Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour.

An enzymatically controlled mucoadhesive for enhancing flavour during food oral processing (2019)
Journal Article
Dinu, V., Gadon, A., Hurst, K., Lim, M., Ayed, C., Gillis, R. B., …Fisk, I. D. (2019). An enzymatically controlled mucoadhesive for enhancing flavour during food oral processing. npj Science of Food, 3(1), Article 11. https://doi.org/10.1038/s41538-019-0043-y

While a good mucoadhesive biopolymer must adhere to a mucus membrane, it must also have a good unloading ability. Here, we demonstrate that the biopolymer pullulan is partially digested by human salivary α-amylase, thus acting as a controlled release... Read More about An enzymatically controlled mucoadhesive for enhancing flavour during food oral processing.

Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity (2019)
Journal Article
Dinu, V., Gillis, R. B., MacCalman, T., Lim, M., Adams, G. G., Harding, S. E., & Fisk, I. D. (2019). Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity. Food Biophysics, 14(3), 278-286. https://doi.org/10.1007/s11483-019-09574-2

Submaxillary mucin is a major component that defines the makeup and functionality of saliva. Understanding its structure and function during food intake is key to designing appropriate strategies for enhancing the delivery of flavour. In the present... Read More about Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity.