All Outputs (45313)

Responsible AI in policing (2024)
Presentation / Conference Contribution
Webb, H., Fitzroy-Dale, N., Aqeel, S., Piskopani, A.-M., Stafford-Fraser, Q., Dowthwaite, L., McAuley, D., & Hargreaves, C. (2024, September). Responsible AI in policing. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS '24), Austin, Texas, USA

The deployment of AI-driven technologies in policing is often welcomed as an opportunity to enhance efficiency in dealing with crime. At the same time, however, these technologies pose risks around data bias, data protection, accuracy and privacy. In... Read More about Responsible AI in policing.

Perceived negativity in British general election communications (2024)
Journal Article
Milazzo, C., & Ryan, J. B. (2024). Perceived negativity in British general election communications. Electoral Studies, 92, Article 102863. https://doi.org/10.1016/j.electstud.2024.102863

British parties – and their candidates – frequently engage in the use of negative messaging. While previous studies shed light on the frequency and source of such messages, we know less about how negative messages are received. In this research note,... Read More about Perceived negativity in British general election communications.

Graphical Abstract Enhanced Offshore Wind Resource Assessment Using Hybrid Data Fusion and Numerical Models (2024)
Journal Article
Elshafei, B., Popov, A., & Giddings, D. (in press). Graphical Abstract Enhanced Offshore Wind Resource Assessment Using Hybrid Data Fusion and Numerical Models. Energy,

Wind resource assessments are crucial for pre-construction planning of wind farms, especially offshore. This study proposes a novel hybrid model integrating Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) and Empirical Wa... Read More about Graphical Abstract Enhanced Offshore Wind Resource Assessment Using Hybrid Data Fusion and Numerical Models.

Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice (2024)
Journal Article
Morgan, H. L., Eid, N., Holmes, N., Henson, S., Wright, V., Coveney, C., Winder, C., O’Neil, D. M., Dunn, W. B., Boocock, D. J., & Watkins, A. J. (2024). Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice. BMC Biology, 22, Article 207. https://doi.org/10.1186/s12915-024-01992-0

Background: The importance of parental diet in relation to eventual offspring health is increasing in prominence due to the increased frequency of parents of reproductive age consuming poor diets. Whilst maternal health and offspring outcome have bee... Read More about Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice.

Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial (2024)
Journal Article
Sheehan, L., Woodward, A., Adamson, J., Archer, M., Drummond, A., Hewison, A., Jordan, C., Keding, A., Kottam, L., Madan, I., Martland, M., McDaid, C., McDonald, D. A., Parkinson, G., Reed, M., Sinclair, L., Smith, T. O., Thomson, L., Watkins, L., Wu, Q., & Baker, P. (2024). Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial. BMJ Open, 14(9), Article e085962. https://doi.org/10.1136/bmjopen-2024-085962

Background: In the UK, one in four patients are in work at the time of their hip or knee replacement surgery. These patients receive little support about their return to work (RTW). There is a need for an occupational support intervention that encour... Read More about Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial.

The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19 (2024)
Journal Article
Vilar-Lluch, S., McClaughlin, E., Adolphs, S., Knight, D., & Nichele, E. (2024). The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19. Text and Talk - An Interdisciplinary Journal of Language, Discourse and Communication Studies, https://doi.org/10.1515/text-2023-0125

Health messaging is effective if it is to achieve audience adherence to guidance. Through the lens of Systemic Functional Linguistics, we examine the expression of obligation in poster-based health campaigns (4 posters) employed during the COVID-19 p... Read More about The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19.

Examining the Feasibility of AI-Generated Questions in Educational Settings (2024)
Presentation / Conference Contribution
Zeghouani, O., Ali, Z., Simson Van Dijkhuizen, W., Wei Hong, J., & Clos, J. (2024, September). Examining the Feasibility of AI-Generated Questions in Educational Settings. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS '24), Austin, Texas, USA

Educators face ever-growing time constraints, leading to poor work-life balance and a negative impact on work quality. Through their language generation capabilities, large language models offer an interesting avenue to ease this academic workload, a... Read More about Examining the Feasibility of AI-Generated Questions in Educational Settings.

A Multimethod Analysis of US Perspectives towards Trustworthy Autonomous Systems (2024)
Presentation / Conference Contribution
Barnard, P., Boudouraki, A., & Clos, J. (2024, September). A Multimethod Analysis of US Perspectives towards Trustworthy Autonomous Systems. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS '24), Austin, Texas

The Trustworthy Autonomous Systems (TAS) Hub is a collabora-tive platform that aims to guide the development of autonomous systems that are safe, reliable, and ultimately trusted by society. Its mission is to address the challenges surrounding the gr... Read More about A Multimethod Analysis of US Perspectives towards Trustworthy Autonomous Systems.

Investigating the Impact of Generative AI on Students and Educators: Evidence and Insights from the Literature (2024)
Presentation / Conference Contribution
Clos, J., & Chen, Y. Y. (2024, September). Investigating the Impact of Generative AI on Students and Educators: Evidence and Insights from the Literature. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS ’24), Austin, Texas

Generative artificial intelligence (AI) has become one of the main concerns of knowledge workers due to its ability to mimic realistic human reasoning and creativity. However, this integration raises critical concerns about trust and ethics, which ar... Read More about Investigating the Impact of Generative AI on Students and Educators: Evidence and Insights from the Literature.

LOOM: a Privacy-Preserving Linguistic Observatory of Online Misinformation (2024)
Presentation / Conference Contribution
Clos, J., McClaughlin, E., Barnard, P., Tom, T., & Yajaman, S. (2024, September). LOOM: a Privacy-Preserving Linguistic Observatory of Online Misinformation. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS ’24), Austin, Texas, USA

Online misinformation is an ever-growing challenge that can have a negative impact on individuals, societies, and democracies. We report on LOOM, a project that aims to build and validate a browser-based tool to detect and respond to misinformation i... Read More about LOOM: a Privacy-Preserving Linguistic Observatory of Online Misinformation.

Responsibility and Regulation: Exploring Social Measures of Trust in Medical AI (2024)
Presentation / Conference Contribution
McGarry, G., Crabtree, A., Chamberlain, A., & Urquhart, L. D. (2024, September). Responsibility and Regulation: Exploring Social Measures of Trust in Medical AI. Presented at Second International Symposium on Trustworthy Autonomous Systems (TAS ’24), Austin, Texas, USA

This paper explores expert accounts of autonomous systems (AS) development in the medical device domain (MD) involving applications of artificial intelligence (AI), machine learning (ML), and other algorithmic and mathematical modelling techniques. W... Read More about Responsibility and Regulation: Exploring Social Measures of Trust in Medical AI.

Perception and neurocognitive aging (2024)
Book Chapter
Allen, H. (2024). Perception and neurocognitive aging. In Encyclopedia of the Human Brain. (2). Elsevier

There are sensory changes and decline in all senses, although people are often more aware of the changes in vision and hearing than those in touch, smell and taste. In the first part of this article, I will summarize and discuss these changes. In the... Read More about Perception and neurocognitive aging.

A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter (2024)
Journal Article
Ding, Q., Cai, J., Jin, L., Hu, W., Song, W., Rose, P., Tang, Z., Zhan, Y., Bao, L., Lei, W., & Zhu, Y. Z. (2024). A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter. MedComm, 5(10), Article e711. https://doi.org/10.1002/mco2.711

SMYD3 (SET and MYND domain-containing 3) is a histone lysine methyltransferase highly expressed in different types of cancer(s) and is a promising epigenetic target for developing novel antitumor therapeutics. No selective inhibitors for this protein... Read More about A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter.

Structuring white rice with gellan gum reduces the glycemic response in healthy humans (2024)
Journal Article
Alshammari, N. A., Riches, K., Muttakin, S., Hoad, C. L., Strkalj, L., Gouseti, O., Bakalis, S., Lovegrove, A., Spiller, R. C., Gowland, P. A., Aithal, G. P., Yakubov, G. E., Taylor, M. A., & Marciani, L. (2024). Structuring white rice with gellan gum reduces the glycemic response in healthy humans. Food Research International, 196, Article 115090. https://doi.org/10.1016/j.foodres.2024.115090

White rice has a high glycemic index and its consumption has been linked to an increased risk of developing type-2 diabetes mellitus, increased diabetes associated complications and obesity. In recent in vitro studies we have shown that addition of f... Read More about Structuring white rice with gellan gum reduces the glycemic response in healthy humans.

Comparative judgement modeling to map forced marriage at local levels (2024)
Journal Article
Seymour, R., Nyarko-Agyei, A., Mccabe, H., Severn, K., Sirl, D., Kypraios, T., & Taylor, A. (in press). Comparative judgement modeling to map forced marriage at local levels. Annals of Applied Statistics,

Forcing someone into marriage against their will is a violation of their human rights. In 2021, the county of Nottinghamshire, UK, launched a strategy to tackle forced marriage and violence against women and girls. We set out to map the risk of force... Read More about Comparative judgement modeling to map forced marriage at local levels.

Short-term risk of cardiovascular events in people newly diagnosed with gout (2024)
Journal Article
Cipolletta, E., Nakafero, G., Richette, P., Avery, A. J., Mamas, M. A., Tata, L. J., & Abhishek, A. (2024). Short-term risk of cardiovascular events in people newly diagnosed with gout. Arthritis and Rheumatology, https://doi.org/10.1002/art.42986

Objectives
To investigate the temporal association between first diagnosis of gout and cardiovascular events in the short-term.

Methods
We performed a self-controlled case series analysis and a cohort study using data from linked primary care, h... Read More about Short-term risk of cardiovascular events in people newly diagnosed with gout.

Microplastics pollution in sediments of the Thames and Medway estuaries, UK: Organic matter associations and predominance of polyethylene (2024)
Journal Article
Trusler, M. M., Moss-Hayes, V. L., Cook, S., Lomax, B. H., & Vane, C. H. (2024). Microplastics pollution in sediments of the Thames and Medway estuaries, UK: Organic matter associations and predominance of polyethylene. Marine Pollution Bulletin, 208, Article 116971. https://doi.org/10.1016/j.marpolbul.2024.116971

Microplastics at 10 sites along a 77 km transect of the river Thames estuary (UK) and 5 sites along 29 km of the Medway estuary were separated from sediment and analysed by ATR-FTIR spectroscopy. Microplastics were observed at all sites. Highest Tham... Read More about Microplastics pollution in sediments of the Thames and Medway estuaries, UK: Organic matter associations and predominance of polyethylene.

High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy (2024)
Journal Article
Makarovsky, O., Hill, R. J. A., Cheng, T. S., Summerfield, A., Taniguchi, T., Watanabe, K., Mellor, C. J., Patanè, A., Eaves, L., Novikov, S. V., & Beton, P. H. (2024). High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy. Communications Materials, 5, Article 189. https://doi.org/10.1038/s43246-024-00633-x

High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy Graphene placed on hexagonal boron nitride (hBN) has received significant interest due to its excellent electrical performan... Read More about High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy.

The Structure of Massive Star-Forming Galaxies from JWST and ALMA: Dusty, High Redshift Disk Galaxies (2024)
Journal Article
Gillman, S., Smail, I., Gullberg, B., Swinbank, A., Vijayan, A. P., Lee, M., Brammer, G., Dudzeviciute, U., Greve, T. R., Almaini, O., Brinch, M., Chapman, S. C., Chen, C.-C., Ikarashi, S., Matsuda, Y., Wang, W.-H., Walter, F., & van der Werf, P. P. (in press). The Structure of Massive Star-Forming Galaxies from JWST and ALMA: Dusty, High Redshift Disk Galaxies. Astronomy and Astrophysics,

We present an analysis of the JWST NIRCam and MIRI morphological and structural properties of 80 massive (log10(M∗[M]) = 11.2 ± 0.1) dusty star-forming galaxies at z = 2.7+1.2 −0.7 , identified as sub-millimetre galaxies (SMGs) by ALMA, that have bee... Read More about The Structure of Massive Star-Forming Galaxies from JWST and ALMA: Dusty, High Redshift Disk Galaxies.

The Discovery of Substituted 5-(2-Hydroxybenzoyl)-2-Pyridone Analogues as Inhibitors of the Human Caf1/CNOT7 Ribonuclease (2024)
Journal Article
Kaur, I., Jadhav, G. P., Fischer, P. M., & Winkler, G. S. (2024). The Discovery of Substituted 5-(2-Hydroxybenzoyl)-2-Pyridone Analogues as Inhibitors of the Human Caf1/CNOT7 Ribonuclease. Molecules, 29(18), Article 4351. https://doi.org/10.3390/molecules29184351

The Caf1/CNOT7 nuclease is a catalytic component of the Ccr4-Not deadenylase complex, which is a key regulator of post-transcriptional gene regulation. In addition to providing catalytic activity, Caf1/CNOT7 and its paralogue Caf1/CNOT8 also contribu... Read More about The Discovery of Substituted 5-(2-Hydroxybenzoyl)-2-Pyridone Analogues as Inhibitors of the Human Caf1/CNOT7 Ribonuclease.