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Service dogs (2019)
Book Chapter
Harvey, N. (2019). Service dogs. In J. Vonk, & T. K. Shackelford (Eds.), Encyclopedia of Animal Cognition and Behavior

Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models (2019)
Journal Article
Mukhamedshina, Y., Shulman, I., Ogurcov, S., Kostennikov, A., Zakirova, E., Akhmetzyanova, E., …Rizvanov, A. (2019). Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models. Biomolecules, 9(12), https://doi.org/10.3390/biom9120811

Here, we provide a first comparative study of the therapeutic potential of allogeneic mesenchymal stem cells derived from bone marrow (BM-MSCs), adipose tissue (AD-MSCs), and dental pulp (DP-MSCs) embedded in fibrin matrix, in small (rat) and large (... Read More about Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models.

Quantitative analysis of calf mortality in Great Britain (2019)
Journal Article
Hyde, R. M., Green, M. J., Sherwin, V. E., Hudson, C., Gibbons, J., Forshaw, T., …Down, P. M. (in press). Quantitative analysis of calf mortality in Great Britain. Journal of Dairy Science,

National bodies in Great Britain (GB) have expressed concern over young stock health and welfare and identified calf survival as a priority, however no national data have been available to quantify mortality rates. The aim of this study was to quanti... Read More about Quantitative analysis of calf mortality in Great Britain.

Field survey to evaluate space allowances for diary cows in Great Britain (2019)
Journal Article
Thompson, J., Huxley, J., Hudson, C., Kaler, J., Gibbons, J., & Green, M. (in press). Field survey to evaluate space allowances for diary cows in Great Britain. Journal of Dairy Science,

Housing conditions can affect health by increasing exposure to biological, chemical and physical hazards, resulting in increased disease. A report in 2014 indicated that 99% of UK dairy cows are housed during winter months and that an increasing numb... Read More about Field survey to evaluate space allowances for diary cows in Great Britain.

Therapeutic Application of Mesenchymal Stem Cells Derived Extracellular Vesicles for Immunomodulation (2019)
Journal Article
Gomzikova, M. O., James, V., & Rizvanov, A. A. (2019). Therapeutic Application of Mesenchymal Stem Cells Derived Extracellular Vesicles for Immunomodulation. Frontiers in Immunology, 10, https://doi.org/10.3389/fimmu.2019.02663

The immunosuppressive potential of mesenchymal stem cells has been extensively investigated in many studies in vivo and in vitro. In recent years, a variety preclinical and clinical studies have demonstrated that mesenchymal stem cells ameliorate imm... Read More about Therapeutic Application of Mesenchymal Stem Cells Derived Extracellular Vesicles for Immunomodulation.

Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk (2019)
Journal Article
Es-Haghi, M., Godakumara, K., Häling, A., Lättekivi, F., Lavrits, A., Viil, J., …Fazeli, A. (2019). Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk. Cell Communication and Signaling, 17(1), https://doi.org/10.1186/s12964-019-0448-x

Induction and measurement of the early stage of a host‐parasite interaction using a combined optical trapping and Raman micro‐spectroscopy system (2019)
Journal Article
Sinjab, F., Elsheikha, H. M., Dooley, M., & Notingher, I. (2019). Induction and measurement of the early stage of a host‐parasite interaction using a combined optical trapping and Raman micro‐spectroscopy system. Journal of Biophotonics, https://doi.org/10.1002/jbio.201960065

Understanding and quantifying the temporal acquisition of host cell molecules by intracellular pathogens is fundamentally important in biology. In this study, a recently developed holographic optical trapping (HOT)-based Raman micro-spectroscopy (RMS... Read More about Induction and measurement of the early stage of a host‐parasite interaction using a combined optical trapping and Raman micro‐spectroscopy system.

Production and Application of Multicistronic Constructs for Various Human Disease Therapies (2019)
Journal Article
Shaimardanova, A. A., Kitaeva, K. V., Abdrakhmanova, I. I., Chernov, V. M., Rutland, C. S., Rizvanov, A. A., …Solovyeva, V. V. (2019). Production and Application of Multicistronic Constructs for Various Human Disease Therapies. Pharmaceutics, 11, 580. https://doi.org/10.3390/pharmaceutics11110580

The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes. To date, the exampl... Read More about Production and Application of Multicistronic Constructs for Various Human Disease Therapies.

Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures (2019)
Journal Article
Wang, Z., Hu, R., Zhou, C., He, J., M. Elsheikha, H., & Zhu, X. (2019). Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures. Microorganisms, 7(11), 1-19. https://doi.org/10.3390/microorganisms7110510

Distinct genotypic and pathogenic differences exist between Toxoplasma gondii genotypes. For example, genotype I is highly virulent, whereas genotype II and genotype III are less virulent. Moreover, Chinese 1 genotype (ToxoDB#9) is also virulent. Her... Read More about Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures.

Animals, veterinarians and the sociology of diagnosis (2019)
Journal Article
Hobson‐West, P., & Jutel, A. (2019). Animals, veterinarians and the sociology of diagnosis. Sociology of Health and Illness, https://doi.org/10.1111/1467-9566.13017

While sociologists of medicine have focused their efforts on understanding human health, illness, and medicine, veterinary medical practice has not yet caught their attention in any sustained way. In this critical review paper, we use insights from t... Read More about Animals, veterinarians and the sociology of diagnosis.

Potential therapeutic application of mesenchymal stem cells in ophthalmology (2019)
Journal Article
Zakirova, E. Y., Valeeva, A., Aimaletdinov, A., Nefedovskaya, L., Akhmetshin, R., Rutland, C., & Rizvanov, A. (2019). Potential therapeutic application of mesenchymal stem cells in ophthalmology. Experimental Eye Research, https://doi.org/10.1016/j.exer.2019.107863

At present a wide variety of methods have been proposed to treat eye disorders, drug therapies are most commonly used. It should be noted that effective treatment modalities especially for degeneration of the retina and optic nerve are lacking. In th... Read More about Potential therapeutic application of mesenchymal stem cells in ophthalmology.

Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells (2019)
Journal Article
Brearley, M. C., Li, C., Daniel, Z. C., Loughna, P. T., Parr, T., & Brameld, J. M. (2019). Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells. Biochemistry and Biophysics Reports, 20, https://doi.org/10.1016/j.bbrep.2019.100694

Skeletal muscle is a highly metabolic and dynamic tissue that is formed through the complex and well-organised process of myogenesis. Although there is a good understanding about the role of the Muscle Regulatory Factors during myogenesis, little is... Read More about Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells.

Antigen array for serological diagnosis and novel allergen identification in severe equine asthma (2019)
Journal Article
White, S. J., Moore-Colyer, M., Marti, E., Hannant, D., Gerber, V., Coüetil, L., …Alcocer, M. (2019). Antigen array for serological diagnosis and novel allergen identification in severe equine asthma. Scientific Reports, 9, https://doi.org/10.1038/s41598-019-51820-7

Severe equine asthma (sEA), which closely resembles human asthma, is a debilitating and performance-limiting allergic respiratory disorder which affects 14% of horses in the Northern Hemisphere and is associated with increased allergen-specific immun... Read More about Antigen array for serological diagnosis and novel allergen identification in severe equine asthma.

Extracellular vesicles in the diagnosis and treatment of central nervous system diseases (2019)
Journal Article
Shaimardanova, A. A., Solovyeva, V. V., Chulpanova, D. S., James, V., Kitaeva, K. V., & Rizvanov, A. A. (2020). Extracellular vesicles in the diagnosis and treatment of central nervous system diseases. Neural Regeneration Research, 15(4), 586=596. https://doi.org/10.4103/1673-5374.266908

Extracellular vesicles, exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system (CNS) with all body system... Read More about Extracellular vesicles in the diagnosis and treatment of central nervous system diseases.

Behavioural Differences in Dogs with Atopic Dermatitis Suggest Stress Could Be a Significant Problem Associated with Chronic Pruritus (2019)
Journal Article
Harvey, N. D., Craigon, P. J., Shaw, S. C., Blott, S. C., & England, G. C. (2019). Behavioural Differences in Dogs with Atopic Dermatitis Suggest Stress Could Be a Significant Problem Associated with Chronic Pruritus. Animals, 9(10), https://doi.org/10.3390/ani9100813

Canine atopic dermatitis (cAD) is a common allergic skin condition in dogs that causes chronic pruritus. The overall quality of life in dogs with cAD is known to be reduced, and human patients with pruritic conditions report significant psychological... Read More about Behavioural Differences in Dogs with Atopic Dermatitis Suggest Stress Could Be a Significant Problem Associated with Chronic Pruritus.

Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection (2019)
Journal Article
Kydd, J. H., Hannant, D., Robinson, R. S., Bryant, N., & Osterrieder, N. (2019). Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection. Vaccine, https://doi.org/10.1016/j.vaccine.2019.09.106

Equid herpesvirus-1 (EHV-1) causes respiratory and neurological disease and late gestation abortion in pregnant mares. Current vaccines contain either inactivated or live EHV-1, but fail to provide complete clinical or virological protection, namely... Read More about Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection.

Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection (2019)
Journal Article
Kydd, J. H., & Hannant, D. (2019). Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection. Vaccine, https://doi.org/10.1016/j.vaccine.2019.09.106

Equid herpesvirus-1 (EHV-1) causes respiratory and neurological disease and late gestation abortion in pregnant mares. Current vaccines contain either inactivated or live EHV-1, but fail to provide complete clinical or virological protection, namely... Read More about Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection.

Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts (2019)
Journal Article
Zhang, X., Cwiklinski, K., Hu, R., Zheng, W., Sheng, Z., Zhang, F., …Zhu, X. (2019). Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts. BMC Genomics, 20, 1-18. https://doi.org/10.1186/s12864-019-6103-5

Background The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important disease of humans and livestock. We characterized dynamic transcriptional changes associated with the development of the parasite in its two hosts, the snail in... Read More about Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts.

A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms (2019)
Journal Article
Kumssa, D. B., Penrose, B., Bone, P. A., Lovatt, A., Broadley, M. R., Kendall, N. R., & Ander, L. (2019). A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms. PLoS ONE, 14(10), https://doi.org/10.1371/journal.pone.0223868

Hypomagnesaemic tetany (HypoMgT) in ruminants is a physiological disorder caused by inadequate intake or impaired absorption of magnesium (Mg) in the gut. If it is not detected and treated in time, HypoMgT can cause the death of the affected animal.... Read More about A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms.