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All Outputs (76)

Association between serum urate, gout and comorbidities: a case–control study using data from the UK Biobank (2020)
Journal Article
Sandoval-Plata, G., Nakafero, G., Chakravorty, M., Morgan, K., & Abhishek, A. (2021). Association between serum urate, gout and comorbidities: a case–control study using data from the UK Biobank. Rheumatology, 60(7), 3243-3251. https://doi.org/10.1093/rheumatology/keaa773

Objectives To examine the association between comorbidities and serum urate (SU), gout and comorbidities, and to determine whether the association between gout and comorbidities is independent of SU. Methods We performed a case-control study using UK... Read More about Association between serum urate, gout and comorbidities: a case–control study using data from the UK Biobank.

Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown? (2020)
Journal Article
Shur, N., Johns, . D., Kluzek, S., & Peirce, N. (2020). Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown?. BMJ Open Sport and Exercise Medicine, 6(1), Article e000903. https://doi.org/10.1136/bmjsem-2020-000903

Government-restricted movement during the coronavirus pandemic in various countries around the world has led to rapid and fundamental changes in our health behaviour. As well as being at a higher risk of contracting and being hospitalised with COVID-... Read More about Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown?.

BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK (2020)
Journal Article
Pearce, F. A., Rutter, M., Sandhu, R., Batten, R. L., Garner, R., Little, J., …Lanyon, P. C. (2021). BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK. Rheumatology, 60(3), 1480-1490. https://doi.org/10.1093/rheumatology/keaa759

Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal fo... Read More about BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK.

Scoping the international impact from four independent national dermatology trials (2020)
Journal Article
Williams, H. C., Rogers, N. K., Chalmers, J. R., & Thomas, K. S. (2021). Scoping the international impact from four independent national dermatology trials. Clinical and Experimental Dermatology, 46(4), 657-662. https://doi.org/10.1111/ced.14506

Background: Research impact describes whether and how research results in wider benefits to society beyond academic publication. Little is known about translation of clinical trial research into dermatological practice. Aim: We scoped international i... Read More about Scoping the international impact from four independent national dermatology trials.

Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic (2020)
Journal Article
Peach, E., Rutter, M., Lanyon, P., Grainge, M. J., Hubbard, R., Aston, J., …Pearce, F. (2021). Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic. Rheumatology, 60(4), 1902–1909. https://doi.org/10.1093/rheumatology/keaa855

Objectives: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. Methods: We conducted a cohort s... Read More about Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic.

A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults (2020)
Journal Article
Taha, R. H. M., Grindlay, D., Deshmukh, S., Montgomery, A., Davis, T. R. C., & Karanatana, A. (2022). A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults. Hand, 17(5), 869-878. https://doi.org/10.1177/1558944720974363

Metacarpal shaft fractures are common hand injuries that predominantly affect younger patients. There is wide variability in their treatment with no consensus on best practice. We performed a systematic review to assess the breadth and quality of ava... Read More about A Systematic Review of Treatment Interventions for Metacarpal Shaft Fractures in Adults.

Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT (2020)
Journal Article
Batchelor, J. M., Thomas, K. S., Akram, P., Azad, J., Bewley, A., Chalmers, J. R., …Montgomery, A. A. (2020). Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT. Health Technology Assessment, 24(64), 1-164. https://doi.org/10.3310/hta24640

Background: Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo. Objective: To explore the clinical effectiveness and cost-effecti... Read More about Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT.

Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs (2020)
Journal Article
Abdulrahim, H., Jiao, Q., Swain, S., Sehat, K., Sarmanova, A., Muir, K., …Doherty, M. (2021). Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs. Annals of the Rheumatic Diseases, 80(4), 494-501. https://doi.org/10.1136/annrheumdis-2020-218739

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: To evaluate the risk of association with hip osteoarthritis (OA) of 14 morphological features measured on standard antero-posteri... Read More about Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs.

A self-report questionnaire to detect hand dermatitis in nurses (2020)
Journal Article
Parsons, V., Williams, H. C., English, J., Llewellyn, J., Ntani, G., & Madan, I. (2020). A self-report questionnaire to detect hand dermatitis in nurses. Occupational Medicine, 70(9), 645-648. https://doi.org/10.1093/occmed/kqaa188

Background: Hand dermatitis is highly prevalent among nurses due to their frequent exposure to wet work. Providing cost-effective dermatological health surveillance for this occupational group presents a challenge to health service providers. Aims: T... Read More about A self-report questionnaire to detect hand dermatitis in nurses.

Interventions for basal cell carcinoma of the skin (2020)
Journal Article
Thomson, J., Hogan, S., Leonardi-Bee, J., Williams, H. C., & Bath-Hextall, F. J. (2020). Interventions for basal cell carcinoma of the skin. Cochrane Library, 2020, Article CD003412. https://doi.org/10.1002/14651858.CD003412.pub3

Background: Basal cell carcinoma (BCC) is the commonest cancer affecting white-skinned individuals, and worldwide incidence is increasing. Although rarely fatal, BCC is associated with significant morbidity and costs. First-line treatment is usually... Read More about Interventions for basal cell carcinoma of the skin.

Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials (2020)
Journal Article
Persson, M. S., Stocks, J., Sarmanova, A., Fernandes, G., Walsh, D. A., Doherty, M., & Zhang, W. (2021). Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials. Rheumatology, 60(5), 2231-2237. https://doi.org/10.1093/rheumatology/keaa561

OBJECTIVES: To determine individual responses to ibuprofen gel or capsaicin cream for painful, radiographic knee OA using a series of n-of-1 trials. METHODS: Twenty-two participants were allocated 5% ibuprofen gel (A) and 0.025% capsaicin cream (B) i... Read More about Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials.

Optimising recruitment to the HAND-1 RCT feasibility study: integration of the QuinteT Recruitment Intervention (QRI) (2020)
Journal Article
Husbands, S., Elliott, D., Davis, T. R., Blazeby, J. M., Harrison, E. F., Montgomery, A. A., …Mills, N. (2020). Optimising recruitment to the HAND-1 RCT feasibility study: integration of the QuinteT Recruitment Intervention (QRI). Pilot and Feasibility Studies, 6(1), https://doi.org/10.1186/s40814-020-00710-1

© 2020, The Author(s). Background: Recruitment to randomised controlled trials (RCTs) can be challenging, with most trials not reaching recruitment targets. Randomised feasibility studies can be set up prior to a main trial to identify and overcome r... Read More about Optimising recruitment to the HAND-1 RCT feasibility study: integration of the QuinteT Recruitment Intervention (QRI).

Fostering global data sharing: Highlighting the recommendations of the Research Data Alliance COVID-19 working group (2020)
Journal Article
Austin, C. C., Bernier, A., Bezuidenhout, L., Bicarregui, J., Biro, T., Cambon-Thomsen, A., …Uhlmansiek, M. (2020). Fostering global data sharing: Highlighting the recommendations of the Research Data Alliance COVID-19 working group. Wellcome Open Research, 5, Article 267. https://doi.org/10.12688/wellcomeopenres.16378.1

© 2020 Austin CC et al. The systemic challenges of the COVID-19 pandemic require cross-disciplinary collaboration in a global and timely fashion. Such collaboration needs open research practices and the sharing of research outputs, such as data and c... Read More about Fostering global data sharing: Highlighting the recommendations of the Research Data Alliance COVID-19 working group.

An economic evaluation of the randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo (the HI-Light Vitiligo Trial)* (2020)
Journal Article
Sach, T., Thomas, K., Batchelor, J., Akram, P., Chalmers, J., Haines, R., …The UK Dermatology Clinical Trials Network’s HI‐LIGHT Vitiligo Trial Team. (2021). An economic evaluation of the randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo (the HI-Light Vitiligo Trial)*. British Journal of Dermatology, 184(5), 840-848. https://doi.org/10.1111/bjd.19554

Background: Economic evidence for vitiligo treatments is absent. Objectives: To determine the cost-effectiveness of (i) handheld narrowband ultraviolet B (NB-UVB) and (ii) a combination of topical corticosteroid (TCS) and NB-UVB compared with TCS alo... Read More about An economic evaluation of the randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo (the HI-Light Vitiligo Trial)*.

Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT (2020)
Journal Article
Dias, J., Brealey, S., Cook, L., Fairhurst, C., Hinde, S., Leighton, P., …Torgerson, D. (2020). Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT. Health Technology Assessment, 24(52), a-234. https://doi.org/10.3310/hta24520

Background: Scaphoid fractures account for 90% of carpal fractures and occur predominantly in young men. Immediate surgical fixation of this fracture has increased. Objective: To compare the clinical effectiveness and cost-effectiveness of surgical f... Read More about Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT.

Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis (2020)
Journal Article
Perry, T., Yang, X., van Santen, J., Arden, N., & Kluzek, S. (2021). Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis. Journal of Rheumatology, 60(4), 1763-1773. https://doi.org/10.1093/rheumatology/keaa619

Objectives: Synovitis in symptomatic knee osteoarthritis (KOA) is common and is associated with joint symptoms. Optimal synovial measurement on magnetic resonance imaging (MRI) is however, unclear. Our aims were to examine the relationship between MR... Read More about Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis.

Estimation of the burden of shielding among a cross-section of patients attending rheumatology clinics with SLE-data from the BSR audit of systemic lupus erythematosus (2020)
Journal Article
Rutter, M., Lanyon, P. C., Sandhu, R., Batten, R. L., Garner, R., Little, J., …Pearce, F. A. (2021). Estimation of the burden of shielding among a cross-section of patients attending rheumatology clinics with SLE-data from the BSR audit of systemic lupus erythematosus. Rheumatology, 60(3), 1474-1479. https://doi.org/10.1093/rheumatology/keaa620

Objectives: We aimed to estimate what proportion of people with SLE attending UK rheumatology clinics would be categorized as being at high risk from coronavirus disease 2019 (COVID-19) and therefore asked to shield, and explore what implications thi... Read More about Estimation of the burden of shielding among a cross-section of patients attending rheumatology clinics with SLE-data from the BSR audit of systemic lupus erythematosus.

An interview study of the experiences of cellulitis diagnosis amongst health care professionals (2020)
Journal Article
Patel, M., Ing Lee, S., Levell, N. J., Smart, P., Kai, J., Thomas, K. S., & Leighton, P. (2020). An interview study of the experiences of cellulitis diagnosis amongst health care professionals. BMJ Open, 10(10), Article e034692. https://doi.org/10.1136/+bmjopen-2019-034692

Objectives: To explore healthcare professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis. Setting: UK nationwide. Participants: 20 qualified HCPs, who had a minimum of 2 years clinical experience as an HCP... Read More about An interview study of the experiences of cellulitis diagnosis amongst health care professionals.

An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK (2020)
Journal Article
Patel, M., Lee, S., Levell, N., Smart, P., Kai, J., Thomas, K., & Leighton, P. (2020). An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK. BMJ Open, 10, Article e034692. https://doi.org/10.1136/bmjopen-2019-034692

Objectives: To explore health care professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis. Setting: UK nationwide. Participants: 20 qualified HCPs, who had a minimum of two years clinical experience as a... Read More about An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK.