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Educational weight loss interventions in obese and overweight adults with Type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials (2019)
Journal Article
Maula, A., Kai, J., Woolley, A. K., Weng, S., Dhalwani, N., Griffiths, F., …Kendrick, D. (2019). Educational weight loss interventions in obese and overweight adults with Type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials. Diabetic Medicine, https://doi.org/10.1111/dme.14193

Introduction: The worldwide prevalence of type 2 diabetes mellitus (T2DM) is increasing with most individuals being overweight or obese. Weight loss can reduce disease-related morbidity and mortality, and weight losses of 10-15Kg have been shown to... Read More about Educational weight loss interventions in obese and overweight adults with Type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials.

Metronidazole versus lactic acid for treating bacterial vaginosis (VITA): protocol for a randomised controlled trial to assess the clinical and cost effectiveness of topical lactic acid gel for treating second and subsequent episodes of bacterial vaginosi (2019)
Journal Article
Armstrong-Buisseret, L., Brittain, C., David, M., Dean, G., Griffiths, F., Hepburn, T., …Ross, J. D. (2019). Metronidazole versus lactic acid for treating bacterial vaginosis (VITA): protocol for a randomised controlled trial to assess the clinical and cost effectiveness of topical lactic acid gel for treating second and subsequent episodes of bacterial vaginosis. Trials, 20, https://doi.org/10.1186/s13063-019-3731-7

Background: Bacterial vaginosis (BV) affects 30 – 50% of women at some time in their lives and is an embarrassing and distressing condition which can be associated with potentially serious comorbidities. Current antibiotic treatments such as metronid... Read More about Metronidazole versus lactic acid for treating bacterial vaginosis (VITA): protocol for a randomised controlled trial to assess the clinical and cost effectiveness of topical lactic acid gel for treating second and subsequent episodes of bacterial vaginosi.

The ‘New Medicine Service’: supporting adherence in people starting a new medication for a long-term condition: 26-week follow up of a pragmatic randomised controlled trial (2019)
Journal Article
Elliott, R. A., Boyd, M., Tanajewski, L., Barber, N., Gkountouras, G., Avery, A. J., …Chuter, A. (2019). The ‘New Medicine Service’: supporting adherence in people starting a new medication for a long-term condition: 26-week follow up of a pragmatic randomised controlled trial. BMJ Quality and Safety, https://doi.org/10.1136/bmjqs-2018-009177+

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Blagojevic-Bucknall, M., Mehta, R., Oppong, R., Avery, A., …Mallen, C. D. (2019). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, https://doi.org/10.1136/annrheumdis-2019-216154

Objectives: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care. Methods: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general pr... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

The drugs don't work: evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance (2019)
Journal Article
Ahmed, R., Bashir, A., Brown, J. E., Cox, J. A., Hilton, A. C., Hilton, C. E., …Worthington, T. (2019). The drugs don't work: evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2019.10.011

Summary: Increased public awareness of antimicrobial resistance (AMR) is a key component of effective antimicrobial stewardship strategies. Educational theatre combined with an expert panel was used to engage the public about AMR through delivery of... Read More about The drugs don't work: evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance.

GP views on their role in bullying disclosure by children and young people in the community: a cross-sectional qualitative study in English primary care (2019)
Journal Article
Prasad, V., & Condon, L. (2019). GP views on their role in bullying disclosure by children and young people in the community: a cross-sectional qualitative study in English primary care. British Journal of General Practice, 69(688), e752-e759. https://doi.org/10.3399/bjgp19X706013

Background: Bullying among children and young people (CYP) is a major public health concern which can lead to physical and mental health consequences. CYP may disclose bullying, and seek help from, their general practitioner (GP). However, there is c... Read More about GP views on their role in bullying disclosure by children and young people in the community: a cross-sectional qualitative study in English primary care.

A comparison of six osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia (2019)
Journal Article
Shean Toh, L., Lai, P. S. M., Wu, D. B., Bell, B. G., Dang, C. P. L., Low, B. Y., …Anderson, C. (2019). A comparison of six osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia. Osteoporosis and Sarcopenia, https://doi.org/10.1016/j.afos.2019.09.001

Objectives To compare and assess the performance of 6 osteoporosis risk assessment tools for screening osteoporosis in Malaysian postmenopausal women. Methods Six osteoporosis risk assessments tools (the Simple Calculated Osteoporosis Risk Estim... Read More about A comparison of six osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia.

Re-Configuring Identity Postpartum and Sustained Abstinence or Relapse to Tobacco Smoking (2019)
Journal Article
Brown, T. J., Bauld, L., Hardeman, W., Holland, R., Naughton, F., Orton, S., …Notley, C. (2019). Re-Configuring Identity Postpartum and Sustained Abstinence or Relapse to Tobacco Smoking. International Journal of Environmental Research and Public Health, 16(17), 1-11. doi:10.3390/ijerph16173139

Relapse to smoking postpartum is a common and important public health problem. Difficulty in adjusting to a non-smoking identity is a key factor prompting relapse. However, postpartum relapse prevention interventions rarely focus upon offering suppor... Read More about Re-Configuring Identity Postpartum and Sustained Abstinence or Relapse to Tobacco Smoking.

Interest in and use of smoking cessation support across pregnancy and postpartum (2019)
Journal Article
Naughton, F., Reeves Vaz, L., Coleman, T., Orton, S., Bowker, K., Leonardi-Bee, J., …Ussher, M. (2019). Interest in and use of smoking cessation support across pregnancy and postpartum. Nicotine and Tobacco Research, https://doi.org/10.1093/ntr/ntz151

Background: Limited research exists on interest in and use of smoking cessation support in pregnancy and postpartum. Methods: A longitudinal cohort of pregnant smokers and recent ex-smokers were recruited in Nottinghamshire, UK (N=850). Data were... Read More about Interest in and use of smoking cessation support across pregnancy and postpartum.

Users’ experiences of a pragmatic diabetes prevention intervention implemented in primary care: Qualitative study (2019)
Journal Article
Aujla, N., Yates, T., Dallosso, H., & Kai, J. (2019). Users’ experiences of a pragmatic diabetes prevention intervention implemented in primary care: Qualitative study. BMJ Open, 9, doi:10.1136/bmjopen-2018-028491

Objectives: To explore service-user and provider experience of the acceptability and feasibility of the Let’s Prevent Diabetes programme, a pragmatic six-hour behavioural intervention using structured group education, introduced into primary care pra... Read More about Users’ experiences of a pragmatic diabetes prevention intervention implemented in primary care: Qualitative study.

Pregnant Smokers’ Experiences and Opinions of Techniques Aimed to Address Barriers and Facilitators to Smoking Cessation: A Qualitative Study (2019)
Journal Article
Fergie, L., Coleman, T., Ussher, M., Cooper, S., & Campbell, K. A. (2019). Pregnant Smokers’ Experiences and Opinions of Techniques Aimed to Address Barriers and Facilitators to Smoking Cessation: A Qualitative Study. International Journal of Environmental Research and Public Health, 16(15), doi:10.3390/ijerph16152772

Pregnant women experience certain barriers and facilitators (B&Fs) when trying to quit smoking. This study aimed to elicit women’s views on techniques that could help overcome or enhance these. Semi-structured interviews were conducted with 12 pregna... Read More about Pregnant Smokers’ Experiences and Opinions of Techniques Aimed to Address Barriers and Facilitators to Smoking Cessation: A Qualitative Study.

A systematic review of personal smart technologies used to improve outcomes in adults with acquired brain injuries (2019)
Journal Article
Kettlewell, J., das Nair, R., & Radford, K. (2019). A systematic review of personal smart technologies used to improve outcomes in adults with acquired brain injuries. Clinical Rehabilitation, doi:10.1177/0269215519865774

Objective: This review aimed to determine the effectiveness of personal smart technologies on outcomes in adults with acquired brain injury. Data sources: A systematic literature search was conducted on 30 May 2019. Twelve electronic databases,... Read More about A systematic review of personal smart technologies used to improve outcomes in adults with acquired brain injuries.

The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort (2019)
Journal Article
Nowakowska, M., Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., …Kontopantelis, E. (2019). The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. BMC Medicine, 17(1), doi:10.1186/s12916-019-1373-y

Background: The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of comorbidities in this population. The aims of this study are to quanti... Read More about The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort.

Protocol to assess risk of breast cancer associated with use of hormone replacement therapy in real world settings: two nested case-control studies in primary care. (2019)
Other
Vinogradova, Y., Coupland, C., & Hippisley-Cox, J. Protocol to assess risk of breast cancer associated with use of hormone replacement therapy in real world settings: two nested case-control studies in primary care

Hormone replacement therapy (HRT) is used to help women suffering from menopausal symptoms and reduce risk of osteoporosis. Although effective, the therapy may lead to an increased risk of breast cancer. Previous studies have not been powerful enou... Read More about Protocol to assess risk of breast cancer associated with use of hormone replacement therapy in real world settings: two nested case-control studies in primary care..

Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary care and secondary care datasets (2019)
Journal Article
Jack, R. H., Hollis, C., Coupland, C., Morriss, R., Knaggs, R. D., Cipriani, A., …Hippisley-Cox, J. (2019). Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary care and secondary care datasets. Evidence-Based Mental Health, 22(3), 129-133. doi:10.1136/ebmental-2019-300097

Introduction Increasing numbers of children and young people (CYP) are receiving prescriptions for antidepressants. This is the protocol of a study aiming to describe the trends and variation in antidepressant prescriptions in CYP in England, and t... Read More about Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary care and secondary care datasets.

Factors influencing adherence to home-based strength and balance exercises among older adults with mild cognitive impairment and early dementia: Promoting Activity, Independence and Stability in Early Dementia (PrAISED) (2019)
Journal Article
Hancox, J. E., Van Der Wardt, V., Pollock, K., Booth, V., Vedhara, K., & Harwood, R. H. (2019). Factors influencing adherence to home-based strength and balance exercises among older adults with mild cognitive impairment and early dementia: Promoting Activity, Independence and Stability in Early Dementia (PrAISED). PLoS ONE, 14(5), doi:10.1371/journal.pone.0217387

Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis (2019)
Journal Article
Whitemore, R., Leonardi-Bee, J., Naughton, F., Sutton, S., Cooper, S., Parrott, S., …Coleman, T. (2019). Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis. Trials, 20, 1-13. doi:10.1186/s13063-019-3341-4

Background: Smoking in pregnancy is a major international public health problem. Self-help support (SHS) increases the likelihood of women stopping smoking in pregnancy and delivering this kind of support by text message could be a cost-effective way... Read More about Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis.