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The neurobiological basis of sex differences in learned fear and its inhibition (2019)
Journal Article
Day, H. L., & Stevenson, C. W. (2019). The neurobiological basis of sex differences in learned fear and its inhibition. European Journal of Neuroscience, https://doi.org/10.1111/ejn.14602

Learning that certain cues or environments predict threat enhances survival by promoting appropriate fear and the resulting defensive responses. Adapting to changing stimulus contingencies by learning that such cues no longer predict threat, or disti... Read More about The neurobiological basis of sex differences in learned fear and its inhibition.

Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle (2019)
Journal Article
Garnsworthy, P. C., Difford, G. F., Bell, M. J., Bayat, A. R., Huhtanen, P., Kuhla, B., …Yan, T. (2019). Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle. Animals, 9(10), https://doi.org/10.3390/ani9100837

Partners in Expert Working Group WG2 of the COST Action METHAGENE (www.methagene.eu) have used several methods for measuring methane output by individual dairy cattle under various environmental conditions. Methods included respiration chambers, the... Read More about Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle.

Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream (2019)
Journal Article
Vargas-Bello-Pérez, E., Cancino-Padilla, N., Geldsetzer-Mendoza, C., Vyhmeister, S., Morales, M. S., Leskinen, H., …Ibáñez, R. A. (2019). Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream. Animals, 9(8), 1-13. https://doi.org/10.3390/ani9080568

Simple Summary: The objective of this study was to evaluate the effects of supplementation of dairy cows' diets with different fatty acid (FA) sources on milk production, milk composition, milk fatty acid profile, and physicochemical and sensory char... Read More about Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream.

A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos (2019)
Journal Article
Canizo, J. R., Ynsaurralde Rivolta, A. E., Vazquez Echegaray, C., Suvá, M., Alberio, V., Aller, J. F., …Alberio, R. (2019). A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos. BMC Developmental Biology, 19(1), 1-13. https://doi.org/10.1186/s12861-019-0193-9

Background The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence s... Read More about A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos.

A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions (2019)
Journal Article
Wallace, R. J., Sasson, G., Garnsworthy, P. C., Tapio, I., Gregson, E., Bani, P., …Mizrahi, I. (2019). A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions. Science Advances, 5(7), doi:10.1126/sciadv.aav8391

A 1000-cow study across four European countries was undertaken to understand to what extent ruminant microbiomes can be controlled by the host animal and to identify characteristics of the host rumen microbiome axis that determine productivity and me... Read More about A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions.

Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows (2019)
Journal Article
Breider, I., Wall, E., & Garnsworthy, P. (2019). Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows. Journal of Dairy Science, 102(8), 7277-7281. doi:10.3168/jds.2018-15909

Greenhouse gases originating from the dairy sector, including methane (CH 4), contribute to global warming. A possible strategy to reduce CH 4 production is to use genetic selection. This requires genetic parameters for CH 4 production and correlatio... Read More about Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows.

The overlooked cohort? – Improving the taught postgraduate student experience in higher education (2019)
Journal Article
Coneyworth, L., Jessop, R., Maden, P., & White, G. (2019). The overlooked cohort? – Improving the taught postgraduate student experience in higher education. Innovations in Education and Teaching International, 1-12. doi:10.1080/14703297.2019.1617184

Taught postgraduate students in the UK have a limited timeframe for study, with most full-time courses requiring intense scholarship, typically over a 12-month period. Many of these students face challenges and concerns with the transition from under... Read More about The overlooked cohort? – Improving the taught postgraduate student experience in higher education.

Cannabinoid regulation of fear and anxiety: an update (2019)
Journal Article
Papagianni, E. P., & Stevenson, C. W. (2019). Cannabinoid regulation of fear and anxiety: an update. Current Psychiatry Reports, 21(6), 1-10. doi:10.1007/s11920-019-1026-z

Purpose of Review Anxiety- and trauma-related disorders are prevalent and debilitating mental illnesses associated with a significant socioeconomic burden. Current treatment approaches often have inadequate therapeutic responses, leading to symptom... Read More about Cannabinoid regulation of fear and anxiety: an update.

Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs (2019)
Journal Article
Harris, J. R., Goff, M., Jenkins, H., Harris, J., Knowles, T. B., Lascelles, B. D., …Murrell, J. C. (2019). Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs. Veterinary Anaesthesia and Analgesia, 46(4), 483-487. doi:10.1016/j.vaa.2018.11.010

Objective: To describe clinically relevant, physiological measurements collected during a 3- hour duration alfaxalone total intravenous anaesthesia. Study design: Case series. Animals: A total of 112 client-owned middle aged or older dogs. Methods... Read More about Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs.

Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs (2019)
Journal Article
Curry, S. M., Blavi, L., Wiseman, J., & Stein, H. H. (2019). Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs. Translational Animal Science, 3(2), doi:10.1093/tas/txz005

Two experiments were conducted to compare the standardized ileal digestibility (SID) of AA by growing pigs in European distillers dried grains with solubles (DDGS) produced from wheat, maize, or wheat–maize mixtures and to test the effect of increasi... Read More about Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs.

Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning (2019)
Journal Article
Stubbendorff, C., Hale, E., Cassaday, H. J., Bast, T., & Stevenson, C. W. (2019). Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning. Psychopharmacology, doi:10.1007/s00213-018-5162-7

Rationale Dopamine D1 receptor (D1R) signalling is involved in contextual fear conditioning. The D1R antagonist SCH23390 impairs the acquisition of contextual fear when administered systemically or infused locally into the dorsal hippocampus or ba... Read More about Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning.

Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves (2018)
Journal Article
Handyside, A. H., Turner, K. J., Silvestri, G., Black, D. H., Dobson, G., Smith, C., …Griffin, D. K. (2019). Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves. Theriogenology, 125, 249-258. https://doi.org/10.1016...riogenology.2018.11.014

© 2018 The Authors In cattle breeding, the development of genomic selection strategies based on single nucleotide polymorphism (SNP) interrogation has led to improved rates of genetic gain. Additionally, the application of genomic selection to in-vit... Read More about Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves.

One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development (2018)
Journal Article
Clare, C. E., Brassington, A. H., Kwong, W. Y., & Sinclair, K. D. (2019). One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development. Annual Review of Animal Biosciences, 7(1), doi:10.1146/annurev-animal-020518-115206

One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that include the methionine and folate cycles that are central to cellular function, providing 1C units (methyl groups) for the synthesis of DNA, polyamines, amino acids... Read More about One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development.

The effect of supplementary ultraviolet wavelengths on broiler chicken welfare indicators (2018)
Journal Article
James, C., Asher, L., Herborn, K., & Wiseman, J. (2018). The effect of supplementary ultraviolet wavelengths on broiler chicken welfare indicators. Applied Animal Behaviour Science, 209, 55-64. doi:10.1016/j.applanim.2018.10.002

Qualities of the light environment are important for good welfare in a number of species. In chickens, UVA light is visible and may facilitate flock interactions. UVB wavelengths promote endogenous vitamin D synthesis, which could support the rapid s... Read More about The effect of supplementary ultraviolet wavelengths on broiler chicken welfare indicators.

Effect of different exogenous fatty acids on the cytosolic triacylglycerol content in bovine mammary cells (2018)
Journal Article
Vargas-Bello-Pérez, E., Loor, J. J., & Garnsworthy, P. C. (2018). Effect of different exogenous fatty acids on the cytosolic triacylglycerol content in bovine mammary cells. Animal Nutrition, doi:10.1016/j.aninu.2018.09.002

The objective of this study was to determine how cytosolic triacylglycerols (TAG) are stored in mammary cells and whether this depends on the individual chemical configuration of fatty acids (FA). This objective was accomplished by addition of differ... Read More about Effect of different exogenous fatty acids on the cytosolic triacylglycerol content in bovine mammary cells.

Testicular function and bone in young men with severe childhood-onset obesity. (2018)
Journal Article
Anand-Ivell, R., Ivell, R., Laakso, S., Viljakainen, H., Lipsanen-Nyman, M., Turpeinen, U., …Mäkitie, O. (2018). Testicular function and bone in young men with severe childhood-onset obesity. Hormone Research in Paediatrics, 89(6), (442–449). doi:10.1159/000489818. ISSN 1663-2818

Background: Previous studies suggest increased risk for hypoandrogenism and fractures in men with obesity. We aimed to describe the effects of severe childhood-onset obesity on the cross talk between metabolic state, testes and skeleton at late puber... Read More about Testicular function and bone in young men with severe childhood-onset obesity..

Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis (2018)
Journal Article
Murrell, J. C., Whay, H. R., Mendl, M., Lascelles, B. D. X., Hunt, J. R., Hunt, J. R., …Murrell, J. C. (2018). Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis. PAIN, 159(11), 2318-2330. https://doi.org/10.1097/j.pain.0000000000001336

In man, central sensitisation (CS) contributes to the pain of osteoarthritis (OA). Dogs with spontaneous OA may also exhibit CS. Electrophysiological reflex measurements are more objective than behavioural assessments, and can be used to evaluate CS... Read More about Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis.

Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum (2018)
Journal Article
Anand-Ivell, R., Juul, A., & Albrethsen, J. (2018). Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum. Clinical Chemistry and Laboratory Medicine, 56(11), doi:10.1515/cclm-2018-0171

BACKGROUND: The circulating level of the peptide hormone insulin-like factor 3 (INSL3) is a promising diagnostic marker reflecting Leydig cell function in the male. Few commercial immunoassays of varying quality exist. Therefore, we decided to devel... Read More about Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum.

Short communication: Development of an equation for estimating methane emissions of dairy cows from milk Fourier transform mid-infrared spectra by using reference data obtained exclusively from respiration chambers (2018)
Journal Article
Vanlierde, A., Soyeurt, H., Gengler, N., Colinet, F., Froidmont, E., Kreuzer, M., …Dehareng, F. (2018). Short communication: Development of an equation for estimating methane emissions of dairy cows from milk Fourier transform mid-infrared spectra by using reference data obtained exclusively from respiration chambers. Journal of Dairy Science, 101(8), 7618-7624. https://doi.org/10.3168/jds.2018-14472

Evaluation and mitigation of enteric methane (CH4) emissions from ruminant livestock, in particular from dairy cows, have acquired global importance for sustainable, climate-smart cattle production. Based on CH4 reference measurements obtained with t... Read More about Short communication: Development of an equation for estimating methane emissions of dairy cows from milk Fourier transform mid-infrared spectra by using reference data obtained exclusively from respiration chambers.